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12001por Chang, Huan, Li, Xin, Cai, Qian, Li, Chunyun, Tian, Lang, Chen, Jia, Xing, Xiaowei, Gan, Yu, Ouyang, Wen, Yang, Zuocheng“…This finding may serve as a clue to elucidate the function of autophagy at different times of infection. …”
Publicado 2017
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12002por Lipska-Ziętkiewicz, Beata S., Gellermann, Jutta, Boyer, Olivia, Gribouval, Olivier, Ziętkiewicz, Szymon, Kari, Jameela A., Shalaby, Mohamed A., Ozaltin, Fatih, Dusek, Jiri, Melk, Anette, Bayazit, Aysun K., Massella, Laura, Hyla-Klekot, Lidia, Habbig, Sandra, Godron, Astrid, Szczepańska, Maria, Bieniaś, Beata, Drożdż, Dorota, Odeh, Rasha, Jarmużek, Wioletta, Zachwieja, Katarzyna, Trautmann, Agnes, Antignac, Corinne, Schaefer, Franz“…In conclusion, while short stature is a reliable clue to SIOD in children with SRNS, other systemic features are highly variable. …”
Publicado 2017
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12003por Wu, Yue, Yu, Ru-Jing, Chen, Di, Xu, Li, Li, Mao, Zhu, Li, Guo, Chun-Yu, Guo, Wen-Yi“…The predominance of males in Sturge–Weber syndrome (SWS) early-onset glaucoma patients might be due to the limitation of the case number; however, it might also provide us a new clue of potential relationship between SWS and PCG.…”
Publicado 2017
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12004por Capkova, Pavlina, Santava, Alena, Markova, Ivana, Stefekova, Andrea, Srovnal, Josef, Staffova, Katerina, Durdová, Veronika“…CONCLUSION: An abnormal facial profile detected on prenatal scan can provide a clue to the presence of rare chromosomal abnormalities in the first trimester of pregnancy despite the normal result of the first trimester screening test. …”
Publicado 2017
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12005por Shim, Kang Hee, Kim, Tae Woo, Chung, Byung Ha, Lee, Sung Won, Park, Jong Kwan, Park, Kwangsung, Cheon, Jun, Lee, Kyung Seop, Kim, Hyung-Jee, Seong, Do-Hwan, Oh, Seung-June, Kim, Sae Woong, Lee, Ji Youl, Choo, Seol Ho, Choi, Jong Bo“…We suggest that this could be a clue to the importance of balance in autonomic nervous system activity in men with LUTS.…”
Publicado 2018
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12006por Liu, Wanting, Liu, Chaowu, Zhang, Li, Xie, Xiaofei, Gu, Xiaoqiong, Sang, Chuanlan, Xu, Mingguo, Xu, Weijun, Jia, Hongling“…Important proteins involved in the formation of the wound healing signaling network were identified via enriched biological processes and pathway analysis using ClueGo and ReactomeFIViz software. In the present study, 5 significantly differentially-expressed proteins, including mannose binding lectin 2 (MBL2), complement factor H (CFH), kininogen 1 (KNG1), serpin family C member 1 (SERPINC1) and fibronectin 1 (FN1), were selected and confirmed by western blotting. …”
Publicado 2018
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12007por Li, Yun, Wang, Shengpei, Pan, Chuxiong, Xue, Fushan, Xian, Junfang, Huang, Yaqi, Wang, Xiaoyi, Li, Tianzuo, He, Huiguang“…The purpose of this study is to compare them by in vivo human brain function to probe the neuromechanism of consciousness, so as to find out a clue to GA mechanism. METHODS: 24 healthy participants were equally assigned to sleep or propofol sedation group by sleeping ability. …”
Publicado 2018
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12008por Wang, Qianqian, Xu, Jiahui, Li, Ying, Huang, Jumin, Jiang, Zebo, Wang, Yuwei, Liu, Liang, Leung, Elaine Lai Han, Yao, Xiaojun“…This new binding site provides a new clue for the design and discovery of potent and specific PRMT5 inhibitors. …”
Publicado 2018
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12009por Bhattacharyya, Parthasarathi, Dasgupta, Sanjukta, Paul, Mintu, Saha, Dipanjan, Sengupta, Sayoni, Bhattacharyya, Pinak Pani“…METHODS: Chronic HP from exposure to avian antigen was diagnosed when the high resolution computerized tomography (HRCT) showed features for HP and was supported by the history of exposure to pigeons, the presence of precipitin antibodies (IgG) to avian antigen in high titre with negative rheumatoid factor, antinuclear antibody, and no clinical clue for a collagen vascular disease. The HRCT changes were noted on Likert scale (0–5) in terms of affection of peripheral and/or axial involvement, reticulation, honeycombing, haze, mosaic, traction bronchiectasis, pleural reactions, features of pulmonary hypertension, and air cysts. …”
Publicado 2018
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12010por Jiang, Lisheng, Zhang, Min, Zhang, Hong, Shen, Lan, Shao, Qin, Shen, Linghong, He, Ben“…CONCLUSIONS: Our results provided a clue that MB might act as a potential protective element against severe obstructive atherosclerosis in the whole coronary artery system.…”
Publicado 2018
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12011por Kridin, Khalaf, Khamaisi, Mogher, Comaneshter, Doron, Batat, Erez, Cohen, Arnon D.“…This study does not provide a clue for an association of pemphigus with Grave‘s disease or thyroid cancer.…”
Publicado 2018
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12012“…The appearance of large-scale cystic components may be an important clue for the diagnosis of BCA. PET/CT images were also available in one case. …”
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12013por Trutneva, Kseniya, Shleeva, Margarita, Nikitushkin, Vadim, Demina, Galina, Kaprelyants, Arseny“…This study provides a clue as to which biochemical processes could be active under dormancy to ensure long-term viability of dormant mycobacteria.…”
Publicado 2018
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12014“…The metabolic mechanisms that control 2HG metabolism in vivo are poorly understood. One clue towards how cells regulate 2HG levels has emerged from an inborn error of metabolism known as combined D- and L-2HG aciduria (D-/L-2HGA), which results in elevated D- and L-2HG accumulation. …”
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12015“…In addition, female-specific pleiotropy between TSH and fT4 might be a clue that this stronger genetic influences in females would mainly affect thyroid function per se, rather than other TSH-related factors that do not primarily trigger the negative feedback loop between TSH and fT4.…”
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12016por Gao, Cheng-Zhi, Dong, Wei, Cui, Zhi-Wen, Yuan, Qiong, Hu, Xia-Min, Wu, Qing-Ming, Han, Xianlin, Xu, Yao, Min, Zhen-Li“…For pursuit of PARP-1 and BChE dual-targeted inhibitors against AD, small and flexible non-polar groups introduced to the compound seemed to be conducive to improving its inhibitory potency on huBChE, while keeping phthalazine-1-one moiety unchanged which was mainly responsible for PARP-1 inhibitory activity. Our research gave a clue to search for new agents based on AChE and PARP-1 dual-inhibited activities to treat Alzheimer’s disease.…”
Publicado 2018
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12017MicroRNA 486-3p directly targets BIK and regulates apoptosis and invasion in colorectal cancer cellspor Feng, Li, Jing, Li, Han, Jing, Wang, Guiying, Liu, Yan, Zhang, Xue, Wang, Yudong, Wang, Feifei, Ma, Hongqing, Liu, Yibing“…Gene therapy using miR486-3p inhibition may provide a new clue for CRC therapy.…”
Publicado 2018
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12018por Staffolani, Silvia, Buonfrate, Dora, Angheben, Andrea, Gobbi, Federico, Giorli, Giovanni, Guerriero, Massimo, Bisoffi, Zeno, Barchiesi, Francesco“…The infection can mimic other diseases, and the epidemiological risk of exposure is an important clue to raise the index of suspicion. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12879-018-3476-z) contains supplementary material, which is available to authorized users.…”
Publicado 2018
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12019por Moscoso, Ana, Speranza, Mario, Delvenne, Veronique, Corcos, Maurice, Pham-Scottez, Alexandra“…This could be useful in clinical practice as an early clue to identify patients with potentially severe clinical profiles and parents needing a specific support. …”
Publicado 2019
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12020“…Despite several limitations, these findings may provide auxiliary information to further explain the mechanisms of AVHs and provide a clue for scholars to further explore specific treatment targets for AVHs in Hi-AVH subjects or in schizophrenia patients.…”
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