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  1. 12261
    “…CONCLUSIONS: We identified five DNA methylation-regulated genes based on a predictive model for CHD using machine learning, which may clue the new epigenetic mechanism for CHD. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13148-022-01343-2.…”
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    Identification of DNA methylation-regulated genes as potential biomarkers for coronary heart disease via machine learning in the Framingham Heart Study
  2. 12262
    “…Our findings might provide a clue for the molecular evolution of the four HCoVs and help in the early diagnosis, treatment and prevention of broad-spectrum HCoV infection.…”
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    Molecular evolution of human coronavirus-NL63, -229E, -HKU1 and -OC43 in hospitalized children in China
  3. 12263
    “…As immune protection is arisen from our blood cells, assessing their level will provide a clue for controlling the disease and monitoring the prognosis. …”
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    Hematological Profiles and Clinical Outcome of COVID-19 Among Patients Admitted at Debre Markos Isolation and Treatment Center, 2020: A Prospective Cohort Study
  4. 12264
    “…Expensive molecular testing can give a clue to the possibility of malignancy in this group. …”
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    Serum TSH Level as a Simple Efficient Tool to Assess the Risk of Thyroid Malignancy in Euthyroid Patients with Indeterminate Cytology - A Cohort Study
  5. 12265
    “…These results provide a useful clue for a clinical strategy to prevent PF.…”
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    Metformin attenuates fibroblast activation during pulmonary fibrosis by targeting S100A4 via AMPK-STAT3 axis
  6. 12266
    “…Therefore, there is a need to devise a synchronizing program that can improve conception, allow early pregnancy diagnosis, reduce early embryonic losses, and provide an early clue for pregnancy diagnosis and establishment. The present study aimed (1) to determine the effect of administration of different GnRH doses at day 20 of artificial insemination (AI) on the reproductive performance of buffaloes and (2) to observe the influence of synchronization protocol, parity, age, milk production, and body condition score (BCS) on early embryonic loss and progesterone (P4) levels in crossbred buffaloes. …”
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    Administration of GnRH at day 20 of AI and embryonic losses in synchronized crossbred buffalo
  7. 12267
    por Bixby, Daniel W
    Publicado 2018
    “…Unfortunately, most them have little or no prior experience or training in adult education and don't have a clue about how to transfer their knowledge to others. …”
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    Product training for the technical expert: the art of developing and delivering hands-on learning
  8. 12268
    “…Our results can provide an important clue in the treatment of certain skin diseases. The research of the skin microbiome during balneotherapy can be one of the most intriguing and exciting topics of the future and can bring us closer to understanding the mechanism of action of balneotherapy.…”
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    The Effects of Lakitelek Thermal Water and Tap Water on Skin Microbiome, a Randomized Control Pilot Study
  9. 12269
    “…CONCLUSION: Thus, the macrophage phenotype is a prognostic indicator in PROC patients, possibly via a hyperactive IL-6-related pathway, providing an additional clue for the therapeutic intervention of PROC.…”
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    Macrophages Phenotype Regulated by IL-6 Are Associated with the Prognosis of Platinum-Resistant Serous Ovarian Cancer: Integrated Analysis of Clinical Trial and Omics
  10. 12270
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    Social Vulnerability and Risk of Suicide in US Adults, 2016-2020
  11. 12271
    “…The relationships among microbial activities, abundances, and environmental conditions improve our understanding of the regulatory mechanisms of microbial activities in cyanobacterial aggregates and also provide a novel clue for studying determinants of microbial activities in other ecosystems.…”
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    Determinants of Total and Active Microbial Communities Associated with Cyanobacterial Aggregates in a Eutrophic Lake
  12. 12272
    “…These results may provide a clue to CTS pathogenesis.…”
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    Morphologic classification of tracheobronchial arborization in children with congenital tracheobronchial stenosis and the associated cardiovascular defects
  13. 12273
    “…The discovery of blapstin provides a novel clue for our understanding of the innate immunity of Blaps rhynchopetera and provides a template for designing antifungal drugs.…”
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    Blapstin, a Diapause-Specific Peptide-Like Peptide from the Chinese Medicinal Beetle Blaps rhynchopetera, Has Antifungal Function
  14. 12274
    “…Our study provides a new clue for the regulatory mechanism of carotenoid metabolism in Dunaliella. …”
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    Roles of Two Phytoene Synthases and Orange Protein in Carotenoid Metabolism of the β-Carotene-Accumulating Dunaliella salina
  15. 12275
    “…This result could provide a clue for the novel approach to the prevention and treatment of GI cancers. …”
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    Allergic Diseases and Risk of Malignancy of Gastrointestinal Cancers
  16. 12276
    “…To sum up, these findings provide a crucial clue for screening key vector factors involved in the process of virus circulation in aphids and exploring the molecular mechanism of transmission of BrYV by the green peach aphid. …”
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    Transcriptomic and Proteomic Analyses of Myzus persicae Carrying Brassica Yellows Virus
  17. 12277
    “…The identification of several SMPs as novel potential substrates of RseP provides a clue to a comprehensive understanding of the cellular roles of RseP and other S2P peptidases and highlights a novel aspect of the regulation of SMPs. …”
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    S2P intramembrane protease RseP degrades small membrane proteins and suppresses the cytotoxicity of intrinsic toxin HokB
  18. 12278
    por Deacy, Anthony M, Gan, Samuel Ken-En
    Publicado 2023
    “…These in vitro measurements provide a clue to detailed antibody engineering and understanding of antibody superantigen functions that would be relevant with in vivo validation.…”
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    The influence of variable-heavy chain families on IgG(2), (3), (4), FcγRs and B-cell superantigens protein G and L binding using biolayer interferometry
  19. 12279
    por Ming, Li, Wang, Duan, Zhu, Yong
    Publicado 2023
    “…To sum up, we have provided the clue to the etiology of diabetes and further prospective research is needed to contribute recommendations for the primary prevention of diabetes in the US.…”
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    Association of sodium intake with diabetes in adults without hypertension: evidence from the National Health and Nutrition Examination Survey 2009–2018
  20. 12280
    “…Weighted gene co-expression network analysis is used to identify the co-expression modules related to PF and PH. We used the ClueGO software to enrich and analyze the common genes in PF and PH and obtained the protein–protein interaction (PPI) network. …”
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    Identification of the shared gene signatures between pulmonary fibrosis and pulmonary hypertension using bioinformatics analysis
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