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8441por Cui, Huan-Xian, Liu, Ran-Ran, Zhao, Gui-Ping, Zheng, Mai-Qing, Chen, Ji-Lan, Wen, Jie“…These findings establish the groundwork and provide new clues for deciphering the molecular mechanisms underlying IMF deposition in poultry. …”
Publicado 2012
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8442por Nyamweya, Samuel, Townend, John, Zaman, Akram, Steele, Sarah Jane, Jeffries, David, Rowland-Jones, Sarah, Whittle, Hilton, Flanagan, Katie L., Jaye, Assan“…Assessment of soluble biomarkers indicating immune activation provide clues into pathogenesis and hold promise for the development of point-of-care monitoring of HIV in resource-poor-settings. …”
Publicado 2012
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8443por López, Elena, Cuadrado, Carmen, Burbano, Carmen, Jiménez, Maria Aranzazu, Rodríguez, Julia, Crespo, Jesús F“…Glycosylation studies provided us with clues to elucidate, in the near future, mechanisms of the structures that contribute to hazelnut allergenicity, which thus, in turn, help alleviate food allergens.…”
Publicado 2012
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8444por Liu, Lin-Na, Xu, Hui-Xiong, Lu, Ming-De, Xie, Xiao-Yan, Wang, Wen-Ping, Hu, Bing, Yan, Kun, Ding, Hong, Tang, Shao-Shan, Qian, Lin-Xue, Luo, Bao-Ming, Wen, Yan-Ling“…A multiple logistic regression analysis was performed to identify diagnostic clues from 17 independent variables that enabled differentiation between malignant and benign GB diseases. …”
Publicado 2012
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8445“…The results of this meta-analysis of human lung cancer microRNA expression profiling studies might provide some clues of the potential biomarkers in lung cancer. …”
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8446“…Such a model is expected to substantially improve the QSAR ability from single cell lines, and provide useful clues in developing clinically effective inhibitors and modifications of parent lead compounds for target on the Hedgehog Signaling Pathway. …”
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8447“…CONCLUSIONS: Our study presented an efficient, extendable and quantitative computational model for integration of different compound representations, and expected to provide new clues to improve the virtual drug screening from various pharmacological properties. …”
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8448por Annadurai, Ramasamy S, Jayakumar, Vasanthan, Mugasimangalam, Raja C, Katta, Mohan AVSK, Anand, Sanchita, Gopinathan, Sreeja, Sarma, Santosh Prasad, Fernandes, Sunjay Jude, Mullapudi, Nandita, Murugesan, S, Rao, Sudha Narayana“…CONCLUSION: Solid molecular signatures (transcripts related to bixin, abscisic acid, and geranial and geraniol biosynthesis) for the anti-diabetic properties of C. pictus leaves and vital clues related to the other phytochemical functions like antitumor, anti-oxidant, immuno-modulatory, anti-microbial and anti-malarial properties through the secondary metabolite pathway annotations are reported. …”
Publicado 2012
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8449por Takahashi, Hiro, Iwakawa, Hidekazu, Ishibashi, Nanako, Kojima, Shoko, Matsumura, Yoko, Prananingrum, Pratiwi, Iwasaki, Mayumi, Takahashi, Anna, Ikezaki, Masaya, Luo, Lilan, Kobayashi, Takeshi, Machida, Yasunori, Machida, Chiyoko“…Previously, we developed the knowledge-based fuzzy adaptive resonance theory (KB-FuzzyART), a clustering algorithm suitable for analyzing gene expression data, to find clues for identifying gene networks. Leaf primordia form around the shoot apical meristem (SAM), which consists of indeterminate stem cells. …”
Publicado 2013
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8450por Jensen, Kirsty, Günther, Juliane, Talbot, Richard, Petzl, Wolfram, Zerbe, Holm, Schuberth, Hans-Joachim, Seyfert, Hans-Martin, Glass, Elizabeth J“…Understanding the underlying mechanisms may provide further clues for ways to control mammary gland infections. …”
Publicado 2013
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8451por Algra, Selma O, Groeneveld, Kathelijne M, Schadenberg, Alvin WL, Haas, Felix, Evens, Fabiola CM, Meerding, Jenny, Koenderman, Leo, Jansen, Nicolaas JG, Prakken, Berent J“…This phenomenon may hold important clues for the understanding of the inflammatory response to stroke and its potentially detrimental consequences. …”
Publicado 2013
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8452por O'Brien, Katie M., Orlow, Irene, Antonescu, Cristina R., Ballman, Karla, McCall, Linda, DeMatteo, Ronald, Engel, Lawrence S.“…This preliminary analysis of inherited genetic risk factors for GIST offers some clues about the disease's genetic origins and provides a starting point for future candidate gene or gene-environment research.…”
Publicado 2013
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8453por Foglia Manzillo, Valentina, Di Muccio, Trentina, Cappiello, Sivia, Scalone, Aldo, Paparcone, Rosa, Fiorentino, Eleonora, Gizzarelli, Manuela, Gramiccia, Marina, Gradoni, Luigi, Oliva, Gaetano“…Altogether our findings indicate that any susceptible young dogs naturally infected by L. infantum present a common pattern of progression of signs during 2 years post infection, providing clues for medical and epidemiological applied aspects.…”
Publicado 2013
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8454por Robbins, David E., Grüneberg, Alexander, Deus, Helena F., Tanik, Murat M., Almeida, Jonas S.“…The development of the TCGA Roadmap engine was found to provide specific clues about how biomedical big data initiatives should be exposed as public resources for exploratory analysis, data mining and reproducible research. …”
Publicado 2013
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8455por Saad, Rama, Chen, Zheng, Zhu, Shoumin, Jia, Peilin, Zhao, Zhongming, Washington, M. Kay, Belkhiri, Abbes, El-Rifai, Wael“…This may provide some clues for the distinct molecular features of EAC to be considered in future studies of the role of miRNAs in EAC and their utility as disease biomarkers.…”
Publicado 2013
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8456“…Its study may give important clues to understand the evolution of rhodopemorphs among basal heterobranchs versus their previously thought origin among ‘higher’ euthyneuran taxa. …”
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8457“…This comparative analysis has yielded clues as to how rearrangements occur, and the identification of sets of genes that appear to be associated with these events.…”
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8458por Kawata, Kazuhito, Tsuda, Masanobu, Yang, Guo-Xiang, Zhang, Weici, Tanaka, Hajime, Tsuneyama, Koichi, Leung, Patrick, He, Xiao-Song, Knechtle, Stuart, Ansari, Aftab A., Coppel, Ross L., Gershwin, M. Eric“…In particular, we have constructed several unique gene-deleted mice, including mice deleted of IL-12p40, IL-12p35, IFN-γ, IL-23p19, IL-17A, IL-17F and IL-22, immunized these animals with 2OA-BSA and followed the natural history of immunopathology to identify key pathways that might provide clues for successful therapy. Our data indicate that whereas both IL-12/Th1 and IL-23/Th17 are involved in cholangitis, it is the IL-12/Th1 signaling pathway that elicits pathology. …”
Publicado 2013
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8459por Degenkolbe, Elisa, König, Jana, Zimmer, Julia, Walther, Maria, Reißner, Carsten, Nickel, Joachim, Plöger, Frank, Raspopovic, Jelena, Sharpe, James, Dathe, Katarina, Hecht, Jacqueline T., Mundlos, Stefan, Doelken, Sandra C., Seemann, Petra“…These novel insights into the biology of GDF5 might also provide further clues on the pathophysiology of OA.…”
Publicado 2013
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8460por Gruszczyk, Jakub, Olivares-Illana, Vanesa, Nourikyan, Julien, Fleurie, Aurore, Béchet, Emmanuelle, Gueguen-Chaignon, Virginie, Freton, Céline, Aumont-Nicaise, Magali, Moréra, Solange, Grangeasse, Christophe, Nessler, Sylvie“…This structural analysis did not provide the expected clues about the activation discrepancy observed between the two modulators. …”
Publicado 2013
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