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  1. 11041
    “…A characteristic skin rash is a key diagnostic clue pointing to purpura fulminans, and should lead to prompt institution of therapy, as waiting for a skin biopsy result can delay the diagnosis and result in significant morbidity and mortality. …”
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    Purpura Fulminans: a Rare but Fierce Presentation of Pneumococcal Sepsis
  2. 11042
    “…Investigation of genes expressed with regular monotonic patterns (known as Monotonically Expressed Genes (MEGs)) and of their master regulators can provide important clue for the understanding of the molecular mechanisms underlying the AAT disease. …”
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    Computational Identification of Master Regulators Influencing Trypanotolerance in Cattle
  3. 11043
    “…The collected fusion gene data were compiled for each cancer and analyzed to identify their functions related to cancer and associated pathways using Ingenuity Pathway Analysis (IPA) and ClueGO software programs. Similarities in associated pathways across different cancers were also analyzed using IPA to identify commonly affected genes and pathways. …”
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    A compiled dataset of molecular pathways associated with fusion genes identified in pediatric cancers
  4. 11044
    “…These findings may provide a clue for developing a strategy to reduce the impact of grazer contamination in commercial-scale microalgal cultivation.…”
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    Phosphite Reduces the Predation Impact of Poterioochromonas malhamensis on Cyanobacterial Culture
  5. 11045
    “…Accumulating knowledge to control stress-induced damage may provide a clue for extending healthspan and treating aging-related diseases. …”
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    Online Artículo Texto
    The KEAP1-NRF2 System in Healthy Aging and Longevity
  6. 11046
    “…Although initially missed, a careful re-evaluation of chest X-ray provided the diagnostic clue of a mediastinal mass effect on cerebral venous drainage. …”
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    Online Artículo Texto
    A thymic cyst presenting as first episode 'status epilepticus'
  7. 11047
    “…Gaze estimation, which is a method to determine where a person is looking at given the person’s full face, is a valuable clue for understanding human intention. Similarly to other domains of computer vision, deep learning (DL) methods have gained recognition in the gaze estimation domain. …”
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    Gaze Estimation Approach Using Deep Differential Residual Network
  8. 11048
    “…Understanding this mechanism might offer a better clue for an efficient treatment in SLE patients. …”
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    Online Artículo Texto
    Interferon in systemic lupus erythematosus—A halfway between monogenic autoinflammatory and autoimmune disease
  9. 11049
    por Abdelhamid, Ahmed T.
    Publicado 2022
    “…Physical examination including auscultation of bowel sounds in the chest offers a diagnostic clue but the mainstay of diagnosis by chest imaging including chest roentgenogram and CT scan of the thorax and abdomen.…”
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    Non-traumatic left-sided diaphragmatic hernia causing volvulus in an adult
  10. 11050
    “…This observation gave a clue of the involvement of gut-lung axis in this disease development and progression. …”
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    Online Artículo Texto
    Decoding the bidirectional relationship between gut microbiota and COVID-19
  11. 11051
    por Tsai, Chia-Che, Chiang, Yi-Pin
    Publicado 2023
    “…The specific finding of a “partial eclipse sign” could be a useful additional clue leading to the correct diagnosis of the nursemaid’s elbow and may help avoid the unnecessary reduction in patients who do not have a “partial eclipse sign”. …”
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    The Usefulness of Dynamic Ultrasonography in Nursemaid’s Elbow: A Prospective Case Series of 13 Patients Reconsideration of the Pathophysiology of Nursemaid’s Elbow
  12. 11052
    “…CONCLUSIONS: The handgrip strength in Type 1 DM children is affected by the degree of the glycemic control and it might give a clue of early musculoskeletal functional derangement by the effect of chronic hyperglycemia in these affected children.…”
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    Correlation Between Hand Grip Strength and Glycemic Control Among Saudi Children with Chronic Type 1 Diabetes Mellitus (T1DM)
  13. 11053
    “…BACKGROUND: New-onset anisocoria is an important clinical clue to life-threatening intracranial injury. Anisocoria alone without impairment of extraocular muscles is a rare presentation of moderate traumatic brain injury (TBI). …”
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    Anisocoria without extraocular muscle impairment due to moderate traumatic brain injury with midbrain contusion: a case report
  14. 11054
    “…Our findings suggest that mesothelial cell profibrotic property may be an important player in IPF pathogenesis and may be a clue in the irreversibility of fibrosis in IPF.…”
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    Properties of Pleural Mesothelial Cells in Idiopathic Pulmonary Fibrosis and Cryptogenic Organizing Pneumonia
  15. 11055
    “…Colchicine administration, at first empirically for upcoming pericarditis, at the end was a significant clue for the diagnosis. Positive molecular testing for mutations in the familial Mediterranean fever (MEFV) gene contributed to the diagnosis of FMF, which was based on the Tel-Hashomer clinical criteria. …”
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    Familial Mediterranean Fever in a 28-Year-Old Male Presented as a Painless Massive Pleural Effusion
  16. 11056
    “…Borage, during the non-flowering seasons, can be easily confused with foxglove (Digitalis spp.), and this was the main clue to suspect poisoning. Both patients were given DigiFab®, a sheep antibody fragment with high affinity for digoxin. …”
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    In the kingdom of “tortelli” (ravioli-like pasta) plant poisoning is still a threat. A case report of near-fatal poisoning from Digitalis Purpurea accidentally confused with Borago Officinalis
  17. 11057
    “…This study may offer an insightful clue regarding how PE is related to the abnormal regulation of the rewarding aspect of sexual behavior.…”
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    Altered reward processing in patients with lifelong premature ejaculation
  18. 11058
    “…Identification of CIRP may provide a clue to the regulatory mechanisms of cold responses in mammalian cells.…”
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    A Glycine-rich RNA-binding Protein Mediating Cold-inducible Suppression of Mammalian Cell Growth
  19. 11059
    “…The mechanism by which T cell receptor specificity determines the outcome of the CD4/CD8 lineage decision in the thymus is not known. An important clue is the fact that major histocompatibility complex (MHC)-I–signaled thymocytes paradoxically appear as CD4(+)8(lo) transitional cells during their differentiation into CD8(+) T cells. …”
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    Unraveling a Revealing Paradox: Why Major Histocompatibility Complex I–signaled Thymocytes “Paradoxically” Appear as CD4(+)8(lo) Transitional Cells During Positive Selection of CD8(+) T Cells
  20. 11060
    “…How XIST RNA strictly localizes across the inactive X chromosome is unknown; however, prophase release of human XIST RNA provides a clue. Tests of inhibitors that mimic mitotic chromatin modifications implicated an indirect role of PP1 (protein phosphatase 1), potentially via its interphase repression of Aurora B kinase (AURKB), which phosphorylates H3 and chromosomal proteins at prophase. …”
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    AURKB-mediated effects on chromatin regulate binding versus release of XIST RNA to the inactive chromosome
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