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  1. 10881
    “…Travel history may provide a clue to the most probable species. This case demonstrates a case of C gattii meningitis with a multiplicity of complications. …”
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    A Rare Case of Cryptococcus gattii Meningitis in Advanced HIV Disease, Sagittal Thrombosis, and Immune Reconstitution Syndrome, Resolved With Isavuconazonium
  2. 10882
    “…The circadian day–night is the rhythmic clue to organisms for their synchronized body functions. …”
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    Artificial Light at Night (ALAN): A Potential Anthropogenic Component for the COVID-19 and HCoVs Outbreak
  3. 10883
    “…However, further study investigating the key bacteria for cervical cancer is still needed, which can be a clue for the diagnosis or treatment of cervical cancer.…”
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    Revealing the Disturbed Vaginal Micobiota Caused by Cervical Cancer Using High-Throughput Sequencing Technology
  4. 10884
    “…Furthermore, reducing the thickness of platelet LDH crystals to nanometer or even molecular scale via cleavage or delamination provides an important clue to enhance the activity. In this review, recent progresses on rational design of LDH nanosheets are reviewed, including direct synthesis via traditional coprecipitation, homogeneous precipitation, and newly developed topochemical oxidation as well as chemical exfoliation of parent LDH crystals. …”
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    2D Layered Double Hydroxide Nanosheets and Their Derivatives Toward Efficient Oxygen Evolution Reaction
  5. 10885
    “…This imaging characteristic can be a clue to look for underlying hormone deficiency, especially in primary hypothyroidism. …”
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    Dome-Shaped Pituitary Enlargement in Primary Hypothyroidism: Avoiding Neurosurgical Interventions
  6. 10886
    “…Taken together, our data highlight a molecular mechanism for the regulation of Th17 differentiation and functions, which may represent a new intervening clue for Th17-related diseases.…”
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    SOX-5 activates a novel RORγt enhancer to facilitate experimental autoimmune encephalomyelitis by promoting Th17 cell differentiation
  7. 10887
    “…Overall, our analysis provided a better understanding of the heterogeneity of differential models for beige adipocytes activation and a possible clue for optimizing β3-AR agonists in the future.…”
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    Comparative Transcriptome Profiling of Cold Exposure and β3-AR Agonist CL316,243-Induced Browning of White Fat
  8. 10888
    por Husen, Peter, Solov’yov, Ilia A.
    Publicado 2021
    “…Furthermore, simulations of the product state reveal that superoxide formed at the Q(o)-site exclusively leaves the [Formula: see text] complex at the positive side of the membrane and escapes into the intermembrane space of mitochondria, providing a critical clue in further studies of the harmful effects of mitochondrial superoxide production.…”
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    Modeling the Energy Landscape of Side Reactions in the Cytochrome bc(1) Complex
  9. 10889
    “…The differential diagnosis is quite broad; it can be an incidental finding in otherwise healthy adults or the first clue to a lethal pathology. CASE PRESENTATION: This case highlights a patient who presented with symptomatic sinus bradycardia, which resulted in syncope requiring admission for permanent pacemaker implantation and later found to have an underlying adrenal insufficiency (AI). …”
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    A case of isolated sinus bradycardia as an unusual presentation of adrenal insufficiency
  10. 10890
    “…All data presented in this study have been deposited to the ProteomeXchange Consortium with identifiers PXD017458 (P100) and PXD017459 (GCP) and can be queried at https://clue.io/proteomics.…”
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    Proteomic profiling dataset of chemical perturbations in multiple biological backgrounds
  11. 10891
    “…This natural selective trait of Synechococcus and heterotrophic bacteria toward mutualism under long-term coexistence provides a novel clue for understanding the ubiquity and competitive advantage of Synechococcus in global oceans.…”
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    Long-Term Survival of Synechococcus and Heterotrophic Bacteria without External Nutrient Supply after Changes in Their Relationship from Antagonism to Mutualism
  12. 10892
    “…However, since MRI is increasingly used in daily clinical practice, the chance detection of such DWI abnormalities would have important implications in terms of providing a clue to examine a highly specific early diagnostic marker to be developed in the future for CJD. …”
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    Case Report: Extremely Early Detection of Preclinical Magnetic Resonance Imaging Abnormality in Creutzfeldt–Jakob Disease With the V180I Mutation
  13. 10893
    por Laborada, Jennifer, Cohen, Philip R
    Publicado 2021
    “…Yellow to brown discoloration of the thumbnails, fingernails, or both (such as nicotine sign and/or harlequin nails) may be an accompanying clinical stigma to the smoker’s mustache and a clue to the diagnosis. Management options include smoking cessation or hair removal of the discolored hair, or both; however, patients usually elect to continue smoking, maintain their facial hair, and continue to display their distinctive yellow smoker’s mustache.…”
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    Smoker’s Mustache Revisited: Upper Lip Hair Yellow Discoloration Associated With Tobacco
  14. 10894
    “…The findings provide a useful clue for developing new chemotherapeutic strategies against TNBCs.…”
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    Paclitaxel-induced stress granules increase LINE-1 mRNA stability to promote drug resistance in breast cancer cells
  15. 10895
    “…We suggest that the combination of Cogan ocular motor apraxia, hypoplastic nails of fifth toes, and developmental delay give the important diagnostic clue for a variant in the SOX11 gene (OMIM 615866, MR 27).…”
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    Maternal transmission of a mild Coffin–Siris syndrome phenotype caused by a SOX11 missense variant
  16. 10896
    “…This response was greatly muted in monocytes from healthy children, perhaps a clue to the age dependency of COVID-19. These results suggest that the inflammatory malfunction in COVID-19 is rooted in the earliest perturbations that SARS-CoV-2 induces in epithelia.…”
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    A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV-2 at the immune–epithelial interface
  17. 10897
    “…By comparing the BALF aqueous expression of cytokines/chemokines with that in sorted T cells, our data give a preliminary clue capable of finishing out the possible cell source of the proinflammatory cytokines/chemokines from the BALF mixture. …”
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    Exhausted and Apoptotic BALF T Cells in Proinflammatory Airway Milieu at Acute Phase of Severe Mycoplasma Pneumoniae Pneumonia in Children
  18. 10898
    “…Collectively, these inspiring findings would provide a clue on developing more novel avenues for pharmacological modulations of ncRNAs with small-molecule drugs for future cancer therapeutics.…”
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    Designing strategies of small-molecule compounds for modulating non-coding RNAs in cancer therapy
  19. 10899
    “…Ultimately, these findings provide a critical clue that the characteristics of the photoinduced normal state show a solid resemblance to those under magnetic fields in equilibrium conditions.…”
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    Characterization of photoinduced normal state through charge density wave in superconducting YBa(2)Cu(3)O(6.67)
  20. 10900
    “…Together, our study provides a new clue for deciphering the interplay mechanism between R-loops and HMs to control cell reprogramming.…”
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    The Cumulative Formation of R-loop Interacts with Histone Modifications to Shape Cell Reprogramming
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