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  1. 3341
    “…The simulations provide new insights into the complex system of DNA replication, showing that the system is robust to perturbation, and giving hints about the influence of a possible disordered firing. …”
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    A model for the spatiotemporal organization of DNA replication in Saccharomyces cerevisiae
  2. 3342
    “…Optimization of such a complex system requires strategies that efficiently discover solutions in extremely large volumes of potential experimental space. …”
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    Automated Discovery of Novel Drug Formulations Using Predictive Iterated High Throughput Experimentation
  3. 3343
    por Jin, Ping, Wang, Ena
    Publicado 2003
    “…Far from pontificating on this obvious point, this review presents emerging evidence that the study of complex system such as the cytokine network is further complicated by inter-individual differences dictated by increasingly recognized polymorphisms. …”
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    Polymorphism in clinical immunology – From HLA typing to immunogenetic profiling
  4. 3344
    por McLendon, Roger E., Rich, Jeremy N.
    Publicado 2011
    “…To neuropathologists, glioblastoma is a tumor that represents a complex system of migrating pleomorphic tumor cells, proliferating blood vessels, infiltrating inflammatory cells, and necrosis. …”
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    Glioblastoma Stem Cells: A Neuropathologist's View
  5. 3345
    “…In this paper, this complex system and function of the salivary defense proteins will be reviewed.…”
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    Salivary Defense Proteins: Their Network and Role in Innate and Acquired Oral Immunity
  6. 3346
    por Ibraguimov, A., Owens, L., Su, J., Tang, L.
    Publicado 2012
    “…There is an intensive research interest in the area of wound healing modeling, and quantitative methods are proposed to systematically study the behavior of this complex system of multiple cells, proteins, and enzymes. …”
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    Stability Analysis of a Model for Foreign Body Fibrotic Reactions
  7. 3347
    “…To help unravel these complexities, systems biology methods have been applied to develop an array of computational metabolic models, ranging from mitochondria-specific processes to genome-scale cellular networks. …”
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    Mechanistic modeling of aberrant energy metabolism in human disease
  8. 3348
    “…The setting is a cooperative, interacting complex system modelled as an Ising-Hopfield network in which the intensity of mutual interactions or “synapses” varies with time in such a way that it accounts for, e.g., a kind of fatigue reported to occur in the cortex. …”
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    Stochastic Resonance Crossovers in Complex Networks
  9. 3349
    por Sturm, Robert
    Publicado 2012
    “…The shape of the gland is characterized by a complex system of tubules, including numerous ramifications. …”
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    Morphology and Ultrastructure of the Accessory Glands in the Female Genital Tract of the House Cricket, Acheta domesticus
  10. 3350
    “…Consequently, in many studies, a protein structure was treated as a complex system comprised of individual components residues, and edges were interactions between residues. …”
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    The Effect of Edge Definition of Complex Networks on Protein Structure Identification
  11. 3351
    “…The eating disorders (DCA) are complex systemic diseases with high social impact, which tend to become chronic with significant medical and psychiatric comorbidities. …”
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    The Pharmacological Options in the Treatment of Eating Disorders
  12. 3352
    por Linder, Maria C.
    Publicado 2013
    “…In the face of uncertainties in iron bioavailability, the mammalian organism has evolved a complex system to retain and store iron not immediately in use, and to make that iron available when and where it is needed. …”
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    Mobilization of Stored Iron in Mammals: A Review
  13. 3353
    “…Here we provide an overview of the complex system of crosstalk between the neuroendocrine and immune system as well as reported dysfunctions involved in the pathogenesis of autoimmunity, including MS. …”
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    Neuroendocrine Immunoregulation in Multiple Sclerosis
  14. 3354
    “…Eukaryotic cells have evolved a complex system for protein synthesis regulation and this review will summarize cellular strategies to regulate mRNA translation upon stress and its impact on longevity.…”
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    Interrelation Between Protein Synthesis, Proteostasis and Life Span
  15. 3355
    “…So, no single assay could accurately reflect comparison in a mixed or complex system. Therefore in the present study the comparison of extracts was done by using most widely used assays viz. …”
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    Comparative analysis of antioxidant and phenolic content of chloroform extract/fraction of Terminalia chebula
  16. 3356
    “…So, no single assay could accurately reflect comparison in a mixed or complex system. Therefore in the present study the comparison of extracts was done by using most widely used assays viz. …”
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    Comparative analysis of antioxidant and phenolic content of chloroform extract/fraction of Terminalia chebula
  17. 3357
    por Bordoni, Bruno, Zanier, Emiliano
    Publicado 2014
    “…In our opinion, knowing and understanding this complex system of fascial layers is essential for the clinician and other health practitioners in finding the best treatment strategy for the patient.…”
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    Clinical and symptomatological reflections: the fascial system
  18. 3358
    por Xu, Dandan, Guo, Xulin
    Publicado 2015
    “…However, the grassland ecosystem is a complex system which is formed by soil, vegetation, wildlife and atmosphere. …”
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    Some Insights on Grassland Health Assessment Based on Remote Sensing
  19. 3359
    “…Genome wide association studies taking advantage of these large cohorts have identified several alleles from the major histocompatibility complex system indicating a fundamental role of the adaptive immune system in DILI pathogenesis. …”
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    Case Characterization, Clinical Features and Risk Factors in Drug-Induced Liver Injury
  20. 3360
    “…The neuroendocrine-immune (NEI) regulatory network is a complex system, which plays an indispensable role in the immunity of host. …”
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    The neuroendocrine immunomodulatory axis-like pathway mediated by circulating haemocytes in pacific oyster Crassostrea gigas
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