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  1. 3401
    por Gao, Xin, He, Jing, Sun, Xiaolin, Li, Fangting
    Publicado 2022
    “…Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease characterized by an overactive immune response to self-antigen. …”
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    Online Artículo Texto
    Dynamically modeling the effective range of IL-2 dosage in the treatment of systemic lupus erythematosus
  2. 3402
    por Santocchia, A, Albergo, S, Angarano, M, Azzi, P, Babucci, E, Bacchetta, N, Bader, A, Bagliesi, G, Bartalini, P, Basti, A, Biggeri, U, Bilei, G M, Bisello, D, Boemi, D, Da Rold, M, Bosi, F, Borrello, L, Bozzi, C, Breuker, H, Candelori, A, Caner, A, Dell'Orso, R, Castaldi, R, Carstro, A, Checcucci, B, Ciampolini, P, Creanza, D, Elliot-Peisert, A, de Palma, M, Della Marina, R, Bruzzi, M, Catacchini, E, Civinini, C, Connotte, J, Gu, W H, Luebelsmeyer, K, D'Alessandro, R, Pandoulas, D, Sielding, R, Wittmer, B, Fiore, L, Maggi, G, My, S, Raso, G, Selvaggi, Silvestris, Tempesta, P, Piperov, S, Tricomi, A, Potenza, R, French, M, Focardi, E, Meschini, M, Parrini, G, Pieri, M, Glessing, B, Hammerstrom, R, Huhtinen, M, Mannelli, M, Marchioro, A, Schmitt, B, Stefanini, G, Eklund, C, Karimäki, V, Skog, K, Tuuva, T, Hall, G, McEvoy, B, Ramond, M, Watts, S, Giraldo, A, Loreti, M, Martignon, G, Paccagnella, A, Stavitsky, I, Lariccia, P, Mantovani, G, Passeri, D, Servoli, L, Wang, Y, Giassi, A, Verdini, P G, Vannini, C, Tonelli, G, Xie, Z, Messineo, A, Palla, F, Raffaelli, F, Sguazzoni, G, Starodumov, A, Freudenreich, K, Lustermann, W, Viertel, G, Krammer, M, Hrubec, J
    Publicado 1998
    “…Lastly we describe the complex system prototypes which have been recently built to address the system aspects of such a large silicon tracker.…”
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    The CMS Silicon Tracker Detector: an Overview of the R&D Current Status
  3. 3403
    “…Hilbert spaces, which have been used in other disciplines, are considered to be an option to support the analysis and management of the watershed as a complex system.…”
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    Online Artículo
    Methodological proposal for the application of Hilbert spaces to integrated watershed management
  4. 3404
    “…The transition from bulk studies to single cell approaches brought significant insights by revealing complex system phenotypes, from the molecular to the organism level. …”
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    Online Artículo Texto
    Endogenous neural stem cells characterization using omics approaches: Current knowledge in health and disease
  5. 3405
    “…The brain is a complex system comprising a myriad of interacting elements, posing significant challenges in understanding its structure, function, and dynamics. …”
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    Online Artículo Texto
    Neuroscience needs Network Science
  6. 3406
    “…Ischemic stroke is a highly complex systemic disease characterized by intricate interactions between the brain and gastrointestinal tract. …”
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    Online Artículo Texto
    The gastrointestinal-brain-microbiota axis: a promising therapeutic target for ischemic stroke
  7. 3407
    “…In order to ensure the quality and applicability of these particles, various novel methods for characterizing the magnetic gold particles, including the analysis of their morphology, optical response, and magnetic response, are also discussed, with the overall goal of optimizing the fabrication of this complex system and thus enhancing its potential as a preferred diagnostic agent.…”
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    Online Artículo Texto
    Novel Characterization Techniques for Multifunctional Plasmonic–Magnetic Nanoparticles in Biomedical Applications
  8. 3408
    “…In addition, by taking advantage of a ‘hitchhiker' effect in which cells producing the ligand can induce chemotaxis of neighboring cells lacking enzymatic activity, we were able to design a more complex system that functions as a simple microbial consortium. …”
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    Engineered single- and multi-cell chemotaxis pathways in E. coli
  9. 3409
    “…It is clear that pathology is in part related to the pro-inflammatory nature of the host response but a number of other factors are also thought to be involved, including the interaction between infected erythrocytes and endothelium. This is a complex system involving several host receptors and a major parasite-derived variant antigen (PfEMP1) expressed on the surface of the infected erythrocyte membrane. …”
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    Specific Receptor Usage in Plasmodium falciparum Cytoadherence Is Associated with Disease Outcome
  10. 3410
    “…Our understanding of pancreatic ductal adenocarcinoma (PDAC) is shifting away from a disease of malignant ductal cells-only, toward a complex system where tumor evolution is a result of interaction of cancer cells with their microenvironment. …”
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    Online Artículo Texto
    How fibrosis influences imaging and surgical decisions in pancreatic cancer
  11. 3411
    “…The corticospinal (CS) tract is a complex system which targets several areas of the spinal cord. …”
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    Online Artículo Texto
    Sensorimotor Integration by Corticospinal System
  12. 3412
    “…However, quantitative identification of the interfacial undercooling in the solidification of colloidal suspensions, is still absent; thus, the question of which type of undercooling is dominant in this complex system remains unanswered. Here, we quantitatively measured the static and dynamic interface undercoolings of SCS and PCS in ideal and practical colloidal systems. …”
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    Interfacial undercooling in solidification of colloidal suspensions: analyses with quantitative measurements
  13. 3413
    “…Here, we apply experimental and theoretical methods to assess the ultrafast nonadiabatic vibronic processes in a prototypical complex system—the excited benzene cation. We use few-femtosecond duration extreme ultraviolet and visible/near-infrared laser pulses to prepare and probe excited cationic states and observe two relaxation timescales of 11 ± 3 fs and 110 ± 20 fs. …”
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    Online Artículo Texto
    Few-femtosecond passage of conical intersections in the benzene cation
  14. 3414
    “…With a highly nonlinear, complex system as the glucose homeostasis, the various provocations will contribute with different information offering a rich choice. …”
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    Online Artículo Texto
    Study Design Selection in Early Clinical Anti‐Hyperglycemic Drug Development: A Simulation Study of Glucose Tolerance Tests
  15. 3415
    por Lu, Haoyuan, Xu, Hao, Zhao, Jianye, Hou, Dong
    Publicado 2020
    “…In the development of a mode-locked deep ultraviolet laser, one of the most important aspects is to optimize the multiple parameters of the complex system. Traditional optimization methods require experimenters with more optimization experience, which limits the wide application of the lasers. …”
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    A Deep Ultraviolet Mode-locked Laser Based on a Neural Network
  16. 3416
    “…State monitoring of the complex system needs a large number of sensors. Especially, studies in soft electronics aim to attain complete measurement of the body, mapping various stimulations like temperature, electrophysiological signals, and mechanical strains. …”
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    A deep-learned skin sensor decoding the epicentral human motions
  17. 3417
    “…The plasma membrane is a complex system, consisting of two layers of lipids and proteins compartmentalized into small structures called nanodomains. …”
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    Online Artículo Texto
    Interleaflet Coupling of Lipid Nanodomains – Insights From in vitro Systems
  18. 3418
    “…However, inhibiting biofilm formation is difficult in that it is a complex system involving the physical and chemical interaction of both substrate and bacteria. …”
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    Thermodynamic Surface Analyses to Inform Biofilm Resistance
  19. 3419
    “…Here, we reveal new mechanisms that control human canal development and highlight for the first time the complex system of canal closure and reopening. These processes can be perturbed in mutant mice and in explant culture, mimicking the defects associated with canal atresia. …”
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    Epithelial dynamics shed light on the mechanisms underlying ear canal defects
  20. 3420
    “…The desmoplastic stroma is a complex system in which crosstalk takes place between cancer-associated fibroblasts, immune cells and cancer cells. …”
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    Online Artículo Texto
    Nerve Fibers in the Tumor Microenvironment Are Co-Localized with Lymphoid Aggregates in Pancreatic Cancer
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