“…If one fathoms how simple early life must have been, the complexity of modern-day life is staggering by comparison. A minimally complex system that could plausibly provide pyrophosphates for early life could be the oxidation of reduced phosphorus sources such as hypophosphite and phosphite. …”
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“…Here, we consider those cytokines, chemokines, and MDSCs as an intricately connected, complex system and we focus on how tumors manipulate the MDSCs through various cytokines and chemokines. …”
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“…One of the emergent methods for the study of functional connectivity in electrophysiological recordings is graph theory: it allows to describe the brain through a mathematic model, the graph, and provides a simple representation of a complex system. As Alzheimer’s and Parkinson’s disease are associated with synaptic disruptions and changes in the strength of functional connectivity, they can be well described by functional connectivity analysis computed via graph theory. …”
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“…The rapid development of microsystems technology with the availability of various machine learning algorithms facilitates human activity recognition (HAR) and localization by low-cost and low-complexity systems in various applications related to industry 4.0, healthcare, ambient assisted living as well as tracking and navigation tasks. …”
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“…Even though brain is a super-complex system with 10(11) neurons, its intelligence does depend rather on the neuronal type and their energy supply mode than the number of neurons. …”
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“…Deformation of crystalline materials is an interesting example of complex system behaviour. Small samples typically exhibit a stochastic-like, irregular response to externally applied stresses, manifested as significant sample-to-sample variation in their mechanical properties. …”
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“…It was found that an appropriate concentration of CdTe QDs could enhance the performance of multi-PCR by reducing the formation of nonspecific products in the complex system, but an excessive amount of CdTe QDs could suppress the PCR. …”
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“…This paper discusses the creation of an Agent-Based Simulation that modeled the introduction of care coordination capabilities into a complex system of care for patients with Serious and Persistent Mental Illness. …”
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“…In a complex system, perturbations propagate by following paths on the network of interactions among the system’s units. …”
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“…We found that seeing gestures representing actions enhanced understanding of the dynamics of a complex system as revealed in invented language, gestures and visual explanations. …”
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“…Our holistic approach can help managers identify looming problems arising from complex system interactions and prioritise among problems and solutions, even when available data are limited. …”
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“…The cardiac conduction system (CCS) encompasses a complex system responsible for the coordinated contraction of the heart. …”
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“…These mol­ecules are connected via a complex system of hydrogen bonds into an infinite assembly along the [100] axis; hydro­phobic tert-butyl and phenyl groups form an external coating of the assembly. …”
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“…The hypothalamic-pituitary-adrenal axis is a complex system of neuroendocrine pathways and feedback loops that function to maintain physiological homeostasis. …”
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“…DEMATEL method is based on graph theory which takes the global information into full consideration so that it can effectively identify the importance of one element in the whole complex system. Some experiments based on susceptible-infected (SI) model are used to compare the new model with other methods. …”
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“…In this perspective, we reflect upon the question: what processes may help transition scientific insights on sustainability issues into practice and thus contribute to tackling the complex, systemic sustainability problems of today? We use five forerunners in the field of providing and brokering knowledge for science informed real world solutions, all published in Ambio and highlighted in this Anniversary collection, as our starting point. …”
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“…Simulation is a key tool for researching complex system behaviour. Agent-based simulation has been applied across domains, such as biology, health, economics and urban sciences. …”
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“…The resistance against leaf spot diseases caused by each individual necrotroph/hemi-biotroph involves a complex system involving resistance (R) genes, sensitivity (S) genes, small secreted protein (SSP) genes and quantitative resistance loci (QRLs). …”
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“…The aim of present investigation was 1) to evaluate the in vivo bioavailability of an Etodolac (ETD)-β-cyclodextrin (β-CD) inclusion complex system prepared by kneading and spray drying techniques in rats, 2) to study the pharmacodynamic parameters in various animal models for analyzing the therapeutic response and, 3) to evaluate the pharmacokinetic profile of the drug administered. …”
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“…Upon the identification of anandamide (AEA) in the porcine brain, numerous studies contributed to the current state of knowledge regarding all elements that form the “endocannabinoid system (ECS).”How this complex system of receptors, ligands, and enzymes is integrated in helping to regulate fundamental processes at level of central nervous and peripheral systems and how its regulation and dysregulation might counteract disturbances of such functions, is nowadays still under investigation. …”
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