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2821por Pernice, Simone, Pennisi, Marzio, Romano, Greta, Maglione, Alessandro, Cutrupi, Santina, Pappalardo, Francesco, Balbo, Gianfranco, Beccuti, Marco, Cordero, Francesca, Calogero, Raffaele A.“…RESULTS: In this paper we propose a new methodology for studying RRMS, which we implemented in GreatSPN, a state-of-the-art open-source suite for modelling and analyzing complex systems through the Petri Net (PN) formalism. …”
Publicado 2019
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2822por Sawyer, Joseph M, Sallnow, Libby, Kupeli, Nuriye, Stone, Patrick, Sampson, Elizabeth L“…CONCLUSION: This review contributes to the dispassionate understanding of how complex systems such as community and social capital might be viewed as a tool to improve end-of-life care for people with dementia. …”
Publicado 2019
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2823“…We use the framework on integration of innovations in complex systems developed by Atun and others. We used qualitative approaches to study the implementation. …”
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2824“…More broadly, we demonstrate the conceptual value of marrying artificial systems with biological characterization, moving beyond “black box” reproduction of an architecture to advance understanding of complex systems, such as the brain. SIGNIFICANCE STATEMENT Using an artificial systems approach, we show that physiological properties of motion can result from natural image structure. …”
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2825“…The results disclosed herein lay the foundation for a clear interpretation of complex systems during the increasingly popular in situ NMR characterization at elevated temperatures and pressures for studying chemical systems.…”
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2826por Braithwaite, Jeffrey, Ludlow, Kristiana, Testa, Luke, Herkes, Jessica, Augustsson, Hanna, Lamprell, Gina, McPherson, Elise, Zurynski, Yvonne“…INTRODUCTION: The sustainability of healthcare delivery systems is challenged by ageing populations, complex systems, increasing rates of chronic disease, increasing costs associated with new medical technologies and growing expectations by healthcare consumers. …”
Publicado 2020
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2827por Ma, Bin, Wang, Yiling, Ye, Shudi, Liu, Shan, Stirling, Erinne, Gilbert, Jack A., Faust, Karoline, Knight, Rob, Jansson, Janet K., Cardona, Cesar, Röttjers, Lisa, Xu, Jianming“…BACKGROUND: Microbial interactions shape the structure and function of microbial communities; microbial co-occurrence networks in specific environments have been widely developed to explore these complex systems, but their interconnection pattern across microbiomes in various environments at the global scale remains unexplored. …”
Publicado 2020
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2828por Rangachari, Pavani“…The selected works used the theory of “effective knowledge sharing network structures in professional complex systems (PCS),” developed through an integration of organizational theories, to design prospective interventions for enabling EBP implementation in HCOs. …”
Publicado 2020
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2829por Kim, Kyoungnam, Ryu, Kitae, Cho, Hana, Shim, Min Suk, Cho, Yong-Yeon, Lee, Joo Young, Lee, Hye Suk, Kang, Han Chang“…In conclusion, a decomplexation rate controller could be a potential factor to establish a high TE and design clinically available gene complex systems.…”
Publicado 2020
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2830“…Network science provides effective tools to model and analyze complex systems. However, the increasing size of real-world networks becomes a major hurdle in order to understand their structure and topological features. …”
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2831por Morselli Gysi, Deisy, de Miranda Fragoso, Tiago, Zebardast, Fatemeh, Bertoli, Wesley, Busskamp, Volker, Almaas, Eivind, Nowick, Katja“…Biological and medical sciences are increasingly acknowledging the significance of gene co-expression-networks for investigating complex-systems, phenotypes or diseases. Typically, complex phenotypes are investigated under varying conditions. …”
Publicado 2020
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2832por Gu, Yanqiu, Chen, Xiao, Wang, Yao, Liu, Yue, Zheng, Leyi, Li, Xiaoqun, Wang, Rong, Wang, Shaozhan, Li, Shengnan, Chai, Yifeng, Su, Jiacan, Yuan, Yongfang, Chen, Xiaofei“…It can realize a dynamical simulation of interactions between drugs and receptors on cell membrane, which is suitable for screening active compounds from complex systems. In this study, the components of Scutellariae Radix with potential anti-osteoporosis activity through inhibiting the differentiation from bone marrow mononuclear cells (BMMCs) to osteoclast were screened by a BMMC/CMC analytical system. …”
Publicado 2020
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2833“…The revised framework consists of 11+1 criteria, supported by 48 aspects, and embraces a complex systems perspective. The criteria cover implications for the health of individuals and populations due to and beyond COVID-19, infringement on liberties and fundamental human rights, acceptability and equity considerations, societal, environmental and economic implications, as well as implementation, resource and feasibility considerations. …”
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2834por Verma, Rahul K., Kalyakulina, Alena, Giuliani, Cristina, Shinde, Pramod, Kachhvah, Ajay Deep, Ivanchenko, Mikhail, Jalan, Sarika“…Networks have been established as an extremely powerful framework to understand and predict the behavior of many large-scale complex systems. We studied network motifs, the basic structural elements of networks, to describe the possible role of co-occurrence of genomic variations behind high altitude adaptation in the Asian human population. …”
Publicado 2021
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2835por Evans, Rhiannon, Boffey, Maria, MacDonald, Sarah, Noyes, Jane, Melendez-Torres, G.J., Morgan, Helen E, Trubey, Rob, Robling, Michael, Willis, Simone, Wooders, Charlotte“…The present systematic review will adopt a complex systems perspective to synthesise evidence reporting evaluations of mental health and well-being interventions for care-experienced children and young people. …”
Publicado 2021
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2836“…At the other end, we contend that scale-up can sit within a complex systems paradigm in which interventions are conceptualised as events in systems. …”
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2837por Horton, Marie, Perman-Howe, Parvati R., Angus, Colin, Bishop, Julie, Bogdanovica, Ilze, Brennan, Alan, Britton, John, Brose, Leonie S., Brown, Jamie, Collin, Jeff, Dockrell, Martin, Fitzgerald, Niamh, Friel, Sharon, Gillespie, Duncan, Gilmore, Anna B., Hill, Sarah E., Knai, Cecile, Langley, Tessa, Martin, Sancha, McNeill, Ann, Moore, Graham, Munafò, Marcus R., Murray, Rachael L., Opazo Breton, Magdelena, Pearce, Jamie, Petticrew, Mark, Reid, Garth, Robson, Deborah, Rutter, Harry, Shahab, Lion, Shortt, Niamh, Smith, Katherine, Syrett, Keith, Bauld, Linda“…Through eight integrated work packages, the Consortium seeks to provide an understanding of the nature of the complex systems underlying the consumption of unhealthy commodities, the role of UCPs in shaping these systems and influencing health and policy, the role of systems-level interventions, and the effectiveness of existing and emerging policies. …”
Publicado 2021
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2838por Sazal, Musfiqur, Stebliankin, Vitalii, Mathee, Kalai, Yoo, Changwon, Narasimhan, Giri“…Association patterns can be coincidental and may lead to wrong conclusions about causality in complex systems. Microbiomes are highly complex, diverse, and dynamic environments. …”
Publicado 2021
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2839“…A key challenge to gaining insight into complex systems is inferring nonlinear causal directional relations from observational time-series data. …”
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2840“…Given its enhanced ability to understand the feature-interdependencies present in complex systems, this lookahead variation is a useful extension to the toolkit of data scientists, in particular for financial machine learning, where conditions (a) and (b) are typically met.…”
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