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  1. 11721
    “…The identification of conserved epitopes within specific HA subtypes gives an important clue for developing new vaccines and diagnostics. …”
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    Insight into Highly Conserved H1 Subtype-Specific Epitopes in Influenza Virus Hemagglutinin
  2. 11722
    “…Taken together, our results highlighted the dysregulation of developmental genes, thus suggesting a potential alteration of networks involved in the formation of the female reproductive tract and providing a useful clue for understanding the pathophysiology of MRKHS.…”
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    Gene Expression Profile of Patients with Mayer-Rokitansky-Küster-Hauser Syndrome: New Insights into the Potential Role of Developmental Pathways
  3. 11723
    “…The finding has provided further clue of association between HPV16 and breast cancer.…”
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    Detection and Analysis of Human Papillomavirus (HPV) DNA in Breast Cancer Patients by an Effective Method of HPV Capture
  4. 11724
    “…This work provides an insight into understanding the protein regulation mechanism of cassava polyploid genotype, and gives a clue to improve cassava polyploidy breeding in increasing photosynthesis and resistance efficiencies.…”
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    Comparison of Leaf Proteomes of Cassava (Manihot esculenta Crantz) Cultivar NZ199 Diploid and Autotetraploid Genotypes
  5. 11725
    “…However, the geographical variations in CHD prevalence would be highly valuable in providing a clue on the role of the environment in CHD etiology. …”
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    Spatial patterns of the congenital heart disease prevalence among 0- to 14-year-old children in Sichuan Basin, P. R China, from 2004 to 2009
  6. 11726
    “…Whereas the conventional morphology-based classification provides a clue for tumor growth and prognosis, the new classification by genetic alterations offers a basis for targeted therapy. …”
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    Comparison of Melanoma Subtypes among Korean Patients by Morphologic Features and Ultraviolet Exposure
  7. 11727
    “…Presence of prodromal pain, thickened cortex with cortical beaking may be an early clue for predicting the atypical fractures. High risk patients need periodical skeletal survey and a close follow up for early detection of cases.…”
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    Predictors of atypical femoral fractures during long term bisphosphonate therapy: A case series & review of literature
  8. 11728
    “…These proteins were further analyzed with ClueGO, a Cytoscape plugin, which provided gene ontology and the biological interaction processes of identified proteins. …”
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    Analysis of zinc oxide nanoparticles binding proteins in rat blood and brain homogenate
  9. 11729
    “…Several studies reported the ability of activated platelets to internalize bacteria such as Staphylococcus aureus or Porphyromonas gingivalis, though there is no clue on what happens thereafter. Are they sheltered from the immune system in the cytoplasm of platelets or are they lysed? …”
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    Platelets and Infections – Complex Interactions with Bacteria
  10. 11730
    “…CONCLUSIONS: Platelet count in nonalcoholic fatty liver disease can serve as a clue to the severity of disease, but it cannot be considered as a sole test to follow up patients.…”
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    Association Between Platelet Count as a Noninvasive Marker and Ultrasonographic Grading in Patients With Nonalcoholic Fatty Liver Disease
  11. 11731
    “…CONCLUSIONS: Elevation of serum AFP may be a clue leading to the diagnosis of pancreatic hepatoid carcinoma. …”
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    Hepatoid carcinoma of the pancreas
  12. 11732
    “…Histoplasma antigen was present in urine and/or serum in all but 3 of the patients and provided the first clue to the diagnosis of histoplasmosis for several patients. …”
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    Histoplasma capsulatum Endocarditis: Multicenter Case Series with Review of Current Diagnostic Techniques and Treatment
  13. 11733
    “…Ovarian endometriosis is a recognized risk for infertility and epithelial ovarian cancer, presumably due to iron overload resulting from repeated hemorrhage. To find a clue for early detection and prevention of ovarian endometriosis-associated cancer, it is mandatory to evaluate catalytic (labile) ferrous iron (catalytic Fe(II)) and to study iron manipulation in ovarian endometriotic lesions. …”
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    Ovarian endometriosis-associated stromal cells reveal persistently high affinity for iron
  14. 11734
    “…The finding of higher Marin County risk linked to a CYP11B2 aldosterone synthase SNP associated with essential hypertension offers a new genetic clue to sporadic breast cancer predisposition.…”
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    A steroid metabolizing gene variant in a polyfactorial model improves risk prediction in a high incidence breast cancer population
  15. 11735
    “…We will discuss whether nature offers a clue to assist the generation of a nephro-vascular unit that can attain functionality even prior to receiving external blood supply from a host. …”
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    Assembling Kidney Tissues from Cells: The Long Road from Organoids to Organs
  16. 11736
    por Michalski, Kevin, Kawate, Toshimitsu
    Publicado 2016
    “…However, it remains unclear how Panx1 senses and integrates such diverse stimuli to form an open channel. To provide a clue on the mechanism underlying Panx1 channel gating, we investigated the action mechanism of carbenoxolone (CBX), the most commonly used small molecule for attenuating Panx1 function triggered by a wide range of stimuli. …”
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    Carbenoxolone inhibits Pannexin1 channels through interactions in the first extracellular loop
  17. 11737
    “…Highly accumulated FAT10 is observed in various cancers with pro-inflammatory environment, therefore, our finding which uncovered the suppressive effect of the accumulated FAT10 during virus-mediated inflammatory response may also provide molecular clue to understand the carcinogenesis related with infection and inflammation.…”
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    Ubiquitin-like modifier FAT10 attenuates RIG-I mediated antiviral signaling by segregating activated RIG-I from its signaling platform
  18. 11738
    por Yamauchi, Yukina, Izawa, Shingo
    Publicado 2016
    “…Thus, our findings provide an important clue about yeast response to severe ethanol stress and suggest that the BTN2 promoter can be used to improve the efficiency of ethanol production and stress tolerance of yeast cells by modifying gene expression in the presence of high ethanol concentration.…”
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    Prioritized Expression of BTN2 of Saccharomyces cerevisiae under Pronounced Translation Repression Induced by Severe Ethanol Stress
  19. 11739
    “…Altered linkage patterns of intrinsic homotopic connectivity and impaired cognitive flexibility was first investigated in LOD, and it would provide a novel clue for revealing the neural substrates underlying cognitive impairment in LOD.…”
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    Disrupted Interhemispheric Synchrony in Default Mode Network Underlying the Impairment of Cognitive Flexibility in Late-Onset Depression
  20. 11740
    “…CONCLUSION: The results suggest that the endophytic fungus T. gamsii YIM PH30019 may have a good potential as a biological control agent against notoginseng phytodiseases and can provide a clue to further illuminate the interactions between Trichoderma and phytopathogens.…”
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    Endophytic Trichoderma gamsii YIM PH30019: a promising biocontrol agent with hyperosmolar, mycoparasitism, and antagonistic activities of induced volatile organic compounds on root-rot pathogenic fungi of Panax notoginseng
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