“…Citing clear examples of other public health successes and failures, we outline in detail how sustaining cardiovascular population health under complex post-pandemic conditions will necessitate decision-making to be informed with a systems science approach, in which interventions, goals, outcomes and features of complex systems are carefully aligned.…”
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“…Tumours are complex systems with dynamic interactions between tumour cells, non-tumour cells, and extracellular components that comprise the tumour microenvironment (TME). …”
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“…However, high-resolution rovibronic spectroscopy has been limited to relatively small and simple systems because translationally and rotationally cold samples have not been prepared in sufficiently large quantities for large and complex systems. In this study, we present high-resolution rovibronic spectroscopy results for large gas-phase molecules, namely, free-base phthalocya-nine (FBPc). …”
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“…The robust agreement between experiments and simulations makes the present study a fundamental step to establish this high-resolution monitoring technique as a platform for investigating more complex systems, these being either macromolecules with peculiar internal structure or nanocomplexes where molecules of interest can be encapsulated in the microgel network and controllably released with temperature.…”
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“…Complex systems can exhibit sudden transitions or regime shifts from one stable state to another, typically referred to as critical transitions. …”
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“…Such a spontaneous coupling of the so far independent degrees of freedom can be interpreted as a kind of phase transition that resembles the collective phenomena typical for the complex systems. Our results indicate that the cryptocurrencies cannot be considered as a safe haven for the financial investments.…”
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“…Computational models have become a powerful tool in the quantitative sciences to understand the behavior of complex systems that evolve in time. However, they often contain a potentially large number of free parameters whose values cannot be obtained from theory but need to be inferred from data. …”
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“…The FCN model  stems  from fuzzy cognitive maps and uses the notion of “concepts” and their causal relationships to capture the behavior of complex systems. The book shows how, with the benefit of proper training algorithms, these models are potent system emulators suitable for use in engineering systems.  …”
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“…The need for intelligent, flexible behaviour by large, complex systems, especially in mission-critical domains, is intended to be the catalyst and the aggregation stimulus for the overall event. …”
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“…This monograph aims to lay the groundwork for the design of a unified mathematical approach to the modeling and analysis of large, complex systems composed of interacting living things. …”
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“…In particular, triangulated manifolds play an important role in settings such as Riemann moduli space theory, strings and quantum gravity, topological quantum field theory, condensed matter physics, critical phenomena and complex systems. Not only do they provide a natural discrete analogue to the smooth manifolds on which physical theories are typically formulated, but their appearance is also often a consequence of an underlying structure that naturally calls into play non-trivial aspects of representation theory, complex analysis and topology in a way that makes the basic geometric structures of the physical interactions involved clear. …”
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“…Concerned governments, institutions, and actors concerned with addressing these issues must wrestle with complex systems that span time, space, and scale. This complexity of connected systems requires the participation of multiple actors across political boundaries, problem areas, and hydrologic domains. …”
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“…Higher-order networks have emerged as a powerful framework to model complex systems and their collective behavior. Going beyond pairwise interactions, they encode structured relations among arbitrary numbers of units through representations such as simplicial complexes and hypergraphs. …”
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“…CONCEPT: MNDO-based semi-empirical methods in quantum chemistry have found widespread application in the modelling of large and complex systems. A method for the analytic evaluation of first and second derivatives of molecular properties against semi-empirical parameters in MNDO-based NDDO-descendant models is presented, and the resultant parameter Hessian is compared against the approximant currently used in parameterization for the PMx models. …”
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“…International trade networks are complex systems that consist of overlapping multiple trade blocs of varying sizes. …”
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“…Finding such a reduced representation for complex systems is, however, a difficult task. We address this problem for dynamics on weighted directed networks, with special emphasis on modular and heterogeneous networks. …”
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“…Thanks to the rapid development of computer science and advances in high-performance computing (HPC) infrastructures, theoretical/computational chemistry has now matured enough to successfully and gainfully apply to tackle the challenges of complex systems. In mineral processing, however, advanced applications of computational chemistry are increasingly gaining ground and demonstrating merit in addressing these challenges. …”
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“…Although stochastic thermodynamics underpins the irreversible dynamics of small systems, the nonequilibrium thermodynamics of larger, more complex systems remains unexplored. Here, we investigate the asymmetric Sherrington-Kirkpatrick model with synchronous and asynchronous updates as a prototypical example of large-scale nonequilibrium processes. …”
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“…The brain is a complex system whose understanding enables potentially deeper approaches to mental phenomena. …”
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“…Neuronal networks are complex systems of interconnected neurons responsible for transmitting and processing information throughout the nervous system. …”
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