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  1. 9941
    “…The clinical picture, laboratory and radiograph alterations are important clues for those patients and are usually characterized by polyarthralgia, renal tubular dysfunction and mineralization defects. …”
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    Adefovir dipivoxil induced hypophosphatemic osteomalacia in chronic hepatitis B: a comparative study of Chinese and foreign case series
  2. 9942
    “…CONCLUSION: Findings in this study demonstrated that ZIKV infection activates ER stress in neural cells. The results offer clues to further study the mechanism of neuropathogenesis caused by ZIKV infection. …”
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    ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells
  3. 9943
    “…These findings suggest the safety of biomedical applications employing AuNPs during pregnancy is strongly influenced by fetal maturity and gestational age at exposure and provide the clues for AuNPs safe application period in pregnancy. …”
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    Murine exposure to gold nanoparticles during early pregnancy promotes abortion by inhibiting ectodermal differentiation
  4. 9944
    “…Our study provides new insights into the pathogenesis of HIV and AIDS and clues for the therapeutic strategies for anti-retroviral administration. …”
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    An integrative genomic analysis of transcriptional profiles identifies characteristic genes and patterns in HIV-infected long-term non-progressors and elite controllers
  5. 9945
    “…Our findings give genetic clues for further rational optimization of K. marxianus’ ethanol production, and also partly confirm the positively correlated relationship between yeast’s ethanol tolerance and production. …”
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    Kluyveromyces marxianus developing ethanol tolerance during adaptive evolution with significant improvements of multiple pathways
  6. 9946
    “…Understanding these genotype-phenotype associations may provide further insight into the pathogenic nature of the mutations, as well as offer clues for developing new therapeutic targets.…”
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    Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry
  7. 9947
    “…Several steps can be taken to identify results that may reflect the presence of interfering factors including: 1) discrepancies between current values and previous results using the same methods; 2) clues from the clinical setting; 3) the pattern of discrepant and non-discrepant thyroid profile results (1,2) Clinical case: A 67-year-old woman admitted with generalized muscle weakness for one week. …”
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    SAT-612 An Anti-Idiotype Antibody to T3 Measurements: A Misleading Cause of Inappropriate TSH Secretion
  8. 9948
    “…Our findings provide important clues not only for understanding the molecular mechanisms of cold stress in plants but also for introducing cold hardiness into M. wufengensis. …”
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    De novo transcriptome sequencing and gene expression profiling of Magnolia wufengensis in response to cold stress
  9. 9949
    “…These findings may provide important clues that the tolerogenic cascade in MAH-infected DCs induced by TLR 4 signaling can alter host immune response.…”
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    Infection of Dendritic Cells With Mycobacterium avium subspecies hominissuis Exhibits a Functionally Tolerogenic Phenotype in Response to Toll-Like Receptor Agonists via IL-10/Cox2/PGE2/EP2 Axis
  10. 9950
    “…This research provides some clues to understand CHI’s differential biochemical functional characterization involving in flavonoid pathway. …”
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    Integrating molecular characterization and metabolites profile revealed CtCHI1’s significant role in Carthamus tinctorius L.
  11. 9951
    “…Understanding the reasons underlying these trends may provide valuable clues for developing more targeted therapies and public health strategies. …”
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    Temporal Trends and Patterns in Mortality After Incident Heart Failure: A Longitudinal Analysis of 86 000 Individuals
  12. 9952
    “…These results provide constructive clues for further functional investigation and epigenetic mechanism dissection of SET-containing proteins in orchids.…”
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    Genome-wide identification and expression profiling of SET DOMAIN GROUP family in Dendrobium catenatum
  13. 9953
    “…A novel breast cancer immunotyping and a new prognostic model based on tumour-infiltrating immune cell subsets have been established, aiming to provide new clues regarding prognostic prediction and precision therapy for breast cancer. …”
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    Tumour-Infiltrating Immune Cell-Based Subtyping and Signature Gene Analysis in Breast Cancer Based on Gene Expression Profiles
  14. 9954
    “…CONCLUSION: This is the first study revealing lncRNA-associated ceRNA network during odontogenic differentiation of hDPSCs using microarray, and it could provide clues to explore the mechanism of action at the RNA-RNA level as well as novel treatments for dentin regeneration based on stem cells.…”
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    Genome-wide identification of long noncoding RNAs and their competing endogenous RNA networks involved in the odontogenic differentiation of human dental pulp stem cells
  15. 9955
    “…The comparative qualitative and quantitative immunorecognition profile of the Brazilian pentabothropic antivenom toward the venom toxins of B. brazili and B. jararaca (the reference venom for assessing the bothropic antivenom's potency in Brazil), provides clues about the proper use of the Brazilian antibothropic polyvalent antivenom in the treatment of bites by the Brazil’s lancehead.…”
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    Venomics and antivenomics of the poorly studied Brazil’s lancehead, Bothrops brazili (Hoge, 1954), from the Brazilian State of Pará
  16. 9956
    “…We hypothesize that the perinatal change in deiodinase expression is controlled by a developmental clock rather than environmental clues and therefore have limited capacity function as compensatory mechanisms in response to low TH during development. …”
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    SAT-448 Limited Adaptive Response by Deiodinase Enzymes in the Perinatal Hypothyroid Cochlea
  17. 9957
    “…CONCLUSIONS: Adequate information about DDIs and clues about how to manage ART when PLHIV are using illicit drugs could reduce the negative effects of such interactions and improve ART adherence and QoL.…”
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    Drug use and antiretroviral therapy (ART) interactions: a qualitative study to explore the knowledge, beliefs, adherence, and quality of life of people living with HIV taking ART and illicit drugs
  18. 9958
    “…Although the platelet count may provide clues regarding the severity of liver disease, there are currently no available data supporting the utility of the platelet count to evaluate the degree of liver injury in patients with chronic hepatitis B virus (HBV) infection. …”
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    Platelet count is closely associated with the severity of liver injury in patients with chronic hepatitis B virus infection: A cross-sectional study
  19. 9959
    “…This study might facilitate a better understanding of gene function for the ER2566 strain under external burden and provided more clues to engineer bacteria for biotechnological applications.…”
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    Genome re-sequencing and reannotation of the Escherichia coli ER2566 strain and transcriptome sequencing under overexpression conditions
  20. 9960
    “…CONCLUSIONS: Care provision for MRKHS patients is largely characterized by delayed proper diagnosis and in part, by inappropriate treatment attempts; there are also indications of regional differences. Anamnestic clues such as an asymptomatic amenorrhea or renal abnormalities of unclear origin still fail to result early enough in referral to a center on the basis of suspected MRKHS diagnosis. …”
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    Rare genital malformations in women’s health research: sociodemographic, regional, and disease-related characteristics of patients with Mayer-Rokitansky-Küster-Hauser syndrome
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