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  1. 10061
    “…We provided fresh molecular clues concerning the antiproliferative effect of CIGB-300 in two relevant AML backgrounds. …”
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    Gene expression profiling unveils the temporal dynamics of CIGB-300-regulated transcriptome in AML cell lines
  2. 10062
    “…Our findings highlight the complicated and diverse associations between an obesity-related DP and cancers and provide clues for future research directions. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12916-023-02955-y.…”
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    Associations between an obesity-related dietary pattern and incidence of overall and site-specific cancers: a prospective cohort study
  3. 10063
    “…This study offers valuable clues into the evolution, function, transcriptional activity and epigenetic regulation of LTR-RTs in Fabaceae genomes. …”
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    Lineage-specific amplification and epigenetic regulation of LTR-retrotransposons contribute to the structure, evolution, and function of Fabaceae species
  4. 10064
    “…OBJECTIVE: An important motivation for this study was to investigate transdiagnostic clues that could ultimately be used for mental health outreach. …”
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    Emotional Expression on Social Media Support Forums for Substance Cessation: Observational Study of Text-Based Reddit Posts
  5. 10065
    “…Driving simulator performance was significantly associated with results of select FSTs (eg, ≥2 clues on One Leg Stand was associated with impairment on the simulator: odds ratio, 3.09; 95% CI, 1.63-5.88; P < .001). …”
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    Evaluation of Field Sobriety Tests for Identifying Drivers Under the Influence of Cannabis: A Randomized Clinical Trial
  6. 10066
    “…In conclusion, we found a key difference in virulence proteins and pathways in the outer membrane vesicles of F. nucleatum between the tumor microenvironment pH and normal intestinal pH, which provides new clues for the prevention and treatment of colorectal cancer. …”
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    Quantitative Proteomic Analysis of Outer Membrane Vesicles from Fusobacterium nucleatum Cultivated in the Mimic Cancer Environment
  7. 10067
    “…Methods: The primary aim of this study was to identify valuable clinical and dermoscopic clues to enhance the detection of SDMs. To achieve this objective, we conducted a comprehensive retrospective analysis, including forty SDMs with a diameter of 5 mm or less. …”
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    Exploring Small-Diameter Melanomas: A Retrospective Study on Clinical and Dermoscopic Features
  8. 10068
    “…Some proliferative neoplastic cell may educate macrophages, which promotes tumorigenesis possibly through the MIF-CD74 interaction. It provides novel clues for future potential therapeutic avenues. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12967-023-04445-4.…”
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    Decoding meningioma heterogeneity and neoplastic cell—macrophage interaction through single-cell transcriptome profiling across pathological grades
  9. 10069
    “…WIDER IMPLICATIONS OF THE FINDINGS: The abundance of malonate, 5-oxyproline, and erythronate in CC was significantly higher in COCs ultimately establishing pregnancy, providing clues on the pathways required for oocyte competence. …”
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    Metabolomics analysis of human cumulus cells obtained from cumulus–oocyte complexes with different developmental potential
  10. 10070
    “…Although molecular subtyping is expected to offer important clues for precision treatment of PCA, there is currently a shortage of dependable and effective molecular typing methods available for clinical practice. …”
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    Integrative multi-omics analysis unveils stemness-associated molecular subtypes in prostate cancer and pan-cancer: prognostic and therapeutic significance
  11. 10071
    “…Combined examination of the chest, abdomen, and pelvis was favored (34.8%, n = 129/371) in cases without clinical clues of an infection source. A time window of ≥ 1–6 h was preferred for both CT examinations (53.9%, n = 200/371) and CT-guided interventions (59.3%, n = 220/371) in patients with sepsis. …”
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    Interdisciplinary perspectives on computed tomography in sepsis: survey among medical doctors at a large university medical center
  12. 10072
    “…CONCLUSIONS: In summary, the miR-182-5p-CHL1/MITF and miR-338-3p-NOVA1 pathway interactions and decreased infiltration of M1 macrophages and resting mast cells may provide novel clues to the pathogenesis of DFU. TRIAL REGISTRATION: The clinical trial included in this study was registered in the Chinese Clinical Trial Registry (ChiCTR2200066660) on December 13, 2022. …”
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    Identifying potential pathogenesis and immune infiltration in diabetic foot ulcers using bioinformatics and in vitro analyses
  13. 10073
    “…Moreover, there must also be clues to autoimmunising mechanisms/cell types in the hierarchy of preferences for IFN-ω, IFN-α8, IFN-α2, and IFN-β and IFN-λ1.…”
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    Anti-Interferon Autoantibodies in Autoimmune Polyendocrinopathy Syndrome Type 1
  14. 10074
    “…CONCLUSIONS: In the absence of diagnostic testing during an influenza A(H5N1) epizootic, a few epidemiologic, clinical, and laboratory findings might provide clues to help target H5N1 control efforts. Severe human influenza and H5N1 cases were clinically similar, and both would benefit from early antiviral treatment.…”
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    A Comparison of Clinical and Epidemiological Characteristics of Fatal Human Infections with H5N1 and Human Influenza Viruses in Thailand, 2004–2006
  15. 10075
    “…Co-expression analysis using an available soybean microarray and Illumina sequencing data provides clues for functional annotation of these enzymes. …”
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    Whole genome co-expression analysis of soybean cytochrome P450 genes identifies nodulation-specific P450 monooxygenases
  16. 10076
    “…Our results improve the current knowledge of genetic variants underlying inflammation and provide novel clues for the understanding of the molecular mechanisms regulating this complex process.…”
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    A Genome-Wide Association Scan on the Levels of Markers of Inflammation in Sardinians Reveals Associations That Underpin Its Complex Regulation
  17. 10077
    “…This work may provide new clues into the molecular mechanisms behind pediatric anaplastic histology WT. …”
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    Analyzing the gene expression profile of anaplastic histology Wilms’ tumor with real-time polymerase chain reaction arrays
  18. 10078
    por Zhang, Yuji
    Publicado 2015
    “…While network data usually constitute only static network maps, integrating them with time course gene expression information can provide clues to the dynamic features of these networks and unravel the mechanistic driver genes characterizing cellular responses. …”
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    Network analysis reveals stage-specific changes in zebrafish embryo development using time course whole transcriptome profiling and prior biological knowledge
  19. 10079
    “…Thus, the transcription of certain gene families is consistently affected by ivermectin ingestion, and may provide important clues to ivermectin’s broad effects on malaria vectors. …”
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    Age and prior blood feeding of Anopheles gambiae influences their susceptibility and gene expression patterns to ivermectin-containing blood meals
  20. 10080
    “…These results provide novel clues for a rational intervention strategy that targets rosetting. …”
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    Functional analysis of monoclonal antibodies against the Plasmodium falciparum PfEMP1-VarO adhesin
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