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  1. 12581
    “…Functional enrichment analysis from Ingenuity® Pathway Analysis (IPA®), ClueGO application and STRING of these modules was performed to identify relevant biological pathways and regulatory genes. …”
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    Gene co-expression networks from RNA sequencing of dairy cattle identifies genes and pathways affecting feed efficiency
  2. 12582
    “…In comparison to what is found in patients with non-autoimmune MTL epilepsy, insular hypometabolism is observed only in patients with GAD ab, so it may be an important diagnostic clue.…”
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    Hippocampus and Insula Are Targets in Epileptic Patients With Glutamic Acid Decarboxylase Antibodies
  3. 12583
    “…These findings suggest that dogs with gallbladder mucocele formation have a greater capacity for cortisol synthesis and pinpoint DHEAS elevations as a potential clue to the underlying pathogenesis of the disease. …”
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    Investigation of adrenal and thyroid gland dysfunction in dogs with ultrasonographic diagnosis of gallbladder mucocele formation
  4. 12584
    “…Multiple punctate calcifications were present in pools of extracellular mucin, a diagnostic clue for mucinous adenocarcinoma. Possible mechanisms underlying scattered punctuate calcifications in gastric mucinous adenocarcinoma warrant further investigation.…”
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    Calcified mucinous adenocarcinoma of the stomach metastatic to the iris: a case report
  5. 12585
    “…Hence, our results have revealed the structural roles of N-terminal fragment of PCV2 capsid protein in PCV2 particle assembly and pinpointed one PCV2 type-specific neutralizing epitope for the first time, which could provide clear clue for next generation PCV2 vaccine and diagnostic kits development.…”
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    Structural roles of PCV2 capsid protein N-terminus in PCV2 particle assembly and identification of PCV2 type-specific neutralizing epitope
  6. 12586
    “…The differential distribution of CD8+ and FOXP3+ TILs in LyP as compared to pcALCL could provide a clue to the relapsing/remitting course of LyP as compared to the less frequent spontaneous regression of pcALCL.…”
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    Clinicopathologic and microenvironmental analysis of primary cutaneous CD30-positive lymphoproliferative disorders: a 26 year experience from an academic medical center in Brazil
  7. 12587
    “…Although malignant and benign pheochromocytoma share the same clinical and histological features, the presence of metastasis is the main clue to differentiate them. Surgery remains the main treatment option even if complete debulking cannot be achieved. …”
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    SUN-902 Bradycardia as a Presentation of Malignant Pheochromocytoma
  8. 12588
    “…This study provides a clue that identified pregnancy-stage specific microarray transcript probes could be considered as candidate genes for recognition and establishment of early pregnancy in the pig.…”
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    Identification of Differentially Expressed Gene Transcripts in Porcine Endometrium during Early Stages of Pregnancy
  9. 12589
    “…The frequency of these impairments and their specificity as a potential central nervous system function biomarker are of great interest as a diagnostic clue for CoViD-19 infection as opposed to other similar symptomatologic diseases and because of their implication in viral pathogenesis. …”
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    Smell and Taste in Severe CoViD-19: Self-Reported vs. Testing
  10. 12590
    “…These provide healthcare providers in the ED an immediate clue regarding the patient’s illness.…”
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    Association Between the Simplest Clinical Factors and Emergency Department Dispositions: A Retrospective Observational Study
  11. 12591
    “…Considering the prominent role of PD-L1 in tumor immune evasion, our study provides an additional clue on how PD-L1 is regulated in aggressive breast cancer cells and pave the way to assess the therapeutic benefit of EMT inhibitors in combination with anti PD-L1 blockade in highly aggressive breast cancer patients. …”
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    Epithelial to Mesenchymal Transition Regulates Surface PD-L1 via CMTM6 and CMTM7 Induction in Breast Cancer
  12. 12592
    “…The presence of SIAD could be a clue to diagnosing COVID-19. SIAD is a major complication of COVID-19 and could be the first and only manifestation. …”
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    A Case of Inappropriate Antidiuretic Hormone Secretion Syndrome Associated With COVID-19 Pneumonia Treated With Boluses of Hypertonic Saline for Reversal of Symptomatic Hyponatremia
  13. 12593
    “…To make the most of the network, we used the CLUE database to predict potential drugs for the treatment of osteosarcoma based on mRNA expression in the network. …”
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    Construction of a circRNA-miRNA-mRNA Regulatory Network Reveals Potential Mechanism and Treatment Options for Osteosarcoma
  14. 12594
    “…In the current armamentarium, we have various biomarkers such as procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP), CRP, and band cell percentage for an early clue. AIMS: This study explores the accuracy of these markers in distinguishing sepsis from systemic inflammatory response syndrome (SIRS) and their correlation with sequential organ failure assessment (SOFA) scoring in critically ill patients. …”
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    Diagnostic Accuracy of Various Biomarkers of Sepsis (Serum Pro-Calcitonin, High-Sensitivity C-reactive Protein, and C-reactive Protein) and Band Cell Percentage in Critically lll Patients: A Prospective, Observational, Cohort Study
  15. 12595
    “…Our findings provide a new clue to understand the functions of ASFV-encoded pMGF505-7R and its role in viral infection-induced pathogenesis, which might help design antiviral agents or live attenuated vaccines to control ASF.…”
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    pMGF505-7R determines pathogenicity of African swine fever virus infection by inhibiting IL-1β and type I IFN production
  16. 12596
    “…For E gene and N gene, Remdesivir showed IC(50) of 0.15 µM and 0.11 µM respectively, For E gene and N gene, E4 showed IC(50) of 1.18 µg and 1.16 µg respectively. Taking the clue from in vitro findings, the E4, E5 and E2 were combined (E 4.5.2) and evaluated for acute and sub-acute toxicity in Wistar male and female rats. …”
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    In silico, in vitro screening of plant extracts for anti-SARS-CoV-2 activity and evaluation of their acute and sub-acute toxicity
  17. 12597
    “…This study extended our understanding of Xcc genomic features and provided the foundation to further characterize the mechanisms for Xcc virulence and a clue for black rot resistance breeding.…”
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    Comparative Genomic Analysis of Xanthomonas campestris pv. campestris Isolates BJSJQ20200612 and GSXT20191014 Provides Novel Insights Into Their Genetic Variability and Virulence
  18. 12598
    “…The network visualization analysis was performed by Cytoscape 3.7.1, which contains ClueGO plug-in for GO and KEGG analysis. In vivo experiments were performed on 40 male SD rats, which were randomly divided into the control group (n = 10), sham group (n = 10), UUO group (n = 10), and CCYSD group (n = 10). …”
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    Network Pharmacology and Experimental Validation to Reveal the Pharmacological Mechanisms of Chongcaoyishen Decoction Against Chronic Kidney Disease
  19. 12599
    “…Our finding of decreased mitochondrial ATP synthetic function selectively in residual white myofibres provides both a possible clue to understanding the apparent vulnerability of this particular fibre type in 5q spinal muscular atrophy types 3 and 4 as well as a new biomarker and target for therapy.…”
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    Magnetic resonance reveals mitochondrial dysfunction and muscle remodelling in spinal muscular atrophy
  20. 12600
    “…Then the function of genes in the three core networks was further analyzed with ClueGo and they were mainly enriched in six groups of biological processes. …”
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    Transcriptome Integration Analysis at Different Embryonic Ages Reveals Key lncRNAs and mRNAs for Chicken Skeletal Muscle
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