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8741“…Therefore, our study provides the clues for improving the clinical strategies of osteoporosis, dental implantation or orthodontic treatment.…”
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8742por Knudsen, Kristina B., Berthing, Trine, Jackson, Petra, Poulsen, Sarah S., Mortensen, Alicja, Jacobsen, Nicklas R., Skaug, Vidar, Szarek, Józef, Hougaard, Karin S., Wolff, Henrik, Wallin, Håkan, Vogel, Ulla“…Identification of diameter size and cobalt content as important for MWCNT toxicity provides clues for designing MWCNT, which cause reduced human health effects following pulmonary exposure.…”
Publicado 2018
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8743por Pinto, Pablo, da Silva, Moisés Batista, Moreira, Fabiano Cordeiro, Bouth, Raquel Carvalho, Gobbo, Angélica Rita, Sandoval, Tatiana Vinasco, Ribeiro-dos-Santos, André Mauricio, Vidal, Amanda Ferreira, Barreto, Josafá Gonçalves, Santos, Sidney, Spencer, John Stewart, Salgado, Claudio Guedes, Ribeiro-dos-Santos, Ândrea“…In addition to new findings on leprosy physiopathology, the discovery of relevant piRNAs involved in disease processes in human skin may provide new clues for therapeutic targets, specifically to control nerve damage, a prominent feature of leprosy that has no currently available pharmaceutical treatment.…”
Publicado 2020
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8744por Fang, Lin, Xu, Xin, Li, Ji, Zheng, Feng, Li, Mingzhi, Yan, Jingwei, Li, Yuan, Zhang, Xinhua, Li, Lin, Ma, Guohua, Zhang, Aying, Lv, Fubing, Wu, Kunlin, Zeng, Songjun“…The transcriptome profiles of P. armeniacum seed at different development stages were compared to explore the molecular clues for non-methylated lignin synthesis. Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis showed that a large number of genes associated with phenylpropanoid biosynthesis and phenylalanine metabolism during seed maturation were differentially expressed. …”
Publicado 2020
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8745“…This study will also provide clues for future biomarker studies involving brain diseases.…”
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8746“…Significant suppression of serum miRNA-21 in IA patients may provide diagnostic clues for aneurysm rupture and guide clinical intervention.…”
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8747Comprehensive Analysis of SiNPs on the Genome-Wide Transcriptional Changes in Caenorhabditis eleganspor Liang, Shuang, Duan, Junchao, Hu, Hejing, Zhang, Jingyi, Gao, Shan, Jing, Haiming, Li, Guojun, Sun, Zhiwei“…These data provide abundant clues to understand the molecular mechanisms of SiNPs in C. elegans.…”
Publicado 2020
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8748por Wang, Wei, Liu, Sen, Qiu, Zhihan, He, Miao, Wang, Lanhua, Li, Yuting, Huang, Wenyong“…These findings provide more clues to suggest that choroid alterations play a role in the pathogenesis of DR.…”
Publicado 2020
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8749por Zhao, Jing-Chun, Zhang, Xiu-Hang, Zhang, Nan, Wu, Zhen-Dong, Wang, Jian, Yu, Qing-Hua, Hong, Lei, Shi, Kai, Yu, Jia-Ao“…To make the results objective and convincing, a data analysis was performed relating to demographic characteristics, clinical presentation, predisposing factor, bacterial culture, laboratory and radiographic evaluations, diagnostic clues, management, and complications as well as the clinical course and outcome. …”
Publicado 2020
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8750por Tan, Yanning, Sun, Xuewu, Fang, Baohua, Sheng, Xiabing, Li, Zheli, Sun, Zhizhong, Yu, Dong, Liu, Hai, Liu, Ling, Duan, Meijuan, Yuan, Dingyang“…Our findings provide evidence that cds.71 may act as a mutation hotspot and clues for breeding TGMS lines in a more efficient way.…”
Publicado 2020
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8751por Baillo, Elamin Hafiz, Hanif, Muhammad Sajid, Guo, Yinghui, Zhang, Zhengbin, Xu, Ping, Algam, Soad Ali“…Functionally characterized WRKY genes in Arabidopsis and other species will provide clues for the functional characterization of putative orthologs in sorghum. …”
Publicado 2020
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8752“…Using this tool, we have found critical clues for the transmission route of SARS-CoV-2 which would provide theoretical support for the epidemic control of pathogenic coronaviruses.…”
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8753“…CONCLUSIONS: Taken together, our findings provide the first clues regarding the role of miR-138-5p as a tumor suppressor in ccRCC by directly targeting of TMEM40…”
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8754por Bodelon, Clara, Oh, Hannah, Derkach, Andriy, Sampson, Joshua N., Sprague, Brian L., Vacek, Pamela, Weaver, Donald L., Fan, Shaoqi, Palakal, Maya, Papathomas, Daphne, Xiang, Jackie, Patel, Deesha A., Linville, Laura, Clare, Susan E., Visscher, Daniel W., Mies, Carolyn, Hewitt, Stephen M., Brinton, Louise A., Storniolo, Anna Maria V., He, Chunyan, Chanock, Stephen J., Garcia-Closas, Montserrat, Gierach, Gretchen L., Figueroa, Jonine D.“…We evaluated whether a recently developed polygenic risk score (PRS) based on 313-common variants for breast cancer prediction is related to TDLU involution in the background, normal breast tissue, as this could provide mechanistic clues on the genetic predisposition to breast cancer. …”
Publicado 2020
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8755por Jensen, Barbara, James, Rebecca, Hong, Ying, Omoyinmi, Ebun, Pilkington, Clarissa, Sebire, Neil J., Howell, Kevin J., Brogan, Paul A., Eleftheriou, Despina“…We highlight this case to provide an overview of these genetic mimics of scleroderma, and highlight the molecular pathways that can lead to pathological fibrosis. This may provide clues to the pathogenesis of sporadic juvenile scleroderma, and could suggest novel therapeutic targets.…”
Publicado 2020
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8756por Zeng, Qingpeng, Wang, Bingzhi, Li, Jiagen, Zhao, Jun, Mao, Yousheng, Gao, Yushun, Xue, Qi, Gao, Shugeng, Sun, Nan, He, Jie“…The presence of SNs and SMPs were revealed as independent predictors for STAS, which could offer clinicians clues to identify STAS-positive adenocarcinoma.…”
Publicado 2020
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8757por Wang, Xin-Ru, Wang, Chao, Ban, Fei-Xue, Ghanim, Murad, Pan, Li-Long, Qian, Li-Xin, Liu, Yin-Quan, Wang, Xiao-Wei, Liu, Shu-Sheng“…Our findings provide valuable clues for designing new strategies to block the transmission of insect-vectored plant viruses, particularly plant DNA viruses.…”
Publicado 2020
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8758por Veldsman, Michele, Kindalova, Petya, Husain, Masud, Kosmidis, Ioannis, Nichols, Thomas E.“…The spatial distribution associated with different risk factors may provide important clues as to the pathogenesis and cognitive consequences of WMHs. …”
Publicado 2020
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8759por Shi, Wen, Huang, Xiao-ming, Feng, Yun-lu, Wang, Feng-dan, Gao, Xiao-xing, Jiao, Yang“…The diagnostic timelines of CS patients were reviewed to demonstrate the initial findings of CS at diagnosis, the risk factors associated with diagnostic delay, and potential clues leading to early diagnosis. RESULTS: The median diagnostic delay was 1.75 years (range: 1 month to 29 years, interquartile range: 6.2 years) in 16 enrolled CS patients. …”
Publicado 2020
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8760por Jarrahi, Abbas, Ahluwalia, Meenakshi, Khodadadi, Hesam, da Silva Lopes Salles, Evila, Kolhe, Ravindra, Hess, David C., Vale, Fernando, Kumar, Manish, Baban, Babak, Vaibhav, Kumar, Dhandapani, Krishnan M.“…These unexpected findings may provide important clues regarding the pathological sequela of SARS-CoV-2 infection. …”
Publicado 2020
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