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  1. 8521
    por Xu, Gang, Huang, Jian, Yang, Yong, Yao, Yin-an
    Publicado 2016
    “…CONCLUSIONS: Our transcriptome data provide a comprehensive gene expression profile for flower sex differentiation in Jatropha curcas, as well as new clues and information for further study in this field.…”
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    Transcriptome Analysis of Flower Sex Differentiation in Jatropha curcas L. Using RNA Sequencing
  2. 8522
    “…The identification of 2 new linkage signals in populations of various ethnic origins living in different M. tuberculosis exposure settings provides new clues about the genetic control of human antimycobacterial immunity.…”
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    Major Loci on Chromosomes 8q and 3q Control Interferon γ Production Triggered by Bacillus Calmette-Guerin and 6-kDa Early Secretory Antigen Target, Respectively, in Various Populations
  3. 8523
    “…BACKGROUND: The systemic information enclosed in microarray data encodes relevant clues to overcome the poorly understood combination of genetic and environmental factors in Parkinson’s disease (PD), which represents the major obstacle to understand its pathogenesis and to develop disease-modifying therapeutics. …”
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    Efficient and biologically relevant consensus strategy for Parkinson’s disease gene prioritization
  4. 8524
    “…In addition, we provide clues for planning similar experiments with regard to pool size and the sequencing depth required. …”
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    Rapid gene identification in sugar beet using deep sequencing of DNA from phenotypic pools selected from breeding panels
  5. 8525
    “…Both the similarities and differences between the significance of these loci when compared with significance of loci in studies of populations of European descent underscore the fact that further genetic association of studies in additional populations will provide clues to identify the genetic architecture of CAD across all populations worldwide.…”
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    Genetics of Coronary Artery Disease in Taiwan: A Cardiometabochip Study by the Taichi Consortium
  6. 8526
    “…An assessment of enzyme activity and iron content of these mutants give important clues for understanding the architecture of the active site positioned within the core of the EctC cupin barrel.…”
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    Biochemistry and Crystal Structure of Ectoine Synthase: A Metal-Containing Member of the Cupin Superfamily
  7. 8527
    “…This study contributes to our understanding of the neural basis of restricted interests in ASD and may provide clues toward developing novel interventions. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s11689-016-9149-6) contains supplementary material, which is available to authorized users.…”
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    A functional neuroimaging study of fusiform response to restricted interests in children and adolescents with autism spectrum disorder
  8. 8528
    “…While large amounts of sequencing data are being generated, the associated analysis and interpretation of mutation patterns that may reveal clues about the natural history of cancer present complex and challenging tasks that require advanced bioinformatics skills. …”
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    MutSpec: a Galaxy toolbox for streamlined analyses of somatic mutation spectra in human and mouse cancer genomes
  9. 8529
    por Sariaslan, A, Larsson, H, Fazel, S
    Publicado 2016
    “…These findings highlight the problems of not disentangling common and unique sources of covariance across genetically similar phenotypes as the latter sources may include aetiologically important clues. Clinically, these findings underline the importance of assessing risk of different phenotypes together and integrating interventions for psychiatric disorders, substance misuse, and violence.…”
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    Genetic and environmental determinants of violence risk in psychotic disorders: a multivariate quantitative genetic study of 1.8 million Swedish twins and siblings
  10. 8530
    “…Our data provides important clues about the molecular mechanisms that regulate biomineralization in pearl oyster.…”
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    PfSMAD4 plays a role in biomineralization and can transduce bone morphogenetic protein-2 signals in the pearl oyster Pinctada fucata
  11. 8531
    “…RESULTS: We find that many death certificates coded to garbage codes contain other information that provides strong clues about the valid underlying cause of death. …”
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    Improving the usefulness of US mortality data: new methods for reclassification of underlying cause of death
  12. 8532
    “…The main objective of our study was to describe the epidemiological and diagnosis clues of HA in Mayotte. The secondary objectives were to evaluate the contribution of Real-Time Polymerase Chain Reaction (RT- PCR) for the diagnosis of HA, delineate the characteristics of the local transmission and ascertain the presence of A. cantonensis in Achatina fulica, the potential vector of the disease. …”
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    Angiostrongylus cantonensis Infection on Mayotte Island, Indian Ocean, 2007-2012
  13. 8533
    “…To evaluate the impact of low circulating NK cell counts and to provide some clues to the role of NK cells in natural conditions, we studied a large cohort of patients with common variable immunodeficiency (CVID) included in a multicenter cohort of patients with primary hypogammaglobulinaemia. …”
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    Low Circulating Natural Killer Cell Counts are Associated With Severe Disease in Patients With Common Variable Immunodeficiency
  14. 8534
    “…BACKGROUND: Co-expression networks have been a useful tool for functional genomics, providing important clues about the cellular and biochemical mechanisms that are active in normal and disease processes. …”
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    Exploiting single-cell expression to characterize co-expression replicability
  15. 8535
    “…By deeply analyzing the constructed hypergraph, some hidden clues for better understanding the underlying genetic architecture of complex diseases could be revealed. …”
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    CINOEDV: a co-information based method for detecting and visualizing n-order epistatic interactions
  16. 8536
    “…In this study we examined early stage interaction between R. solani AG1 IA strain and Z. japonica cultivar “Zenith” root by cell ultra-structure analysis, pathogenesis-related proteins assay and transcriptome analysis to explore molecular clues for AG1 IA strain pathogenicity in Z. japonica. …”
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    De novo Transcriptome Analysis of Rhizoctonia solani AG1 IA Strain Early Invasion in Zoysia japonica Root
  17. 8537
    “…Taken together, we gained clues that lead us to hypothesize sRNA-driven DNA methylation and possibly chromatin remodeling during male meiosis in the monocot maize which is in line with and extends previous knowledge.…”
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    Novel Meiotic miRNAs and Indications for a Role of PhasiRNAs in Meiosis
  18. 8538
    “…Understanding their longitudinal evolution and interactions after surgical treatment provides clues to the pathogenesis of cognitive impairment and its reversibility. …”
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    Longitudinal brain structural alterations and systemic inflammation in obstructive sleep apnea before and after surgical treatment
  19. 8539
    “…Two themes, the ability to detect clues and the ability to address concerns, related directly to the overall construct managing patients’ concerns. …”
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    Exploring cultural and linguistic influences on clinical communication skills: a qualitative study of International Medical Graduates
  20. 8540
    “…Finally, our fusion dataset provides powerful clues to decipher the biological activities of domains of unknown function. …”
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    Systematic identification and analysis of frequent gene fusion events in metabolic pathways
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