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  1. 10181
    “…The main objectives were to extract symptoms, classify severity of illness, compare therapy effectiveness, provide psychopathological clues, and challenge the current nosography. Medical records and social media were the 2 major data sources. …”
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    Machine Learning and Natural Language Processing in Mental Health: Systematic Review
  2. 10182
    “…All these provide important clues for new biomarkers and therapeutic targets. …”
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    Exploring new targets for the treatment of hepatitis-B virus and hepatitis-B virus-associated hepatocellular carcinoma: A new perspective in bioinformatics
  3. 10183
    “…Future studies based on these epigenetic clues could promote understanding of the mechanisms of osteogenic differentiation of hASCs. …”
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    Transcriptome-wide m(6)A methylome during osteogenic differentiation of human adipose-derived stem cells
  4. 10184
    “…The combination of different approaches offers new clues regarding the assessment of bacterial communities in soils cultivated with cocoa in soils with elevated Cd content in Colombia, and the ecological role and interplay of soil components and bacterial communities that contribute to modulate the effect of bioaccumulation in products.…”
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    Theobroma cacao L. agricultural soils with natural low and high cadmium (Cd) in Santander (Colombia), contain a persistent shared bacterial composition shaped by multiple soil variables and bacterial isolates highly resistant to Cd concentrations
  5. 10185
    por Lei, Yuqi, Xu, Songhua, Zhou, Linyun
    Publicado 2021
    “…Effective and timely mining and utilization of such content can continuously provide valuable firsthand clues for enhancing the situational awareness of health providers and policymakers.…”
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    User Behaviors and User-Generated Content in Chinese Online Health Communities: Comparative Study
  6. 10186
    “…CONCLUSIONS: The findings depicted a landscape of genomic methylation and transcriptome changes of chondrocytes after T-2 toxin exposure and suggested that dysfunction of MAPK pathway may play important roles in the chondrocytes damage induced by T-2 toxin, which could provide new clues for understanding the potential biological mechanism of KBD cartilage damage induced by T-2 toxin. …”
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    An integrative analysis of DNA methylation and transcriptome showed the dysfunction of MAPK pathway was involved in the damage of human chondrocyte induced by T-2 toxin
  7. 10187
    “…Therefore, it is plausible to suggest that deeper DENV genetic information analysis may bring new clues about genetic markers linked to severe illness. …”
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    Using amino acids co-occurrence matrices and explainability model to investigate patterns in dengue virus proteins
  8. 10188
    “…Deeply phenotyped cohort data can reveal physiological changes associated with genetic risk for AD across an age spectrum that may provide clues to the biology of the disease. We utilized over 2000 high-quality quantitative measurements obtained from blood of 2831 cognitively normal adult clients of a consumer-based scientific wellness company, each with CLIA-certified whole-genome sequencing data. …”
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    Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90
  9. 10189
    “…The variation in the neuropathologic outcomes in individuals with and without LOC may provide clues to potential mechanisms, diagnoses, and management in persons with TBI.…”
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    Association of Traumatic Brain Injury With and Without Loss of Consciousness With Neuropathologic Outcomes in Community-Dwelling Older Persons
  10. 10190
    “…Our results provide important clues for dissecting calcium regulated gene expression networks in response to drought and salt stresses in rice. …”
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    OsOSCA1.1 Mediates Hyperosmolality and Salt Stress Sensing in Oryza sativa
  11. 10191
    “…High throughput Magnetic Resonance (MR) imaging has shown the potential to decipher GB heterogeneity, including pathologic and genomic clues. However, whether distinct GB immune contextures can be deciphered at an imaging scale is still elusive, leaving unattained the non-invasive achievement of prognostic and predictive biomarkers. …”
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    Integrated MRI–Immune–Genomic Features Enclose a Risk Stratification Model in Patients Affected by Glioblastoma
  12. 10192
    “…Our findings better reflected the characteristics of high-risk populations, thus contributing to the development of timely and effective intervention strategies, and providing clues for etiological research. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40249-022-01009-4.…”
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    Age–period–cohort analysis of pulmonary tuberculosis reported incidence, China, 2006–2020
  13. 10193
    “…CONCLUSIONS: In summary, our work provides novel insights into the tumor heterogeneity of NSCLC in terms of the identification of prevalent mixed-lineage subpopulations of cancer cells with combined signatures of SCC, ADC, and NET and offers clues for potential treatment strategies in these patients. …”
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    Molecular profiling of human non-small cell lung cancer by single-cell RNA-seq
  14. 10194
    “…The results will facilitate future functional characterization of individual citrus CBLs and CIPKs under specific stresses and provide clues for the clarification of cold tolerance and disease susceptibility mechanisms in corresponding citrus cultivars. …”
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    Evolution, gene expression, and protein‒protein interaction analyses identify candidate CBL-CIPK signalling networks implicated in stress responses to cold and bacterial infection in citrus
  15. 10195
    por Zhang, Hao, Feng, Ting
    Publicado 2022
    “…The results of this study provide a valuable basis for exploring the mechanisms of ion channel genes in COVID-19 and clues for developing therapeutic strategies for COVID-19.…”
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    Network-Based Data Analysis Reveals Ion Channel-Related Gene Features in COVID-19: A Bioinformatic Approach
  16. 10196
    por Das, Kuladeep, Sanyal, Kaustuv
    Publicado 2022
    “…Further in vivo commensalism experiments in mice will provide important clues on the role of this enzyme in C. albicans’s ability in gut colonization.…”
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    P330 Role of a D-amino acid oxidase (DAO) in an efficient human commensal Candida albicans
  17. 10197
    “…Comparing crucial aspects of the crises’ anatomies the article adds to the understanding of the way multilevel, cross-sectional, hybrid governance and planning respond to concurrent crises, thereby also offering clues for action in other geopolitical contexts. …”
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    Governance and planning in a ‘perfect storm’: Securitising climate change, migration and Covid-19 in Sweden
  18. 10198
    “…Moreover, we show that detection of transient mutations in currently circulating variants can give valuable clues to signature mutations of future VOC. Here we suggest six such mutations, that we detected frequently in the Delta variant during 2021. …”
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    SARS-CoV-2 variants of concern and spike protein mutational dynamics in a Swedish cohort during 2021, studied by Nanopore sequencing
  19. 10199
    “…These findings provide mechanistic clues into the role of ncRNA in the prenatal BPA-induced lipid accumulation and oxidative stress in the liver and muscle, contributors to metabolic dysfunction observed in this female sheep model of gestational BPA exposure. …”
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    RF22 | PMON11 Non-coding RNA Signatures of Prenatal BPA Exposure in Liver and Muscle of Female Sheep
  20. 10200
    “…Diagnosis may be difficult in pre-menopausal women with high oestrogen and variable FSH levels but in men, the unusually high gonadotrophins give the clues for diagnosis. CLINICAL CASE: We present the case of a 37-year-old Caucasian male with clinical manifestations of an FSH-secreting pituitary macroadenoma. …”
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    RF01 | PMON77 Low Libido Despite High Testosterone Levels in a Man With FSH-Secreting Pituitary Macroadenoma
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