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  1. 2741
    “…Therefore, there is a need to utilize more complex systems to study the cHL-TME and its interplay with tumor cells. …”
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    Current and Emerging Approaches to Study Microenvironmental Interactions and Drug Activity in Classical Hodgkin Lymphoma
  2. 2742
    “…The RMSD and MM/PBSA methods of molecular dynamics simulations were also used to confirm the stable nature of this series of complex systems, and the weak protein–ligand interactions during the dynamics were graphically evaluated and further investigated. …”
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    Design of Rational JAK3 Inhibitors Based on the Parent Core Structure of 1,7-Dihydro-Dipyrrolo [2,3-b:3′,2′-e] Pyridine
  3. 2743
    “…We review the historical literature on respiratory pandemics and their documented connections to urban planning and design (both broadly defined as being concerned with cities as complex systems). Our systematic search across multidisciplinary databases returned a total of 1323 sources, with 92 articles included in the final review. …”
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    Respiratory pandemics, urban planning and design: A multidisciplinary rapid review of the literature
  4. 2744
    “…Broadband mid-infrared (MIR) spectroscopy is a well-established and valuable diagnostic technique for reactive plasmas. Plasmas are complex systems and consist of numerous (reactive) types of molecules; it is challenging to measure and control reaction specificity with a good sensitivity. …”
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    Mid-infrared supercontinuum-based Fourier transform spectroscopy for plasma analysis
  5. 2745
    por Chakwizira, James
    Publicado 2022
    “…Drawing from the complex systems adaptive theory (CSAT), sustainability theory (ST), innovation theory (IT), transitions theory (TT), thematic COVID -19 transport planning and policy adaptation, mitigation measures in the South African transportation sector are discussed. …”
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    Stretching resilience and adaptive transport systems capacity in South Africa: Imperfect or perfect attempts at closing COVID -19 policy and planning emergent gaps
  6. 2746
    “…The VIKOR technique was developed for multicriteria optimization of complex systems. RESULTS: After reviewing and extracting the criteria from various studies, 9 main criteria and 44 subcriteria were defined to select water resources in disasters and emergencies. …”
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    Alternative Water Resources Selection to Supply Drinking Water in Flood Disasters by Multicriteria Decision-Making Techniques (DANP and VIKOR)
  7. 2747
    por Valera, Sergi, Casakin, Hernan
    Publicado 2022
    “…Compared to more classical approaches and systems, these techniques allowed to identify and interpret complex systems composed of many variables and relationships in a relatively straightforward manner, which turns it into a useful aid for urban designers and architects.…”
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    Integrating Observation and Network Analysis to Identify Patterns of Use in the Public Space: A Gender Perspective
  8. 2748
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    High-performance computing and computational intelligence applications with a multi-chaos perspective
  9. 2749
    “…Combining UHPLC-IM-MS and UHPLC-Q-TOF MS can obtain not only more fragments but also their unique drift times and RT, which is more conducive to the identification of complex systems, especially isomers. This proposed strategy can provide an effective method to separate and identify chemical components, and distinguish isomers in the complex system of traditional Chinese medicine (TCM).…”
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    A Strategy for Identification and Structural Characterization of Compounds from Plantago asiatica L. by Liquid Chromatography-Mass Spectrometry Combined with Ion Mobility Spectrometry
  10. 2750
    “…Methods: We developed a theory-based co-production process and used a mixed methods approach to engage with policy- and decision-makers from across the United Kingdom in a series of 4 workshops, to better understand and respond to the complex systems in which they act. The first and fourth workshops (London) aimed to better understand the public health policy agenda and effective methods for co-production, communication and dissemination. …”
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    The QUEST for Effective and Equitable Policies to Prevent Non-communicable Diseases: Co-Production Lessons From Stakeholder Workshops
  11. 2751
    “…The Principle of Maximal Entropy Production (MEP) states that: If a source of free energy is present, complex systems can intercept the free energy flow, and self-organize to enhance entropy production. …”
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    Biology: Motion is Function
  12. 2752
    “…Radiocarbon ([Formula: see text]) is playing a crucial role in this scenario because it is one of the so-called difficult to measure isotopes; currently, [Formula: see text] analysis requires complex systems, such as accelerator mass spectrometry (AMS) or liquid scintillation counting (LSC). …”
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    Precise radiocarbon determination in radioactive waste by a laser-based spectroscopic technique
  13. 2753
    “…Researchers must find new ways of integrating socio-environmental costs at numerous key leverage points across multiple complex systems. This mixed-methods study comprises of six highly integrated work packages. …”
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    Tackling Root Causes Upstream of Unhealthy Urban Development (TRUUD): Protocol of a five-year prevention research consortium
  14. 2754
    “…It has been observed that the introduction of DNA/RNA nucleobases molecules alters the electronic properties of both oxygen and sulfur atomic layers of the Janus MoOS complex systems as determined by plotting the 3D Kohn–Sham frontier orbitals. …”
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    A Peculiar Binding Characterization of DNA (RNA) Nucleobases at MoOS-Based Janus Biosensor: Dissimilar Facets Role on Selectivity and Sensitivity
  15. 2755
    por Qian, Shaodi, Chou, Chun-An, Li, Jr-Shin
    Publicado 2022
    “…The underlying dynamics (or evolution rule) of such complex systems, if found, can be used for understanding the system behavior, and furthermore for system prediction and control. …”
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    Deep multi-modal learning for joint linear representation of nonlinear dynamical systems
  16. 2756
    “…This research not only provided new ideas for exploring the mechanism of complex systems such as Chinese herbals but also benefited the treatment strategy of Gastric Precancerous Lesions via regulating energy metabolism.…”
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    Proteomics and Metabolomics Unveil Codonopsis pilosula (Franch.) Nannf. Ameliorates Gastric Precancerous Lesions via Regulating Energy Metabolism
  17. 2757
    “…DPD behaved as a powerful tool for studying complex systems and shedding some light on some experimental observations, otherwise difficult to explain.…”
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    Nucleation and growth of gold nanoparticles in the presence of different surfactants. A dissipative particle dynamics study
  18. 2758
    “…Single-cell RNA-seq (scRNA-seq) is a powerful genomics technology to interrogate the cellular composition and behaviors of complex systems. While the number of scRNA-seq datasets and available computational analysis tools have grown exponentially, there are limited systematic data sharing strategies to allow rapid exploration and re-analysis of single-cell datasets, particularly in the cardiovascular field. …”
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    PlaqView 2.0: A comprehensive web portal for cardiovascular single-cell genomics
  19. 2759
    “…In reduced-order modeling, complex systems that exhibit high state-space dimensionality are described and evolved using a small number of parameters. …”
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    Cost function for low-dimensional manifold topology assessment
  20. 2760
    “…Network models (NMs) —a graph theory-based approach allowing us to describe the structure of complex systems— can provide a priori free insight into EFs structures. …”
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    A network analysis of executive functions before and after computerized cognitive training in children and adolescents
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