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3241por Pais-Vieira, Miguel, Lebedev, Mikhail, Kunicki, Carolina, Wang, Jing, Nicolelis, Miguel A. L.“…These results demonstrated that a complex system was formed by coupling the animals' brains, suggesting that BTBIs can enable dyads or networks of animal's brains to exchange, process, and store information and, hence, serve as the basis for studies of novel types of social interaction and for biological computing devices.…”
Publicado 2013
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3242“…The precise regulation of gene transcription during metazoan development is controlled by a complex system of interactions between transcription factors, histone modifications and modifying enzymes and chromatin conformation. …”
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3243por Corada, Monica, Orsenigo, Fabrizio, Morini, Marco Francesco, Pitulescu, Mara Elena, Bhat, Ganesh, Nyqvist, Daniel, Breviario, Ferruccio, Conti, Valentina, Briot, Anais, Iruela-Arispe, M. Luisa, Adams, Ralf H., Dejana, Elisabetta“…The functional diversity of the arterial and venous endothelia is regulated through a complex system of signalling pathways and downstream transcription factors. …”
Publicado 2013
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3244por Gao, Zhong-Ke, Yang, Yu-Xuan, Zhai, Lu-Sheng, Dang, Wei-Dong, Yu, Jia-Liang, Jin, Ning-De“…High water cut and low velocity vertical upward oil-water two-phase flow is a typical complex system with the features of multiscale, unstable and non-homogenous. …”
Publicado 2016
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3245por Walker, Sara I., Bains, William, Cronin, Leroy, DasSarma, Shiladitya, Danielache, Sebastian, Domagal-Goldman, Shawn, Kacar, Betul, Kiang, Nancy Y., Lenardic, Adrian, Reinhard, Christopher T., Moore, William, Schwieterman, Edward W., Shkolnik, Evgenya L., Smith, Harrison B.“…We describe empirical and theoretical work necessary to place constraints on the relevant likelihoods, including those emerging from better understanding stellar environment, planetary climate and geophysics, geochemical cycling, the universalities of physics and chemistry, the contingencies of evolutionary history, the properties of life as an emergent complex system, and the mechanisms driving the emergence of life. …”
Publicado 2018
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3246“…This paper conducts a study of the tensor model for nonlinear equations and it includes the following: (i) a three dimensional symmetric tensor trust-region subproblem model of the nonlinear equations is presented; (ii) the three dimensional symmetric tensor is replaced by interpolating function and gradient values from the most recent past iterate, which avoids the storage of the three dimensional symmetric tensor and decreases the workload of the computer; (iii) the limited BFGS quasi-Newton update is used instead of the second Jacobian matrix, which generates an inexpensive computation of a complex system; (iv) the global convergence is proved under suitable conditions. …”
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3247“…Tumor microenvironment is a complex system that contains multiple cells and cytokines. …”
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3248“…With around 100 deubiquitinating enzymes and 600 ubiquitin ligases in the human genome targeting a subclass of these enzymes or even a single enzyme is a compelling strategy to unpick this complex system. In this review we will discuss different approaches adopted, including activity-based probes centered around ubiquitin-protein, ubiquitin-peptide and mutated ubiquitin scaffolds. …”
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3249por Weiss, Jonathan R., Qiu, Qiang, Barbot, Sylvain, Wright, Tim J., Foster, James H., Saunders, Alexander, Brooks, Benjamin A., Bevis, Michael, Kendrick, Eric, Ericksen, Todd L., Avery, Jonathan, Smalley, Robert, Cimbaro, Sergio R., Lenzano, Luis E., Barón, Jorge, Báez, Juan Carlos, Echalar, Arturo“…Deformation associated with plate convergence at subduction zones is accommodated by a complex system involving fault slip and viscoelastic flow. …”
Publicado 2019
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3250por Sinagra, Emanuele, Utzeri, Erika, Morreale, Gaetano Cristian, Fabbri, Carlo, Pace, Fabio, Anderloni, Andrea“…The aim of this narrative review is to elaborate on the concept of the gut-brain-microbiota axis and its clinical significance regarding IBD on the basis of recent scientific literature, and finally to focus on pharmacological therapies that could allow us to favorably modify the function of this complex system.…”
Publicado 2020
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3251“…In order to simulate this complex system, we construct an ab initio quality interaction potential by training a neural network on a set of density functional theory calculations performed on configurations generated in multithermal–multibaric simulations. …”
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3252por Claxton, Benjamin B., Dimmock, Anne E.F., Jain, Rohit, Drummond, M. Bradley, Bascom, Rebecca“…Effective treatments for human herpes virus 8 (HHV-8) associated multicentric Castleman disease (MCD) have led to prolonged survival for this complex systemic lymphoproliferative inflammatory disease. …”
Publicado 2020
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3253por Li, Xiao‐jin, You, Xin‐yu, Wang, Cong‐ying, Li, Xue‐li, Sheng, Yuan‐yuan, Zhuang, Peng‐wei, Zhang, Yan‐jun“…The brain‐gut‐microbiota axis is a complex system that plays a crucial role in the occurrence and development of central nervous system diseases. …”
Publicado 2020
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3254“…It aims to predict missing (or future) links between two entities in a complex system that are not already connected. Among existing methods, local similarity indices are most popular that take into account the information of common neighbours to estimate the likelihood of existence of a connection between two nodes. …”
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3255por Tirrò, Elena, Massimino, Michele, Romano, Chiara, Martorana, Federica, Pennisi, Maria Stella, Stella, Stefania, Pavone, Giuliana, Di Gregorio, Sandra, Puma, Adriana, Tomarchio, Cristina, Vitale, Silvia Rita, Manzella, Livia, Vigneri, Paolo“…Insulin-like growth factor (IGF) signaling entails a complex system that is a key regulator of cell transformation, growth and cell-cycle progression. …”
Publicado 2021
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3256por Orlova, Yuliia, Gambardella, Alessa A., Kryven, Ivan, Keune, Katrien, Iedema, Piet D.“…[Image: see text] The autoxidation of triglyceride (or triacylglycerol, TAG) is a poorly understood complex system. It is known from mass spectrometry measurements that, although initiated by a single molecule, this system involves an abundance of intermediate species and a complex network of reactions. …”
Publicado 2021
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3257por Rajasekaran, Arun, Franco, Ricardo A., Overton, Edgar T., McGuire, Brendan M., Towns, Graham C., Locke, Jayme E., Sawinski, Deirdre L., Bell, Emmy K.“…Obstacles to eliminate HCV in HD settings remain daunting due to a complex system created by a confluence of guidelines, legislation, regulation, and economics. …”
Publicado 2021
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3258por Dey, Pankaj“…In this paper, a complex system-based measure – burstiness – is used to quantify the variability of interevent times across six meteorologically homogenous zones of India. …”
Publicado 2023
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3259por Shiers, J“…This is a highly complex system with many components but which must provide a robust and resilient service. …”
Publicado 2007
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3260por Strässner, A“…An overview about the various components necessary to develop such a complex system will be given. The current R&D activities and architectural studies of the LAr Calorimeter group will be presented, in particular the on-going design of the mixed-signal and radiation hard front-end ASICs, the Silicon-on-Saphire (SOS) based optical-link, the high-speed off-detector FPGA based processing units and the power supply distribution scheme.…”
Publicado 2009
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