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  1. 9081
    “…Thus, the key pathways, DEGs, and hub genes identified in this study can provide important clues to elucidate the molecular mechanisms involved in MMTV replication, escape from cellular anti-viral response, and potential to cause cell transformation. …”
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    Global Down-regulation of Gene Expression Induced by Mouse Mammary Tumor Virus (MMTV) in Normal Mammary Epithelial Cells
  2. 9082
    “…CONCLUSIONS: These findings may provide clues for the design of effective interventions to promote preventive dental care use and improve oral health status.…”
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    Associations of health literacy with dental care use and oral health status in Japan
  3. 9083
    “…Our study provides new information on the molecular mechanisms used by NK exosomes to exert anti-tumor-activity and offers new clues to integrate cancer treatments with NK exosomes.…”
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    MicroRNA analysis of Natural Killer cell-derived exosomes: the microRNA let-7b-5p is enriched in exosomes and participates in their anti-tumor effects against pancreatic cancer cells
  4. 9084
    “…Our results provide evidence of the cross talk of autophagy and apoptosis in U. virens and give clues for studying other phytopathogenic fungi. IMPORTANCE Ustilaginoidea virens causes destructive panicle disease in rice, significantly threatening agricultural production. …”
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    UvATG6 Interacts with BAX Inhibitor 1 Proteins and Plays Critical Roles in Growth, Conidiation, and Virulence in Ustilaginoidea virens
  5. 9085
    “…CONCLUSION: Our study found several meaningful correlations between osteoporosis and schizophrenia, especially regarding laboratory measures, which may provide new clues to identifying or preventing osteoporosis in clinical patients. …”
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    Risk factors for osteoporosis in chronic schizophrenia on long-term treatment with antipsychotics: a cross-sectional study
  6. 9086
    “…CONCLUSIONS: In addition to established risk factors, elevated IgM levels, positive ACA, and high ANA titre with cytoplasmic pattern provide clues to clinicians for the early screening and diagnosis of PBC in patients with SS.…”
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    Laboratory risk factors for coexistent primary biliary cholangitis in patients with Sjögren’s syndrome: a retrospective study
  7. 9087
    “…In addition, WES provided clues in evaluating potential risks of gene variants on fatal clinical outcomes, and the nonsense and frameshift variants of ALPK3 were related to adverse clinical outcomes in HCM patients, which required implantable cardioverter defibrillator (ICD) timely.…”
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    A novel compound heterozygous variant in ALPK3 induced hypertrophic cardiomyopathy: a case report
  8. 9088
    “…In conclusion, our study provides new clues to uncover the causative factors of AQP4-IgG(+) NMOSD and provides a theoretical foundation for treating and monitoring the disease.…”
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    Immune Repertoire Profiling Reveals Its Clinical Application Potential and Triggers for Neuromyelitis Optica Spectrum Disorders
  9. 9089
    “…The signature of cuproptosis-related genes presents new clues for exploring the roles of neuronal death in TLE. …”
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    Cuproptosis-related genes signature and validation of differential expression and the potential targeting drugs in temporal lobe epilepsy
  10. 9090
    “…CONCLUSION: Thus, monocyte miRNA signatures provide pathological clues for altered monocyte function, drug resistance, and disease severity. …”
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    Downregulation of monocyte miRNAs: implications for immune dysfunction and disease severity in drug-resistant tuberculosis
  11. 9091
    “…Our findings reveal a close relationship between CGs and the immune microenvironment of diseases. This provides clues for further exploring the common mechanism and interaction between the two diseases.…”
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    Comprehensive bioinformatics analysis reveals the crosstalk genes and immune relationship between the systemic lupus erythematosus and venous thromboembolism
  12. 9092
    “…In summary, we developed a more detailed cytokine and chemokine map of peripheral specific CD8(+) T cell and NK cell subsets, which revealed disrupted secretory function in patients with PD and provided unique clues for further mechanistic exploration.…”
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    Cytokine and chemokine map of peripheral specific immune cell subsets in Parkinson’s disease
  13. 9093
    “…These results suggest an unexpected evolutionary relationship between the P. gulae - P. gingivalis duo and P. loveana, showing more clues about the origin of the role of those organisms in periodontitis.…”
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    Phylogenomic analysis of the Porphyromonas gingivalis - Porphyromonas gulae duo: approaches to the origin of periodontitis
  14. 9094
    “…In this study, to obtain further clues on CASQ1 functions, we characterized the ultrastructural alterations and examined the maturation of calcium release units, as well as the involvement of different junctional proteins in juxtaposition of the membrane system in skeletal muscle fibers during development from birth to the adult age. …”
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    Structural Adaptation of the Excitation–Contraction Coupling Apparatus in Calsequestrin1-Null Mice during Postnatal Development
  15. 9095
    “…Conclusion Patient-related factors such as gender, bilateral presentation, and the presence of hypertension and radiological factors such as the presence of heterogenous subtype and a significant midline shift are clues toward a higher chance of recurrence.…”
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    Recurrent Subdural Hematoma: An Institutional Experience
  16. 9096
    “…Conclusion  This MR analysis demonstrated no significant causal associations of type 1 and type 2 diabetes with VTE in both directions, in conflict with previous observational studies reporting positive association, which provided clues for understanding the underlying pathogenesis of diabetes and VTE.…”
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    The Causality between Diabetes and Venous Thromboembolism: A Bidirectional Two-Sample Mendelian Randomization Study
  17. 9097
    “…Our data suggest that Hmo1, but not Hho1, possesses some functionality similar to that of linker histone in Saccharomyces cerevisiae, even though some properties of Hmo1 differ from those of a canonical linker histone H1. Our study provides clues for the linker histone H1 in budding yeast and provides insights into the evolution and diversity of histone H1 across eukaryotes. …”
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    Single-molecule study reveals Hmo1, not Hho1, promotes chromatin assembly in budding yeast
  18. 9098
    “…Double ANCA-positive AAV cases are genetically similar to PR3-ANCA-positive cases, providing clues to the clinical follow-up and treatment of these patients.…”
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    Stratified genetic analysis reveals sex differences in MPO-ANCA-associated vasculitis
  19. 9099
    “…CONCLUSION: This study reveals the potential common pathogenesis between MAFLD and COVID-19, providing novel clues for future research and treatment of MAFLD and severe acute respiratory syndrome coronavirus 2 infection.…”
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    Demonstration of the impact of COVID-19 on metabolic associated fatty liver disease by bioinformatics and system biology approach
  20. 9100
    “…CONCLUSIONS: DA represents a controversial diagnostic entity that incorporates elements of psychogenic fugue states, repressed memory, traumatic amnesia, and conversion. Some clues in the history such as psychological traumas can support a diagnosis of DA rather than medical causes. …”
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    Exploring the limits of generalized dissociative amnesia: A case report
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