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  1. 9521
    “…The study also offered some important insights into the references and clues for the genetic breeding of yaks.…”
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    Copy Number Variation of the SOX6 Gene and Its Associations with Growth Traits in Ashidan Yak
  2. 9522
    “…Our study identified a series of miRNA that were differentially expressed between RT good responders and poor responders, providing useful clues for further functional assays to demonstrate a possible regulatory role in radioresistance.…”
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    Improving the prediction for the response to radiotherapy of clinical tumor samples by using combinatorial model of MicroRNA expression
  3. 9523
    “…These results could provide important clues regarding the pathogenesis of orthopnea. Spearman’s correlation coefficients between the inspiratory airway volume on CT and forced vital capacity and forced expiratory volume in 1 s on PFT were numerically higher in the standing position than in the supine position (0.673 vs. 0.659 and 0.669 vs. 0.643, respectively); however, no statistically significant differences were found. …”
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    Comparison of inspiratory and expiratory airway volumes and luminal areas among standing, sitting, and supine positions using upright and conventional CT
  4. 9524
    “…Our findings establish a preclinical proof-of-concept for combating CRC using combined multi-target treatment with PB-020 and clinical anticancer drugs, which may provide useful clues for clinical trials to evaluate the efficacy and safety of these drug combinations in CRC patients.…”
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    The Novel IGF-1R Inhibitor PB-020 Acts Synergistically with Anti-PD-1 and Mebendazole against Colorectal Cancer
  5. 9525
    “…CONCLUSION: Our study found evidence that gut microbiota is causally associated with longevity, or vice versa, providing novel clues for understanding the roles of gut microbiota in aging development. …”
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    Association between gut microbiota and longevity: a genetic correlation and mendelian randomization study
  6. 9526
    “…These findings are pivotal to provide clues for subsequent development of targeted methods to combat NRCS-A and to stop its dissemination.…”
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    Environmental Persistence of Staphylococcus capitis NRCS-A in Neonatal Intensive Care Units: Role of Biofilm Formation, Desiccation, and Disinfectant Tolerance
  7. 9527
    “…Using transcriptome sequencing, we determined the whole set of genes regulated by Fts2 and identified the major targets of Fts2 repression, which provide clues to the mechanism by which Fts2 represses filamentation. …”
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    The Zinc Finger Transcription Factor Fts2 Represses the Yeast-to-Filament Transition in the Dimorphic Yeast Yarrowia lipolytica
  8. 9528
    “…Thus, screening the key genes for W absence would provide clues for producing high female ratio or all female fry, benefiting the tongue sole industry. …”
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    Transcriptomic Analysis Revealed Candidate Genes Involved in Pseudomale Sperm Abnormalities in Chinese Tongue Sole (Cynoglossus semilaevis)
  9. 9529
    “…Our study aims to determine the exact role of PA0715 in cell physiology and bacterial pathogenicity, providing important clues for antibiotic development. PATIENTS AND METHODS: The shuttle vector pHERD20T containing an arabinose inducible promoter was used to construct the CRISPRi system. …”
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    CRISPRi-Mediated Gene Suppression Reveals Putative Reverse Transcriptase Gene PA0715 to Be a Global Regulator of Pseudomonas aeruginosa
  10. 9530
    “…In summary, we identified two G × G interactions at both the epigenetic and transcriptional levels, and our findings may provide potential clues for precision treatment of NSCLC.…”
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    A trans‐omics assessment of gene–gene interaction in early‐stage NSCLC
  11. 9531
    “…Additional aggressive imaging features that may be valuable clues to the diagnosis can be identified by CT or MRI. …”
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    CT and MRI features of hepatic epithelioid haemangioendothelioma: a multi-institutional retrospective analysis of 15 cases and a literature review
  12. 9532
    “…CONCLUSION: The cytologic characteristics of the tumor can provide sufficient clues for PEComa diagnosis, which includes loosely cohesive, epithelioid morphology with abundant clear or eosinophilic cytoplasm, low-grade nuclear atypia, cytoplasmic melanin pigments. …”
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    Perivascular epithelioid cell tumor of the uterine cervix identified on the liquid-based cytology: a case report
  13. 9533
    “…Therefore, the key genes associated with sieve pigments will provide clues for the production of goldfish with a diversity of skin tones, benefiting the goldfish industry. …”
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    Comprehensive Transcriptome Analysis of Different Skin Colors to Evaluate Genes Related to the Production of Pigment in Celestial Goldfish
  14. 9534
    “…ABSTRACT: Various microfossils from the early Cambrian provide crucial clues for understanding the Cambrian explosion and the origin of animal phyla. …”
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    Recognition of Rare Microfossils Using Transfer Learning and Deep Residual Networks
  15. 9535
    “…CONCLUSIONS: Our findings provide new insights into GIT microbial organization and function in dairy cattle by GIT regions and diet regimes, which offers clues for improving animal production and health in the future. …”
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    The gastrointestinal microbiome in dairy cattle is constrained by the deterministic driver of the region and the modified effect of diet
  16. 9536
    “…ABSTRACT: Population genetic studies can reveal clues about the evolution of adaptive strategies of aphid species in agroecosystems and demonstrate the influence of environmental factors on the genetic diversity and gene flow among aphid populations. …”
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    Analysis of the Genetic Diversity of Two Rhopalosiphum Species from China and Europe Based on Nuclear and Mitochondrial Genes
  17. 9537
    “…In-depth studies on the regulatory mechanism of critical protein degradation regulators, including E3 ubiquitin ligases, deubiquitylating enzymes (DUBs), and chaperones, are expected to provide precise clues for developing targeting strategies and reducing side effects. …”
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    Protein degradation: expanding the toolbox to restrain cancer drug resistance
  18. 9538
    “…Post-TSS subarachnoid hemorrhage and hemiparesis may be important clues indicating CVS and infarction. There is limited evidence in the literature regarding post-TSS CVS surveillance and treatment strategies which could have an impact on clinical decisions.…”
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    Cerebral vasospasm following subarachnoid hemorrhage: a rare complication after transsphenoidal surgery for pituitary macroadenoma
  19. 9539
    “…This study’s findings not only confirm the plants’ traditional claim but also provide clues for further investigation of the active principles of this plant for the development of effective and safe analgesic and anti-inflammatory drugs.…”
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    Analgesic and Anti-Inflammatory Effects of 80% Methanol Extract and Solvent Fractions of the Leaves of Vernonia auriculifera Hiern. (Asteraceae)
  20. 9540
    “…We analyzed the cis‐regulatory elements (CREs) in promoters of isoprene‐responsive genes and the corresponding transcription factors binding these promoter elements to obtain clues about the transcription factors and other proteins involved in isoprene signaling. …”
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    Characterization of promoter elements of isoprene‐responsive genes and the ability of isoprene to bind START domain transcription factors
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