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8461por Gabaldón, Toni, Martin, Tiphaine, Marcet-Houben, Marina, Durrens, Pascal, Bolotin-Fukuhara, Monique, Lespinet, Olivier, Arnaise, Sylvie, Boisnard, Stéphanie, Aguileta, Gabriela, Atanasova, Ralitsa, Bouchier, Christiane, Couloux, Arnaud, Creno, Sophie, Almeida Cruz, Jose, Devillers, Hugo, Enache-Angoulvant, Adela, Guitard, Juliette, Jaouen, Laure, Ma, Laurence, Marck, Christian, Neuvéglise, Cécile, Pelletier, Eric, Pinard, Amélie, Poulain, Julie, Recoquillay, Julien, Westhof, Eric, Wincker, Patrick, Dujon, Bernard, Hennequin, Christophe, Fairhead, Cécile“…We uncover duplications and accelerated evolution that specifically affected genes in the lineage preceding the group containing N. delphensis and the three pathogens, which may provide clues to the higher propensity of this group to infect humans. …”
Publicado 2013
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8462por Janssen, Sarah F, Gorgels, Theo GMF, van der Spek, Peter J, Jansonius, Nomdo M, Bergen, Arthur AB“…This study aims to elucidate the molecular machinery of the most important function of the CBE: the AH production and composition, and aims to find possible new molecular clues for POAG and AH production-lowering drugs. …”
Publicado 2013
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8463por Zhang, Ning-Ning, Liu, Yu-Tao, Ma, Li, Wang, Lin, Hao, Xue-Zhi, Yuan, Zheng, Lin, Dong-Mei, Li, Dan, Zhou, Yu-Jie, Lin, Hua, Han, Xiao-Hong, Sun, Yan, Shi, Yuankai“…IHC could provide more clues for clinical trial design and therapeutic strategies for ALK-positive NSCLC patients including patients with double genetic aberration of ALK and EGFR.…”
Publicado 2014
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8464por Pu, Yuanyuan, Gao, Jie, Guo, Yanli, Liu, Tingting, Zhu, Lixia, Xu, Ping, Yi, Bin, Wen, Jing, Tu, Jinxing, Ma, Chaozhi, Fu, Tingdong, Zou, Jitao, Shen, Jinxiong“…These findings offer novel clues for elucidating the molecular basis of the glossy phenotype.…”
Publicado 2013
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8465por Giordano, Carla, Iommarini, Luisa, Giordano, Luca, Maresca, Alessandra, Pisano, Annalinda, Valentino, Maria Lucia, Caporali, Leonardo, Liguori, Rocco, Deceglie, Stefania, Roberti, Marina, Fanelli, Francesca, Fracasso, Flavio, Ross-Cisneros, Fred N., D’Adamo, Pio, Hudson, Gavin, Pyle, Angela, Yu-Wai-Man, Patrick, Chinnery, Patrick F., Zeviani, Massimo, Salomao, Solange R., Berezovsky, Adriana, Belfort, Rubens, Ventura, Dora Fix, Moraes, Milton, Moraes Filho, Milton, Barboni, Piero, Sadun, Federico, De Negri, Annamaria, Sadun, Alfredo A., Tancredi, Andrea, Mancini, Massimiliano, d’Amati, Giulia, Loguercio Polosa, Paola, Cantatore, Palmiro, Carelli, Valerio“…Our study provides a valuable mechanism to explain variability of penetrance in Leber’s hereditary optic neuropathy and clues for high throughput genetic screening to identify the nuclear modifying gene(s), opening an avenue to develop predictive genetic tests on disease risk and therapeutic strategies.…”
Publicado 2014
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8466por Park, Jun Young, Choi, Moon Seok, Lim, Young-Suk, Park, Jang Won, Kim, Seung Up, Min, Yang Won, Gwak, Geum-Youn, Paik, Yong-Han, Lee, Joon Hyoek, Koh, Kwang Cheol, Paik, Seung Woon, Yoo, Byung Chul“…CONCLUSIONS: CT and MRI provide clues to the diagnosis of IPT in patients with liver masses and normal tumor markers. …”
Publicado 2014
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8467“…CONCLUSIONS: Our findings provide an overview of potential miRNAs involved in pollen development and interactions between miRNAs and their corresponding targets, which may provide important clues on the function of miRNAs in pollen development.…”
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8468por Mashiyama, Susan T., Malabanan, M. Merced, Akiva, Eyal, Bhosle, Rahul, Branch, Megan C., Hillerich, Brandan, Jagessar, Kevin, Kim, Jungwook, Patskovsky, Yury, Seidel, Ronald D., Stead, Mark, Toro, Rafael, Vetting, Matthew W., Almo, Steven C., Armstrong, Richard N., Babbitt, Patricia C.“…A deeper understanding of relationships across the superfamily could provide new clues about their functions. To establish a foundation for expanded classification of cytGSTs, we generated similarity-based subgroupings for the entire superfamily. …”
Publicado 2014
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8469por Ren, Xiao-Xin, Ma, Li, Liu, Qing-Wei, Li, Chuan, Huang, Zhong, Wu, Li, Xiong, Si-Dong, Wang, Jian-Hua, Wang, Hai-Bo“…The novel finding of DC-mediated EV71 dissemination might facilitate elucidation of EV71 primary infection and benefit searching for new clues for preventing viruses from initial infection.…”
Publicado 2014
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8470por Gannavaram, Sreenivas, Dey, Ranadhir, Avishek, Kumar, Selvapandiyan, Angamuthu, Salotra, Poonam, Nakhasi, Hira L.“…In addition, comparative analysis of biomarkers in PBMCs from asymptomatic or healed visceral leishmaniasis individuals in response to vaccine candidates including live attenuated parasites may provide clues about determinants of protective immunity and be helpful in shaping the final Leishmania vaccine formulation in the clinical trials.…”
Publicado 2014
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8471por Kooy, Marcel J, van Geffen, Erica CG, Heerdink, Eibert R, van Dijk, Liset, Bouvy, Marcel L“…By measuring satisfaction with information and counselling and beliefs about medication the study will also give clues for the reason of a potential increase in adherence. …”
Publicado 2014
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8472por Bu, Yuanyuan, Zhao, Mengqing, Sun, Bo, Zhang, Xinxin, Takano, Tetsuo, Liu, Shenkui“…Although analysis of expression patterns in model organisms like yeast and Arabidopsis can provide important clues about protein localization, these heterologous systems may not always faithfully reflect the native subcellular distribution in other species. …”
Publicado 2014
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8473por Turlier, Virginie, Viode, Cécile, Durbise, Elisabeth, Bacquey, Adeline, LeJeune, Ophélie, Oliveira Soares, Rui, Lauze, Christophe, Villeneuve, Cécile, Rouquier, Amandine, Casas, Christiane, Redoules, Daniel, Mengeaud, Valérie, Schmitt, Anne-Marie“…Correlations between clinical signs and biomarkers could provide clues to explain the resolution of SD and confirm the interest of biomarkers for SD treatment assessment. …”
Publicado 2014
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8474por Clark, Robert D, Liang, Wenkel, Lee, Adam C, Lawless, Michael S, Fraczkiewicz, Robert, Waldman, Marvin“…Finally, the profiles for models whose predictive uncertainty estimates are not reliable provide clues to that effect without the need for comparison to an external test set.…”
Publicado 2014
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8475“…Therefore, we analyzed CYP19P1 and CYP19A1 transcripts with the aim to detect clues for gene–pseudogene interference. FINDINGS: The CYP19P1 transcript was first examined in silico for the presence of microRNA coding sequences and microRNA targets. …”
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8476“…Due to its potential close relationship, the Spotted Green Pigeon may hold clues to the historical migration, isolation and morphological evolution of the Dodo and its kindred. …”
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8477“…Our in vivo findings may provide clues for the future therapy strategy for DBA.…”
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8478por Abdullahi, Leila H, Kagina, Benjamin M, Cassidy, Tali, Adebayo, Esther F, Wiysonge, Charles S, Hussey, Gregory D“…Therefore, understanding their knowledge, attitudes and practices towards adolescent vaccination may provide clues on what can be done to improve vaccine uptake among adolescents. …”
Publicado 2014
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8479por Lai, Chooi-May, Yu, Meaghan JT, Brankov, Meliha, Barnett, Nigel L, Zhou, Xiaohuai, Redmond, T Michael, Narfstrom, Kristina, Rakoczy, P Elizabeth“…Although the functional recovery in this model was not as robust as in the dog model, these experiments provided important clues about the long-term physiological benefits of restoration of RPE65 expression in the retina.…”
Publicado 2004
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8480por Evans, Tiffany-Jane, Milne, Elizabeth, Anderson, Denise, de Klerk, Nicholas H., Jamieson, Sarra E., Talseth-Palmer, Bente A., Bowden, Nikola A., Holliday, Elizabeth G., Rudant, Jérémie, Orsi, Laurent, Richardson, Ebony, Lavis, Laura, Catchpoole, Daniel, Attia, John R., Armstrong, Bruce K., Clavel, Jacqueline, Scott, Rodney J.“…The polygenic nature of childhood ALL predisposition together with the timing of environmental triggers may hold vital clues for disease etiology. This study presents results from an Australian GWAS of childhood ALL cases (n = 358) and population controls (n = 1192). …”
Publicado 2014
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