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12141por Lin, Shuyan, Shao, Lijuan, Hui, Cang, Song, Yu, Reddy, Gadi V. P., Gielis, Johan, Li, Fang, Ding, Yulong, Wei, Qiang, Shi, Peijian“…The findings provide the insights on the evolutionary clue about the biomass investment and output of photosynthetic organs of plants. …”
Publicado 2018
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12142por Suh, Sung-Suk, Hong, Ju-Mi, Kim, Eun Jae, Jung, Seung Won, Kim, Sun-Mi, Kim, Jung Eun, Kim, Il-Chan, Kim, Sanghee“…Taken together, our findings suggest that the anti-inflammatory and anticancer activities of the Antarctic freshwater microalga, Micractinium sp., and ETMI may provide a new clue for understanding the molecular link between inflammation and cancer and that ETMI may be a potential anticancer agent for targeted therapy of colorectal cancer.…”
Publicado 2018
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12143por Tominaga, Naomi, Kanazawa, Naomi, Kaneko, Atsushi, Kaneko, Juntaro, Kitamura, Eiji, Nakagawa, Hiroto, Nishiyama, Kazutoshi, Iizuka, Takahiro“…Psychobehavioral alterations following headache is an important clue to the diagnosis.…”
Publicado 2018
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12144por Li, Jing, Zuo, Zhentao, Zhang, Xuewei, Shao, Xiali, Lu, Jie, Xue, Rong, Fan, Yong, Guan, Yuzhou, Zhang, Weihong“…Conclusion: The greater connectivity of contralesional cortico-cerebellar loop and the strengthening of interhemispheric connection may reflect contralesional compensation facilitated by the excitatory rTMS, which gives us a clue to understand the therapeutic mechanism of rTMS.…”
Publicado 2018
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12145por Muke, Suraj, Kaikini, Aakruti, Peshattiwar, Vaibhavi, Bagle, Sneha, Dighe, Vikas, Sathaye, Sadhana“…According to Ayurvedic philosophy, the juice of leaves of EA is pounded with garlic and pepper for the treatment of epilepsy. Taking clue from the Ayurvedic system of medicines, we formulated coumarin fraction of EA, namely, coumarin nasal formulation (CNF) for its nasal delivery. …”
Publicado 2018
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12146por Taherkhani, Amir, Kalantari, Shiva, Oskouie, Afsaneh Arefi, Nafar, Mohsen, Taghizadeh, Mohammad, Tabar, Koorosh“…In addition, a protein-protein interaction (PPI) network, which was based on proteins associated with MGN, was built and analyzed using PPI analysis methods, including molecular complex detection and ClueGene Ontology. A total of 26 metabolites were identified as hub nodes in the CREG network, 13 of which had salient centrality and fold-changes: Dopamine, carnosine, fumarate, nicotinamide D-ribonucleotide, adenosine monophosphate, pyridoxal, deoxyguanosine triphosphate, L-citrulline, nicotinamide, phenylalanine, deoxyuridine, tryptamine and succinate. …”
Publicado 2018
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12147por He, Dan, Li, Qian, Xu, Guangjin, Hu, Zheng, Li, Xuefei, Guo, Yinping, Xu, Shabei, Wang, Wei, Luo, Xiang“…The results of our study indicate that the infarct patterns might be a clue of PFO‐related stroke.…”
Publicado 2018
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12148“…Thus, this study may give a valuable clue for further exploring the miRNA group that may function during pollen development. …”
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12149“…R/Bioconductor package limma was used to screen differently expressed genes (DEGs). ClueGO of cytoscape was applied for Gene Ontology (GO) functional and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment. …”
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12150“…Conclusion: It has not been clearly identified that integrative therapy with KM and biomedicine for PD management is better treatment for patients compared to biomedicine monotherapy; however, we found a clue of better result in integrated therapy. Therefore, further investigation by increasing the number of subjects is needed to confirm the findings presented herein.…”
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12151“…However, the recent discovery of a signalling pathway built into the type III systems of class 1 might offer a clue, suggesting that type III effector modules could have evolved from a signal transduction system involved in stress-induced programmed cell death. …”
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12152por Zhang, Jian, Zheng, Chenglong, Yuan, Siyuan, Dong, Xiaoke, Wang, Le, Wang, Yong, Wang, Wei, Gao, Kuo, Liu, Jinmin“…After identifying epileptic targets of CZD, their interaction with other proteins was estimated based on protein-protein interaction network created from STITCH and gene ontology (GO) enrichment analysis utilizing Cytoscape-ClueGO plugin. RESULTS: CZD formula was found to have 643 chemical ingredients, and the potential protein targets of these ingredients were 5230, as retrieved from TCMSP database. …”
Publicado 2019
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12153por Garai, Preeti, Berry, Laurence, Moussouni, Malika, Bleves, Sophie, Blanc-Potard, Anne-Béatrice“…Concordantly, cyclic di-GMP (c-di-GMP) level was increased in both mutants, providing a clue for negative regulation of T3SS inside macrophages. …”
Publicado 2019
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12154por Chopra, Ajay, Mitra, Debdeep, Agarwal, Reetu, Saraswat, Neerja, Talukdar, Krishna, Solanki, Abhay“…Leprosy reactions were characterized by blood vessel changes and arborizing blood vessels were characteristic in erythema nodosum leprosum, and a diffuse erythema was a clue toward diagnosing type I lepra reaction. Interestingly, clofazimine-induced pigmentation was picked up characteristically on dermoscopy as a “honey comb pattern”. …”
Publicado 2019
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12155por Suzuki, Keiji, Akita, Sadanori, Yoshimoto, Hiroshi, Ohtsuru, Akira, Hirano, Akiyoshi, Yamashita, Shunichi“…Among them, adipose-derived stem/progenitor cells (ADSCs)-based therapy could be the most promising clue, since ADSCs have pluripotent differentiation capabilities not only in adipocytes but also in a variety of cell types. …”
Publicado 2019
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12156por Diani, Marco, Perego, Silvia, Sansoni, Veronica, Bertino, Lucrezia, Gomarasca, Marta, Faraldi, Martina, Pigatto, Paolo Daniele Maria, Damiani, Giovanni, Banfi, Giuseppe, Altomare, Gianfranco, Lombardi, Giovanni“…By highlighting never exploited differences, the wide osteoimmunological biomarkers panel provides a novel clue to the development of diagnostic paths in psoriasis and psoriasis-associated arthropathic disease.…”
Publicado 2019
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12157por Toyoda, Ayano, Kozaki, Toshinori, Ishii, Kazuo, Taniishi, Momoka, Hattori, Makoto, Matsuda, Hiroshi, Yoshida, Tadashi“…This study would contribute to providing a novel clue to the fine understanding of the mechanism for T cell anergy and oral tolerance.…”
Publicado 2020
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12158por Li, Qun, Shen, Zhisen, Wu, Zhenhua, Shen, Yi, Deng, Hongxia, Zhou, Chongchang, Liu, Huigao“…Then, KEGG analysis of P4HA1 co‐expressed genes in HNSCC was conducted using ClueGo in Cytoscape. RESULTS: P4HA1 mRNA and protein levels were significantly increased in HNSCC tissues compared with normal tissues. …”
Publicado 2019
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12159“…In the first sub-step (of both steps), our programs automatically generate training data using an emotion-oriented, clue-based method. In the second sub-step, we are training and testing three different Machine Learning (ML) models with the training data from the first sub-step; this allows us to determine the best ML model for different datasets. …”
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12160“…The diagnosis may be at your fingertips; therefore a thorough skin exam is the clue. However, it’s also important to know the characteristic lesions associated with different infections. …”
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