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  1. 10201
    “…Continued follow-up and detailed physical exam to check for clues such as hypertension, striae, buffalo hump, and bruising can lead to unmasking a secondary etiology. …”
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    PMON315 Hyperglycemia Dilemma: Concomitant Type 1 Diabetes Mellitus and Cushing's disease
  2. 10202
    “…CONCLUSIONS: Our findings suggest that the rs1804506 polymorphism in miR-17-92 cluster binding sites contributes to the susceptibility of ESCC, which might provide new clues and scientific evidence for the etiology and biomarkers for the prevention and treatment of ESCC. …”
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    Genetic variant in miR-17-92 cluster binding sites is associated with esophageal squamous cell carcinoma risk in Chinese population
  3. 10203
    Tabla de Contenidos: “…Canyon country parklands--v. 68. Clues to america's past--v. 69. Discovering man's past in the americas--v. 70. …”
    Libro
    The National Geographic Society
  4. 10204
    “…Metabolomic profiling provides clues to metabolic alterations beyond clinical definition. …”
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    Cardiovascular risk of metabolically healthy obesity in two european populations: Prevention potential from a metabolomic study
  5. 10205
    “…Our findings might offer novel key clues for the precise management of PDAC and important evidence for future targeted trial design. …”
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    The suppressive efficacy of THZ1 depends on KRAS mutation subtype and is associated with super‐enhancer activity and the PI3K/AKT/mTOR signalling in pancreatic ductal adenocarcinoma: A hypothesis‐generating study
  6. 10206
    por Porcu, Eleonora, Medici, Marco, Pistis, Giorgio, Volpato, Claudia B., Wilson, Scott G., Cappola, Anne R., Bos, Steffan D., Deelen, Joris, den Heijer, Martin, Freathy, Rachel M., Lahti, Jari, Liu, Chunyu, Lopez, Lorna M., Nolte, Ilja M., O'Connell, Jeffrey R., Tanaka, Toshiko, Trompet, Stella, Arnold, Alice, Bandinelli, Stefania, Beekman, Marian, Böhringer, Stefan, Brown, Suzanne J., Buckley, Brendan M., Camaschella, Clara, de Craen, Anton J. M., Davies, Gail, de Visser, Marieke C. H., Ford, Ian, Forsen, Tom, Frayling, Timothy M., Fugazzola, Laura, Gögele, Martin, Hattersley, Andrew T., Hermus, Ad R., Hofman, Albert, Houwing-Duistermaat, Jeanine J., Jensen, Richard A., Kajantie, Eero, Kloppenburg, Margreet, Lim, Ee M., Masciullo, Corrado, Mariotti, Stefano, Minelli, Cosetta, Mitchell, Braxton D., Nagaraja, Ramaiah, Netea-Maier, Romana T., Palotie, Aarno, Persani, Luca, Piras, Maria G., Psaty, Bruce M., Räikkönen, Katri, Richards, J. Brent, Rivadeneira, Fernando, Sala, Cinzia, Sabra, Mona M., Sattar, Naveed, Shields, Beverley M., Soranzo, Nicole, Starr, John M., Stott, David J., Sweep, Fred C. G. J., Usala, Gianluca, van der Klauw, Melanie M., van Heemst, Diana, van Mullem, Alies, H.Vermeulen, Sita, Visser, W. Edward, Walsh, John P., Westendorp, Rudi G. J., Widen, Elisabeth, Zhai, Guangju, Cucca, Francesco, Deary, Ian J., Eriksson, Johan G., Ferrucci, Luigi, Fox, Caroline S., Jukema, J. Wouter, Kiemeney, Lambertus A., Pramstaller, Peter P., Schlessinger, David, Shuldiner, Alan R., Slagboom, Eline P., Uitterlinden, André G., Vaidya, Bijay, Visser, Theo J., Wolffenbuttel, Bruce H. R., Meulenbelt, Ingrid, Rotter, Jerome I., Spector, Tim D., Hicks, Andrew A., Toniolo, Daniela, Sanna, Serena, Peeters, Robin P., Naitza, Silvia
    Publicado 2013
    “…Five of the reported loci (PDE8B, PDE10A, MAF/LOC440389, NETO1/FBXO15, and LPCAT2/CAPNS2) show strong gender-specific differences, which offer clues for the known sexual dimorphism in thyroid function and related pathologies. …”
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    A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function
  7. 10207
    por Lensink, Marc F., Velankar, Sameer, Kryshtafovych, Andriy, Huang, Shen‐You, Schneidman‐Duhovny, Dina, Sali, Andrej, Segura, Joan, Fernandez‐Fuentes, Narcis, Viswanath, Shruthi, Elber, Ron, Grudinin, Sergei, Popov, Petr, Neveu, Emilie, Lee, Hasup, Baek, Minkyung, Park, Sangwoo, Heo, Lim, Rie Lee, Gyu, Seok, Chaok, Qin, Sanbo, Zhou, Huan‐Xiang, Ritchie, David W., Maigret, Bernard, Devignes, Marie‐Dominique, Ghoorah, Anisah, Torchala, Mieczyslaw, Chaleil, Raphaël A.G., Bates, Paul A., Ben‐Zeev, Efrat, Eisenstein, Miriam, Negi, Surendra S., Weng, Zhiping, Vreven, Thom, Pierce, Brian G., Borrman, Tyler M., Yu, Jinchao, Ochsenbein, Françoise, Guerois, Raphaël, Vangone, Anna, Rodrigues, João P.G.L.M., van Zundert, Gydo, Nellen, Mehdi, Xue, Li, Karaca, Ezgi, Melquiond, Adrien S.J., Visscher, Koen, Kastritis, Panagiotis L., Bonvin, Alexandre M.J.J., Xu, Xianjin, Qiu, Liming, Yan, Chengfei, Li, Jilong, Ma, Zhiwei, Cheng, Jianlin, Zou, Xiaoqin, Shen, Yang, Peterson, Lenna X., Kim, Hyung‐Rae, Roy, Amit, Han, Xusi, Esquivel‐Rodriguez, Juan, Kihara, Daisuke, Yu, Xiaofeng, Bruce, Neil J., Fuller, Jonathan C., Wade, Rebecca C., Anishchenko, Ivan, Kundrotas, Petras J., Vakser, Ilya A., Imai, Kenichiro, Yamada, Kazunori, Oda, Toshiyuki, Nakamura, Tsukasa, Tomii, Kentaro, Pallara, Chiara, Romero‐Durana, Miguel, Jiménez‐García, Brian, Moal, Iain H., Férnandez‐Recio, Juan, Joung, Jong Young, Kim, Jong Yun, Joo, Keehyoung, Lee, Jooyoung, Kozakov, Dima, Vajda, Sandor, Mottarella, Scott, Hall, David R., Beglov, Dmitri, Mamonov, Artem, Xia, Bing, Bohnuud, Tanggis, Del Carpio, Carlos A., Ichiishi, Eichiro, Marze, Nicholas, Kuroda, Daisuke, Roy Burman, Shourya S., Gray, Jeffrey J., Chermak, Edrisse, Cavallo, Luigi, Oliva, Romina, Tovchigrechko, Andrey, Wodak, Shoshana J.
    Publicado 2016
    “…For those, a much poorer prediction performance was achieved, while nonetheless often providing helpful clues on the correct oligomeric state of the protein. …”
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    Prediction of homoprotein and heteroprotein complexes by protein docking and template‐based modeling: A CASP‐CAPRI experiment
  8. 10208
    “…This process provides epidemiological clues that facilitate a user’s understanding of an unfolding outbreak and facilitates informed decisions about mitigation actions. …”
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    Analytics for Investigation of Disease Outbreaks: Web-Based Analytics Facilitating Situational Awareness in Unfolding Disease Outbreaks
  9. 10209
    por Yun, Je-Yeon, Boedhoe, Premika S W, Vriend, Chris, Jahanshad, Neda, Abe, Yoshinari, Ameis, Stephanie H, Anticevic, Alan, Arnold, Paul D, Batistuzzo, Marcelo C, Benedetti, Francesco, Beucke, Jan C, Bollettini, Irene, Bose, Anushree, Brem, Silvia, Calvo, Anna, Cheng, Yuqi, Cho, Kang Ik K, Ciullo, Valentina, Dallaspezia, Sara, Denys, Damiaan, Feusner, Jamie D, Fouche, Jean-Paul, Giménez, Mònica, Gruner, Patricia, Hibar, Derrek P, Hoexter, Marcelo Q, Hu, Hao, Huyser, Chaim, Ikari, Keisuke, Kathmann, Norbert, Kaufmann, Christian, Koch, Kathrin, Lazaro, Luisa, Lochner, Christine, Marques, Paulo, Marsh, Rachel, Martínez-Zalacaín, Ignacio, Mataix-Cols, David, Menchón, José M, Minuzzi, Luciano, Morgado, Pedro, Moreira, Pedro, Nakamae, Takashi, Nakao, Tomohiro, Narayanaswamy, Janardhanan C, Nurmi, Erika L, O’Neill, Joseph, Piacentini, John, Piras, Fabrizio, Piras, Federica, Reddy, Y C Janardhan, Sato, Joao R, Simpson, H Blair, Soreni, Noam, Soriano-Mas, Carles, Spalletta, Gianfranco, Stevens, Michael C, Szeszko, Philip R, Tolin, David F, Venkatasubramanian, Ganesan, Walitza, Susanne, Wang, Zhen, van Wingen, Guido A, Xu, Jian, Xu, Xiufeng, Zhao, Qing, Thompson, Paul M, Stein, Dan J, van den Heuvel, Odile A, Kwon, Jun Soo
    Publicado 2020
    “…Large-scale investigation of structural covariance networks in obsessive-compulsive disorder (OCD) may provide clues to the pathophysiology of this neurodevelopmental disorder. …”
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    Brain structural covariance networks in obsessive-compulsive disorder: a graph analysis from the ENIGMA Consortium
  10. 10210
    “…The results showed that m(7)GDisAI identified disease-associated m(7)G sites and their host genes are consistently related to the pathogenesis of ovarian cancer, which may provide some clues for pathogenesis of diseases. CONCLUSION: The m(7)GDisAI web server can be accessed at http://180.208.58.66/m7GDisAI/, which provides a user-friendly interface to query disease associated m(7)G. …”
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    m(7)GDisAI: N7-methylguanosine (m(7)G) sites and diseases associations inference based on heterogeneous network
  11. 10211
    “…PPG signals from fingertip videos, captured under various light sources, can provide critical physiological clues. The features of PPG signals captured under 1070 nm and 850 nm NIR LED are considered to be the best signal combinations following a dual-wavelength theoretical foundation. …”
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    Noninvasive Hemoglobin Level Prediction in a Mobile Phone Environment: State of the Art Review and Recommendations
  12. 10212
    “…IMPORTANCE: Understanding of SARS-CoV-2 variants that alter disease outcomes are important for clinical risk stratification and may provide important clues to the complex virus-host relationship. OBJECTIVE: To examine the association of identified SARS-CoV-2 variants, virus clades, and clade groups with disease severity and patient outcomes. …”
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    Genomic Epidemiology of SARS-CoV-2 Infection During the Initial Pandemic Wave and Association With Disease Severity
  13. 10213
    “…CONCLUSIONS: This review provides clues about the severity of the indirect influence of COVID-19 lockdown implementation; however, the criteria that lead to unexpected changes in LBW, PTB, and stillbirth remains unclear. …”
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    The impact of COVID-19 first wave national lockdowns on perinatal outcomes: a rapid review and meta-analysis
  14. 10214
    “…This study explores the molecular mechanisms of Chronic chagasic cardiomyopathy and provides important clues for finding new therapeutic targets. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12920-021-01134-3.…”
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    Comprehensive analysis of miRNA–mRNA regulatory network and potential drugs in chronic chagasic cardiomyopathy across human and mouse
  15. 10215
    “…The objectives of APHYPAP are twofold: a clinical aim with the evaluation of the efficacy of two drugs in the treatment of a persistent AP for MPN patients and a biological aim to find clues to elucidate AP pathophysiology. METHODS/DESIGN: A multicentric, double-blind, double-placebo, randomized study will include 80 patients with MPN (PV or ET or PMF) treated since at least 6 months for their hemopathy but suffering from a persistent AP (VAS intensity ≥6/10). …”
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    Rationale and design of the multicentric, double-blind, double-placebo, randomized trial APrepitant versus HYdroxyzine in association with cytoreductive treatments for patients with myeloproliferative neoplasia suffering from Persistent Aquagenic Pruritus. Trial acronym: APHYPAP
  16. 10216
    “…Thus, in long run, this study may provide novel clues to therapeutically target RBD-ACE2 interface for pan-sarbecovirus infections. …”
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    Mutational landscape and in silico structure models of SARS-CoV-2 spike receptor binding domain reveal key molecular determinants for virus-host interaction
  17. 10217
    por Zhao, Hui, He, Yue, Fan, Bei, Wang, Yan, Wu, Yu-Mei
    Publicado 2022
    “…Although it is well known that the tests of human papillomavirus E6/E7 RNA location in infected cervical cells and cell internal malignancy molecular will provide clues for gynecologists to evaluate disease progression, there are technique difficulties to preserve RNAs in cervical scraped cells for in situ hybridization. …”
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    Human papillomavirus E6E7 mRNA and TERC lncRNA in situ detection in cervical scraped cells and cervical disease progression assessment
  18. 10218
    “…The associations of the three genes with HCC microenvironment and anti-cancer drug sensitivities would provide new clues for HCC immunotherapy and chemotherapy. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12935-022-02820-7.…”
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    CD5L-associated gene analyses highlight the dysregulations, prognostic effects, immune associations, and drug-sensitivity predicative potentials of LCAT and CDC20 in hepatocellular carcinoma
  19. 10219
    “…Our findings provide new clues to the epigenetic modification underlying hypertension pathogenesis. …”
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    Epigenome-wide association study in Chinese monozygotic twins identifies DNA methylation loci associated with blood pressure
  20. 10220
    “…This study aimed to analyze the epidemiological characteristics of cleft lip and/or palate (CL/P) and CL/P-related perinatal deaths, provide some information for intervention programs to reduce the incidence of CL/P and provide clues for future researchers. Data were obtained from the Birth Defects Surveillance System in Hunan Province, China, 2016–2020. …”
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    Incidence of cleft lip and palate, and epidemiology of perinatal deaths related to cleft lip and palate in Hunan Province, China, 2016–2020
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