“…CONCLUSIONS: Replicating these types of organisational structures, processes, and culture requires consideration of complex systems perspectives on implementation fidelity which has implications for policy, practice and future research.…”
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“…Only recently have methods been developed that allow for studying such complex systems. Using the Rank-based Random Forest (RF) model, we show that PUFA metabolism genes are critical for the pathogenesis of breast cancer (BC); BC subtypes differ in PUFA metabolism gene expression. …”
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“…Due to the ambiguity and uncertainty of the risk assessment process, a multi-criteria decision-making technique for dealing with complex systems that involves choosing one of many options is an important strategy of assessing road safety. …”
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“…In the last decade, it has been applied to psychometric data in the attempt to explain psychopathologies as complex systems of causally interconnected symptoms. One category of mental disorders, relevant for their severity, incidence and multifaceted structure, is that of eating disorders (EDs), serious disturbances that negatively affect a person’s eating behavior. …”
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“…Complex networks have been used to model numerous complex systems due to its characteristics, including time series prediction and image classification. …”
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“…The analysis of both cell migration and invasiveness in vitro require more complex systems based on the Boyden chamber principle (Transwell migration/invasive test, xCELLigence system), or microfluidic devices with three-dimensional (3D) microscopy visualization. 3D culture techniques are rapidly becoming routine and involve multicellular spheroid invasion assays or array chip-based, spherical approaches, multi-layer/multi-zone culture, or organoid non-spherical models, including multi-organ microfluidic chips. …”
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“…Results show that the ternary systems Li(+),Rb(+)//SO(4)(2–)–H(2)O and Li(+),Cs(+)//SO(4)(2–)–H(2)O are both complex systems with two kinds of double salts formed at 273.2 K. …”
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“…These tools enable the possibility of interoperability, enabling the representation of more complex systems, inference capabilities, and the synthesis of new knowledge. …”
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“…Thus, the paper illustrates our experience of using PNS as an approach to science policy interfaces in a strategic policy context; and illustrates how the challenges identified in the science–policy literature are amplified when working across multiple policy domains and taking a complex systems approach. Our discussion on lessons learnt may be of interest to researchers seeking to work with policy-makers on complex sustainability issues.…”
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“…[Image: see text] Progress in the design of functional perovskite oxides relies on advances in density functional theory (DFT) methods to efficiently and effectively model complex systems composed of several transition-metal ions. …”
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“…BACKGROUND: Variation in omics data due to intrinsic biological stochasticity is often viewed as a challenging and undesirable feature of complex systems analyses. In fact, numerous statistical methods are utilized to minimize the variation among biological replicates. …”
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“…BASED ON THE PREMISES OF COMPLEX SYSTEMS, INTERDISCIPLINARITY AND SYSTEMS THEORY, THE INTERPRETATIONS THAT HAVE BEEN USED IN CATALOGUING IN ORDER TO SIGNIFY THINGS OF THE REAL AND VIRTUAL WORLDS WHICH LIVE TOGETHER IN THE BIBLIOGRAPHICAL UNIVERSE, ARE CONTRASTED. …”
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“…The three-dimensional integration on ultralow-loss photonic integrated circuits thus marks a critical step towards complex systems and networks on silicon.…”
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“…We extend our investigation in more complex systems characterized by activation of multiple inflammasomes such as the SOD1(G93A) mouse model. …”
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“…Moreover, in modelling complex systems, a complete annotation of all the components is equally important to understand the interaction mechanism inside the network: for this reason data integration of the model components has high relevance in systems biology studies. …”
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“…Random matrix theory (RMT), which has been widely and successfully used in physics, is a powerful approach to distinguish system-specific, non-random properties embedded in complex systems from random noise. Here, we have hypothesized that the universal predictions of RMT are also applicable to biological systems and the correlation threshold can be determined by characterizing the correlation matrix of microarray profiles using random matrix theory. …”
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“…Escherichia coli utilises a single sensory pathway, but little is known about signalling pathways in species with more complex systems. RESULTS: To investigate whether chemotaxis pathways in other bacteria follow the E. coli paradigm, we analysed 206 species encoding at least 1 homologue of each of the 5 core chemotaxis proteins (CheA, CheB, CheR, CheW and CheY). 61 species encode more than one of all of these 5 proteins, suggesting they have multiple chemotaxis pathways. …”
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“…BACKGROUND: Sensitivity analysis is an indispensable tool for the analysis of complex systems. In a recent paper, we have introduced a thermodynamically consistent variance-based sensitivity analysis approach for studying the robustness and fragility properties of biochemical reaction systems under uncertainty in the standard chemical potentials of the activated complexes of the reactions and the standard chemical potentials of the molecular species. …”
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“…To systematically probe the complete tracer design space, especially for complex systems such as mammalian cells, there is a pressing need for new rational approaches to identify optimal tracers. …”
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“…We hypothesized that COP metrics derived from complex systems theory may better capture the multi-component stimulus that Tai Chi has on the postural control system, as compared with traditional COP measures. …”
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