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  1. 8861
    “…We also hypothesize and provide clues that the newer mutations in SARS-CoV2 are unlikely to alter the T-cell mediated immunogenic responses among the studied ethnic populations. …”
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    Does immune recognition of SARS-CoV2 epitopes vary between different ethnic groups?
  2. 8862
    “…The neurological irAEs might be clues to solving the pathomechanism of irAEs.…”
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    Pembrolizumab‐caused polyradiculoneuropathy as an immune‐related adverse event
  3. 8863
    “…This work extends the current knowledge on CO(2) sorption mechanisms providing new clues toward CO(2) sorbent optimization.…”
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    “Hidden” CO(2) in Amine-Modified Porous Silicas Enables Full Quantitative NMR Identification of Physi- and Chemisorbed CO(2) Species
  4. 8864
    “…This study provided valuable clues for functional characterization of ARFs in wheat.…”
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    Key auxin response factor (ARF) genes constraining wheat tillering of mutant dmc
  5. 8865
    “…The detailed analysis of such cases may eventually provide important clues about the respective maldistribution mechanisms and the operative relevance of chromosome 21-specific regions in hyperdiploid leukemias.…”
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    Copy Number Changes and Allele Distribution Patterns of Chromosome 21 in B Cell Precursor Acute Lymphoblastic Leukemia
  6. 8866
    “…Ethnopharmacological approaches provide clues for the search of bioactive compounds. Dryopteris ramosa (Hope) C. …”
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    Iriflophenone-3-C-β-d Glucopyranoside from Dryopteris ramosa (Hope) C. Chr. with Promising Future as Natural Antibiotic for Gastrointestinal Tract Infections
  7. 8867
    “…This study provided some clues for identifying patients who would potentially benefit from ICIs at the somatic genomic level, developing new indications for targeted second-generation sequencing and promoting the development of precision medicine.…”
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    Alterations in TP53 Are a Potential Biomarker of Bladder Cancer Patients Who Benefit From Immune Checkpoint Inhibition
  8. 8868
    “…The time spent on EP visual inspection was significantly shorter when using a device than for inspections without devices, except with the 4500a, risking missing visual clues of samples being SF. The main user errors were the selection of wrong spectrometer reference libraries and wrong user interpretation of PAD results. …”
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    A comparative field evaluation of six medicine quality screening devices in Laos
  9. 8869
    “…A better understanding of this discordance may help differentiate sepsis phenotypes and offer clues to sepsis pathophysiology. Three intensive care unit datasets were utilized. …”
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    Understanding critically ill sepsis patients with normal serum lactate levels: results from U.S. and European ICU cohorts
  10. 8870
    “…It is becoming increasingly clear that differences in miRNA (microRNA) expression signature represent important clues helping us predict a tumor’s response to chemotherapy. …”
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    miRNA Profiling of Hungarian Regressive Wilms’ Tumor Formalin-Fixed Paraffin-Embedded (FFPE) Samples by Quantitative Real-Time Polymerase Chain Reaction (RT-PCR)
  11. 8871
    “…This review provides an overview of the progress in elucidating the role of WNT4 signaling pathway components in cell differentiation in adults, which may provide useful clues for the diagnosis, prevention, and therapy of human diseases.…”
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    Roles and action mechanisms of WNT4 in cell differentiation and human diseases: a review
  12. 8872
    “…SNFR is the major charge-separating module, generating an electrochemical sodium gradient in P. bryantii. Our findings offer clues to the observation that use of fumarate as feed additive does not significantly increase succinate production, or decrease methanogenesis, by the microbial community in the rumen.…”
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    A Sodium-Translocating Module Linking Succinate Production to Formation of Membrane Potential in Prevotella bryantii
  13. 8873
    “…Conclusions: We have provided new clues about the epigenetic changes that occur in ASD, and suggest two potential epigenetic biomarkers that would facilitate the diagnosis of the disorder. …”
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    Analysis of Global and Local DNA Methylation Patterns in Blood Samples of Patients With Autism Spectrum Disorder
  14. 8874
    “…Although the gene signature of a compound perturbation only provides indirect clues of the interacting targets, and the biological networks under different experiment conditions further complicate the situation, the SSGCN model was successfully trained to learn from known compound-target pairs by uncovering the hidden correlations between compound perturbation profiles and gene knockdown profiles. …”
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    Drug target inference by mining transcriptional data using a novel graph convolutional network framework
  15. 8875
    “…We also noted that MYCN inhibition results in reduction in glucose uptake, lactate production, ROS levels and gelatinolytic activity of active-MMP9, explaining a possible mechanism of MYCN in RB. Taking clues from our findings, we tested a combination treatment of RB cells with carboplatin and MYCN inhibitors to find enhanced therapeutic efficacy compared to single drug treatment. …”
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    The Oncogene MYCN Modulates Glycolytic and Invasive Genes to Enhance Cell Viability and Migration in Human Retinoblastoma
  16. 8876
    “…With the integration of multifaceted information, it will shed light on the mechanisms underlying T1D; the provided data and repository has utility in understanding phenotypic disease networks for the potential development of comorbidities in T1D patients as well as the clues for further research on T1D comorbidities.…”
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    Elucidate multidimensionality of type 1 diabetes mellitus heterogeneity by multifaceted information
  17. 8877
    “…This study provided the first acetylomic profiling and acetylation-mediated molecular pathways in human NF-PitNETs, and offered new clues to elucidate the biological functions of protein acetylation in NF-PitNETs and discover novel biomarkers for early diagnosis and targeted therapy of NF-PitNETs.…”
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    Quantitative Acetylomics Revealed Acetylation-Mediated Molecular Pathway Network Changes in Human Nonfunctional Pituitary Neuroendocrine Tumors
  18. 8878
    “…However, history of appendectomy might also give some clues about the course of FMF in the adulthood. This study was to determine whether the history of appendectomy help to anticipate disease course of FMF in the adulthood. …”
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    Appendectomy history is associated with severe disease and colchicine resistance in adult familial Mediterranean fever patients
  19. 8879
    “…Besides, the coexistence of professional phagocytes and non-professional phagocytes as well as their interplay in the MEM provides new clues for deciphering the underlying pathogenic mechanisms of AOM.…”
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    Single-Cell Transcriptome Profiling Identifies Phagocytosis-Related Dual-Feature Cells in A Model of Acute Otitis Media in Rats
  20. 8880
    “…Gene ontology enrichment analysis revealed that the protein changes of the gut–brain axis were involved in a variety of biological functions, including metabolic process and inflammatory response, in which energy metabolism is the core change of the protein network. Our data provide clues for future studies in the gut–brain axis on protein level and deepen the understanding of how gut microbiota cause depression-like behaviors.…”
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    Proteomics analysis of the gut–brain axis in a gut microbiota-dysbiosis model of depression
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