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  1. 10741
    por Liu, B, Wen, X, Cheng, Y
    Publicado 2013
    “…To address these problems, we focus on summarizing the dynamic oncogenic and tumor suppressive roles of autophagy and their relevant small-molecule drugs, which would provide a new clue to elucidate the oncosuppressive (survival or death) autophagic network as a potential therapeutic target.…”
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    Survival or death: disequilibrating the oncogenic and tumor suppressive autophagy in cancer
  2. 10742
    “…The absence of estrogens is a clue factor in the onset of cardiovascular disease during the menopausal period, which is characterized by lipid profile variations and predominant abdominal fat accumulation. …”
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    Estrogen Deficiency and the Origin of Obesity during Menopause
  3. 10743
    “…Therefore, we suggest that abnormal hernial sacs may be the first clue to an underlying cancer, and should be sent for histological examination. …”
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    Incidental finding of a malignant tumour in an inguinal hernia sac
  4. 10744
    “…This paper optimises projected land-use structure in 2020 with the goal of increasing terrestrial ecosystem carbon storage and simulates its spatial distribution using the CLUE-S model. We found the following: The total carbon densities of different land use types were woodland > water area > cultivated land > built-up land > grassland > shallows. …”
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    Spatial Simulation of Land Use based on Terrestrial Ecosystem Carbon Storage in Coastal Jiangsu, China
  5. 10745
    “…Our novel findings may provide an important clue and approach to managing formidable repetitive double J stent calculi formation in the clinical trial.…”
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    Successful Management of Repetitive Urinary Obstruction and Anuria Caused by Double J Stent Calculi Formation after Renal Transplantation
  6. 10746
    “…RESULTS: Beside the anamnestic clue, presentation of AN-like plaques in the “neglected nipples” is limited to the breasts, in the absence of involvement of other flexural sites classically affected by AN. …”
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    “Neglected nipples”: acanthosis nigricans-like plaques caused by avoidance of nipple cleansing
  7. 10747
    “…Lactate levels in emergency give the earliest clue to cardiovascular compromise and poor tissue perfusion. …”
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    Bedside ABG, electrolytes, lactate and procalcitonin in emergency pediatrics
  8. 10748
    “…CONCLUSIONS: Pigmented infiltrates can be an important diagnostic clue, but a microscopic evaluation and culture are required to obtain an accurate diagnosis of Fonsecaea keratitis. …”
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    Corneal Chromoblastomycosis Caused by Fonsecaea pedrosoi
  9. 10749
    “…We describe an unusual presentation of primary antiphospholipid syndrome mimicking vasculitis for which the only diagnostic clue on initial presentation was antiphospholipid syndrome nephropathy. …”
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    Primary antiphospholipid syndrome presenting as antiphospholipid syndrome nephropathy: a case report
  10. 10750
    “…Taken together, these results suggest that TAW induces paraptosis like cell death and protective autophagy in HeLa cells, which would provide a new clue for exploiting TAW as a promising agent for the treatment of cervical cancer.…”
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    8-p-Hdroxybenzoyl Tovarol Induces Paraptosis Like Cell Death and Protective Autophagy in Human Cervical Cancer HeLa Cells
  11. 10751
    por Kumar, Bijoy Mohan, Munakomi, Sunil
    Publicado 2015
    “…Bilateral EDB wasting thereby provides a clinical clue to the underlying lumbar canal stenosis and can help in making correct therapeutic decisions.…”
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    Case Report: A case report highlighting bilateral EDB wasting as a clinical marker for lumbar canal stenosis
  12. 10752
    “…Thus, these findings provide a clue to understand, at the molecular level, the evolution of alphaviruses and their host range.…”
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    A Viral mRNA Motif at the 3′-Untranslated Region that Confers Translatability in a Cell-Specific Manner. Implications for Virus Evolution
  13. 10753
    “…These findings thus provide a new clue of antimicrobial peptides as a potential novel therapy for leukemia.…”
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    PFR peptide, one of the antimicrobial peptides identified from the derivatives of lactoferrin, induces necrosis in leukemia cells
  14. 10754
    “…In the process of seeking a general strategy to design high-affinity binders, we found a clue from the βPIX (p21-activated kinase interacting exchange factor)−Shank PDZ interaction in synaptic assembly: three PDZ-binding sites are clustered by a parallel coiled-coil trimer but bind to Shank PDZ protein with 1:1 stoichiometry (1 trimer/1 PDZ). …”
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    Affinity Enhancement by Ligand Clustering Effect Inspired by Peptide Dendrimers−Shank PDZ Proteins Interactions
  15. 10755
    “…The hyperdense basilar artery sign is one of the earliest signs on non-contrast CT imaging and may be the only clue to guide further management in a patient with basilar artery occlusion.…”
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    The hyperdense basilar artery sign: a case of locked-in syndrome
  16. 10756
    “…These findings provide us a clue to elucidate a unique DNA repair system in Archaea.…”
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    PCNA is involved in the EndoQ-mediated DNA repair process in Thermococcales
  17. 10757
    “…The results suggest that screening reference gene during latex flow should be an efficient and effective clue for selection of reference genes in qRT-PCR.…”
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    Evaluation of Reference Genes for Quantitative Real-Time PCR Analysis of the Gene Expression in Laticifers on the Basis of Latex Flow in Rubber Tree (Hevea brasiliensis Muell. Arg.)
  18. 10758
    por Wu, Yun, Zheng, Yufei, Tang, Hua
    Publicado 2016
    “…Thus, correctly identifying the types of ion channel-targeted conotoxins will provide important clue to understand their function and find potential drugs. …”
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    Identifying the Types of Ion Channel-Targeted Conotoxins by Incorporating New Properties of Residues into Pseudo Amino Acid Composition
  19. 10759
    “…Here, we present a novel bariatric procedure to clue out a female child 13 years old presented with Legg–Calvé–Perthes disease-associated morbid obesity. …”
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    Bariatric Bypass Surgery to Resolve Complicated Childhood Morbid Obesity: Case Report Study
  20. 10760
    “…The numbers of membrane proteins in the current genomes of various organisms provide an important clue about how the protein world has evolved from the aspect of membrane proteins. …”
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    Ratio of membrane proteins in total proteomes of prokaryota
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