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12321por Breton, Quentin, Plouhinec, Hélène, Prunier‐Mirebeau, Delphine, Boisselier, Blandine, Michalak, Sophie, Menei, Philippe, Rousseau, Audrey“…INTRODUCTION: Some glial–neuronal tumors (GNT) (pleomorphic xantho‐astrocytoma [PXA], ganglioglioma [GG]) display BRAF‐V600E mutation, which represents a diagnostic clue to these entities. Targeted therapies against BRAF‐V600 protein have shown promising results in GNT. …”
Publicado 2017
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12322por Yoshikawa, Rokusuke, Takeuchi, Junko S., Yamada, Eri, Nakano, Yusuke, Misawa, Naoko, Kimura, Yuichi, Ren, Fengrong, Miyazawa, Takayuki, Koyanagi, Yoshio, Sato, Kei“…Our findings can be a clue to elucidate the complicated evolutionary processes by which lentiviruses adapt to mammals.…”
Publicado 2017
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12324“…His slender body shape, hyperflexible joints, and hyperextensible skin provided clue to suspicion of a possible connective tissue disorder. …”
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12326“…Subsequently, Gene Ontology (GO) function and Kyoto Encyclopaedia of Genes and Genomes (KEGG) pathway enrichment analyses of the top module of the PPI network were performed by using ClueGo. A total of 377 DEGs were identified in the synovial membranes of OA patients compared with those of normal individuals, including 164 upregulated and 213 downregulated genes. …”
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12327por Ono, Seijiro, Liu, Hua, Tsuda, Katsutoshi, Fukai, Eigo, Tanaka, Keisuke, Sasaki, Takuji, Nonomura, Ken-Ichi“…Spatiotemporal expression control of these bHLH proteins is a clue to orchestrate precise meiosis progression and subsequent pollen production non-cell-autonomously.…”
Publicado 2018
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12328por Rekhtman, Natasha, Pietanza, Catherine M., Sabari, Joshua, Montecalvo, Joseph, Wang, Hangjun, Habeeb, Omar, Kadota, Kyuichi, Adusumilli, Prasad, Rudin, Charles M., Ladanyi, Marc, Travis, William D., Joubert, Philippe“…The combination of TTF-1-diffuse/napsin A-negative or focal was typical of LCNEC but was rare in adenocarcinoma, and could thus serve as a helpful diagnostic clue. The diagnosis of napsin A-positive LCNECs was confirmed by classic morphology, diffuse labeling for at least one neuroendocrine marker, most consistently synaptophysin, and the lack of distinct adenocarcinoma component. …”
Publicado 2017
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12329“…An attempt has been made here to evaluate clinical and imaging features (ultrasound and renal dynamic scan [RDS]) in children of PUJO with CLPV and define variables that could provide a diagnostic clue to its presence. MATERIALS AND METHODS: Records of children having PUJO with CLPV over 10 years (2006–2015) were reviewed retrospectively. …”
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12330por An, Kyung-min, Ikeda, Takashi, Yoshimura, Yuko, Hasegawa, Chiaki, Saito, Daisuke N., Kumazaki, Hirokazu, Hirosawa, Tetsu, Minabe, Yoshio, Kikuchi, Mitsuru“…Our findings provide an important clue into the behavioral and neurophysiological alterations in autism and a potential biomarker for autism. …”
Publicado 2018
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12331por Zhu, Jingxuan, Li, Yi, Wang, Jinzhi, Yu, Zhengfei, Liu, Ye, Tong, Yi, Han, Weiwei“…The theoretical results illustrated the reasons that Y68I/G109P mutations increased the catalytic efficiency of CbDPEase and could be provided the new clue for further DPEase engineering.…”
Publicado 2018
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12332por Montembeault, Maxime, Brambati, Simona M., Lamari, Foudil, Michon, Agnès, Samri, Dalila, Epelbaum, Stéphane, Lacomblez, Lucette, Lehéricy, Stéphane, Habert, Marie-Odile, Dubois, Bruno, Kas, Aurélie, Migliaccio, Raffaella“…Additional fronto-temporal (especially dorsolateral prefrontal) damage seems to be a clue to underlying non-AD pathology in PCA, which warrants the need for longitudinal follow-ups to investigate frontal symptoms in these patients.…”
Publicado 2018
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12333“…Our findings propose a clue for further studies with this compound in preclinical and clinical treatment for OS.…”
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12334por Nomura, Koutatsu, Ajiro, Yoichi, Nakano, Satomi, Matsushima, Maiko, Yamaguchi, Yuki, Hatakeyama, Nahoko, Ohata, Mari, Sakuma, Miyuki, Nonaka, Terumi, Harii, Miyuki, Utsumi, Masafumi, Sakamoto, Kazuhiro, Iwade, Kazunori, Kuninaka, Nobuo“…This finding might provide a clue regarding the etiology of mitral valve prolapse in PE at its possible earliest form.…”
Publicado 2019
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12335por Xiao, Wei‐Yuan, Zong, Zhen, Qiu, Man‐Le, Chen, Xiu‐Yuan, Shen, Hong‐Xing, Lao, Li‐Feng“…Quantitative real‐time polymerase chain reaction was used to verify the accuracy of some differentially expressed genes (DEG). ClueGO was used to decode and visualize functionally grouped GO terms of differentially expressed genes, and to map the DEG protein–protein interactions (PPI) network. …”
Publicado 2018
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12336por Chen, Xike, Yamashita, Akihiro, Morioka, Miho, Senba, Toshika, Kamatani, Takashi, Watanabe, Akira, Kosai, Azuma, Tsumaki, Noriyuki“…The findings contribute to understanding how hiPS-Carts form repair tissue and provide clue to accelerate healing after transplantation.…”
Publicado 2019
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12337“…The eschar is a useful diagnostic clue and febrile patients without any localizing signs should be thoroughly examined for its presence.…”
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12338por Chen, Hongqin, Zhang, Yanping, Dai, Li, Song, Yaping, Wang, Yanyun, Zhou, Bin, Zhou, Rong“…These data provide a new clue for future investigation.…”
Publicado 2019
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12339por Chai, Tianci, Shen, Zhimin, Zhang, Peipei, Lin, Yuhan, Chen, Sui, Zhang, Zhenyang, Lin, Wenwei, Kang, Mingqiang, Lin, Jiangbo“…CONCLUSION: The results of this systematic review and meta-analysis will provide a basis for clinicians to formulate the best chemotherapy regimen for patients, as well as a research clue for clinical researchers in this field. The results of this study will expand the treatment options for esophageal patients, but due to the nature of the disease and intervention, large sample clinical trials are not abundant, so we will include some high-quality small sample trials, which may cause high heterogeneity. …”
Publicado 2019
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12340“…Next, we input all key targets into ClueGO plugin for KEGG enrichment and molecular function analyses. …”
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