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  1. 12021
    “…The present study gives a strong clue for the association of Prakriti (body constitutional) and clinical phenotype.…”
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    Association of Kaphaja and Kapha-Pittaja Prakriti and methylenetetrahydrofolate reductase C677T allele with type 2 diabetes
  2. 12022
    “…In a number of compatible plant‐bacterium interactions, a rise in apoplastic Ca(2+) levels is observed, suggesting that Ca(2+) represents an important environmental clue, as reported for bacteria infecting mammalians. …”
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    A Na(+)/Ca(2+) exchanger of the olive pathogen Pseudomonas savastanoi pv. savastanoi is critical for its virulence
  3. 12023
    “…Hemorrhagic manifestations and low platelet count provide a clue to early detection of disease. Vaginal bleeding can be a sign of CCHF and needs immediate action.…”
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    Investigation of Crimean-Congo hemorrhagic Fever in Patients Admitted in Antani Hospital, Kabul, Afghanistan, 2017–2018
  4. 12024
    “…Knowledge of clinical presentation and age-related variations among seasonal viruses may give a clue about severe course and prognosis. By presenting the analyzed data of 302 PICU admissions, current study reveals severity of viral respiratory tract infections and release tips for handling them. …”
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    Comprehensive Analysis of Severe Viral Infections of Respiratory Tract admitted to PICUs during the Winter Season in Turkey
  5. 12025
    “…Our study provides potential clue to further complete the intrinsic mechanism of Puerarin in treating osteoporosis.…”
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    Online Artículo Texto
    Puerarin inhibits the osteoclastogenesis by inhibiting RANKL-dependent and –independent autophagic responses
  6. 12026
    “…These findings suggested a genetic clue for exploring the underlying molecular basis and pathogenesis of IPF.…”
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    Online Artículo Texto
    The relationship between MUC5B promoter, TERT polymorphisms and telomere lengths with radiographic extent and survival in a Chinese IPF cohort
  7. 12027
    “…CONCLUSION: When CTA shows the spot sign in a ventricle, it is a clue that an existing underlying vascular lesion requires endovascular treatment.…”
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    The Role of digital subtraction angiography in the ventricular spot sign on the computed tomography angiography
  8. 12028
    “…We also constructed a phylogenetic tree to compare the homology and variation of FMD virus (FMDV) to provide a clue for the potential development of an effective vaccine. …”
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    Retrospect and Risk Analysis of Foot-and-Mouth Disease in China Based on Integrated Surveillance and Spatial Analysis Tools
  9. 12029
    “…Approaches like CoRIA and COMBINE can use information generated from the ligand–receptor complexes to extract the critical clue concerning the types of significant interaction at the level of both the receptor and the ligand. …”
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    Other Related Techniques
  10. 12030
    “…These findings provided a novel clue for new strategies of AD therapy via targeting endogenous opioid receptors.…”
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    Online Artículo Texto
    Opposite Roles of δ- and μ-Opioid Receptors in BACE1 Regulation and Alzheimer’s Injury
  11. 12031
    “…Based on the consistency in expression status of host factors in different cell types and previous evidence reported in the literature, pro-viral factors of SARS-CoV-2 identified and subject to drug repurposing analysis based on DrugBank and Connectivity Map (CMap) using the web tool, CLUE. RESULTS: The upregulated pro-viral factors such as TYMP, PTGS2, C1S, CFB, IFI44, XAF1, CXCL2, and CXCL3 were identified in early infection models of SARS-CoV-2. …”
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    Host transcriptome-guided drug repurposing for COVID-19 treatment: a meta-analysis based approach
  12. 12032
    “…Overall, the work can provide a better understanding of the therapeutic mechanism of SFJDC for treating SARS-CoV-2 pneumonia from multi-scale perspectives, and may also offer a valuable clue for developing novel pharmaceutical strategies to control the current coronavirus.…”
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    Systematic analyses on the potential immune and anti-inflammatory mechanisms of Shufeng Jiedu Capsule against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-caused pneumonia
  13. 12033
    “…Our results may provide a novel therapeutic clue of promoting bone fracture healing.…”
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    The neurofibromatosis type I gene promotes autophagy via mTORC1 signalling pathway to enhance new bone formation after fracture
  14. 12034
    por Warkentin, Theodore E.
    Publicado 2020
    “…Recent recognition of “SRA-negative HIT” has increased the importance of semiquantitative interpretation of immunoassays, given that strong immunoassay reactivity is a potential clue indicating possible HIT despite a (false) negative platelet activation assay.…”
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    Challenges in Detecting Clinically Relevant Heparin-Induced Thrombocytopenia Antibodies
  15. 12035
    “…The findings may provide a clue for understanding the responses of genes and networks to environmental temperature.…”
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    Online Artículo Texto
    Early response to heat stress in Chinese tongue sole (Cynoglossus semilaevis): performance of different sexes, candidate genes and networks
  16. 12036
    “…Five target pairs of DElncRNA-DEmRNA, namely, ENSCHIT00000001255-OTX2, ENSCHIT00000006005-PEG3, ENSCHIT00000009455-PIWIL3, ENSCHIT00000007977-POMP, and ENSCHIT00000000834-ACTR3 in co-expression analysis provide a clue in follicular development and maturation of lncRNA-mRNA interaction. …”
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    Online Artículo Texto
    Identification of mRNAs and lncRNAs Involved in the Regulation of Follicle Development in Goat
  17. 12037
    “…BACKGROUND: The cellular response to nanoparticles (NPs) for the mechanical clue and biochemical changes are unexplored. Here, we provide the comprehensive analysis of the Chinese Hamster Ovary (CHO-K1) cell line to study cell behaviour following the exposure of mesoporous silica nanoparticle (MSN), multiwall carbon nanotubes (MWCNTs), and zinc oxide (ZnO) NPs. …”
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    MSN, MWCNT and ZnO nanoparticle-induced CHO-K1 cell polarisation is linked to cytoskeleton ablation
  18. 12038
    “…Our results may provide a fundamental clue for understanding the genetic mechanisms of AMI.…”
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    Integrative Analysis of Transcriptome-Wide Association Study and mRNA Expression Profiles Identified Candidate Genes and Pathways Associated With Acute Myocardial Infarction
  19. 12039
    “…Recent studies have demonstrated promising safety and clinical efficacy of allogeneic ‘off-the-shelf’ virus-specific T-cell therapies for post-transplant viral complications. METHODS: Taking a clue from these studies, we developed a highly efficient EBV-specific T-cell expansion process using a replication-deficient AdE1-LMPpoly vector that specifically targets EBV-encoded nuclear antigen 1 (EBNA1) and latent membrane proteins 1 and 2 (LMP1 and LMP2), expressed in latency II malignancies. …”
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    'Off-the-shelf’ allogeneic antigen-specific adoptive T-cell therapy for the treatment of multiple EBV-associated malignancies
  20. 12040
    “…This study confirmed potent antidiabetic and superior antioxidant potential of the newly synthesized Schiff base (P3), which could ultimately account for insulin sensitization and for cellular protection and hence provide a potential clue for dual therapeutics.…”
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    Schiff Bases of Pioglitazone Provide Better Antidiabetic and Potent Antioxidant Effect in a Streptozotocin–Nicotinamide-Induced Diabetic Rodent Model
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