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  1. 10681
    “…Our results provide a clue for blocking compensatory proteasome synthesis to improve cancer therapies targeting proteasomes. …”
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    The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction
  2. 10682
    “…Angiogenesis is a clue process for tissue development and function, both in normal and pathological conditions. …”
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    The era of anti-vascular endothelial growth factor (VEGF) drugs in ophthalmology, VEGF and anti-VEGF therapy
  3. 10683
    “…We anticipate that such ultrafast microscopic fluxional processes in lithium-solvent complexes could provide an important clue to understanding macroscopic mobility of lithium cation in lithium-ion battery on a molecular level.…”
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    Ultrafast fluxional exchange dynamics in electrolyte solvation sheath of lithium ion battery
  4. 10684
    “…Persistent vomiting and paucity of air on the plain abdominal films provided a clue to the diagnosis. A CT scan of the abdomen with contrast revealed a uniformly thin walled fluid attenuation mass in the epigastric region which did not opacify with contrast. …”
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    Gastric Duplication: A Rare Cause of Recurrent Vomiting
  5. 10685
    “…The cutaneous manifestations of cryptococcosis can be the first clue for a disseminated disease, which makes early recognition crucial and life-saving.…”
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    Progressive cutaneous Cryptococcosis complicated with meningitis in a myasthenia gravis patient on long-term immunosuppressive therapy – a case report
  6. 10686
    “…Although the structure provided little clue to its function, based on the structure of NSP7α, we predicted and further identified some key amino acids on NSP7α for the interaction of NSP7α with NSP9, the RNA dependent RNA polymerase of PRRSV. …”
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    Structural Analysis of Porcine Reproductive and Respiratory Syndrome Virus Non-structural Protein 7α (NSP7α) and Identification of Its Interaction with NSP9
  7. 10687
    “…Thus, the strategy of this virus is indivisibly linked with its pathogenesis, providing a clue for prevention and treatment of HTLV-1-induced diseases. …”
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    Human T-cell leukaemia virus type 1: parasitism and pathogenesis
  8. 10688
    por Argento, Angelo
    Publicado 2012
    “…This case illustrates the significance of recognizing hypercalcemia as a potential clue in detecting underlying colon cancer involving overproduction of PTH-rp. …”
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    Hypercalcemia as a Presenting Clinical Manifestation of Adenocarcinoma of the Colon
  9. 10689
    “…CONCLUSIONS AND IMPORTANCE: Segmental arteriolar staining that migrates towards the periphery may be a clue to the etiology of this disease process.…”
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    Migration of segmental arteriolar fluorescein staining peripherally in eye with idiopathic recurrent branch retinal arterial occlusion
  10. 10690
    “…The combination of a butyrate ester and a bare phenol-OH group in the honokiol structure seemed to play a significant role in the antiproliferative activity identifying an interesting pharmacological clue against hepatocellular carcinoma.…”
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    Synthesis of magnolol and honokiol derivatives and their effect against hepatocarcinoma cells
  11. 10691
    “…These observations provide the first clue that the Ca‐binding protein, sorcin, may play an important role in the development of the multidrug resistance phenomenon, although the relationship between sorcin and P‐glycoprotein is still unknown.…”
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    Immunocytochemical Identification and Localization of the Mr 22,000 Calcium‐binding Protein (Sorcin) in an Adriamycin‐resistant Myelogenous Leukemia Cell Line
  12. 10692
    “…It seems that ESR includes not only anemia and infection components but also provides a clue to the degree of bone metastasis or the degree of prostate cancer progression.…”
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    The Significance of Erythrocyte Sedimentation Rate as a Prognostic Factor for Patients with Prostate Cancer: Gunma Urological Oncology Study Group Investigation
  13. 10693
    “…Existence of pseudocysts even in feline trichomonads is noteworthy as they could represent a form of protozoan resistance due to unfavorable conditions whose detection in refrigerated feces can be a useful clue for clinicians.…”
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    Coinfection with Tritrichomonas foetus and Giardia duodenalis in Two Cats with Chronic Diarrhea
  14. 10694
    “…However, the neural mechanisms of this rejection–aggression link remain unclear. A potential clue may be that rejected people often recruit the ventrolateral prefrontal cortex’s (VLPFC) self-regulatory processes to manage the pain of rejection. …”
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    Neural mechanisms of the rejection–aggression link
  15. 10695
    “…Cervical smear findings can be the only clue for the diagnosis of fallopian tube carcinoma.…”
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    Primary fallopian tube carcinoma diagnosed preoperatively by cervical smear
  16. 10696
    “…We propose that the “pulling sensation” described may be a clue to the diagnosis in some patients in which the urachal remnant is attached to the bladder and that the sensation was due to the mechanical connection between the bladder and the umbilicus. …”
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    An Adult with a Remnant Urachus Anomaly Diagnosed in the Emergency Department
  17. 10697
    “…Unexplained chest pain following PPM insertion might be the only clue for such complication, although it might not always be present.…”
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    Chest pain following permanent pacemaker insertion… a case of pneumopericardium due to atrial lead perforation
  18. 10698
    “…Therefore, SlCOMT1 was closely associated with melatonin biosynthesis confers the significant salt tolerance, providing a clue to cope with the growing global problem of salination in agricultural production.…”
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    Overexpression of the Melatonin Synthesis-Related Gene SlCOMT1 Improves the Resistance of Tomato to Salt Stress
  19. 10699
    “…Introducing suitable nanomaterials in polymer-based nanocomposites can be an answer to this clue. In this work, an industry-compliant cable-grade P-PVC formulation was added with nanostructured materials belonging to the family of Polyhedral Oligomeric Silsesquioxane (POSS). …”
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    The Use of POSS-Based Nanoadditives for Cable-Grade PVC: Effects on Its Thermal Stability
  20. 10700
    “…Though screening PHPT patients for SC might not be justified/warranted given the benign course of the latter, patients with SC need to be assessed for PHPT, as the former may be the first clue to an underlying treatable systemic disease. …”
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    A rare ophthalmic condition associated with primary hyperparathyroidism (PHPT): sclerochoroidal calcification (SC)
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