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  1. 3541
    “…Slip velocity, axial gas dispersion, gas bypassing, and particle mixing phenomena have been evaluated under riser flow conditions to study the complex system behavior in detail. The most important factors are found to be directly related to particle cluster formation. …”
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    Computational Fluid Dynamics–Discrete Element Method (CFD-DEM) Study of Mass-Transfer Mechanisms in Riser Flow
  2. 3542
    “…Sarcoidosis is a complex systemic granulomatous disorder of unknown etiology. …”
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    RNA-sequencing Identifies Novel Pathways in Sarcoidosis Monocytes
  3. 3543
    “…Dogs can spontaneously develop complex systemic autoimmune disorders, with similarities to human autoimmune disease. …”
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    ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease
  4. 3544
    “…Although the significance of the complex system as an analytic lens is increasingly recognised, many researchers are still using methods that assume a closed system in which predictive studies in general, and controlled experiments in particular, are possible and preferred. …”
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    Studying complexity in health services research: desperately seeking an overdue paradigm shift
  5. 3545
    por Dabaghian, Yuri
    Publicado 2019
    “…Various neurophysiological and cognitive functions are based on transferring information between spiking neurons via a complex system of synaptic connections. In particular, the capacity of presynaptic inputs to influence the postsynaptic outputs–the efficacy of the synapses–plays a principal role in all aspects of hippocampal neurophysiology. …”
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    Through synapses to spatial memory maps via a topological model
  6. 3546
    por Celarain, Naiara, Tomas-Roig, Jordi
    Publicado 2020
    “…Epigenetics refers to a complex system that modifies gene expression without altering the DNA sequence. …”
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    Aberrant DNA methylation profile exacerbates inflammation and neurodegeneration in multiple sclerosis patients
  7. 3547
    “…BACKGROUND: The vacuolar protein sorting 35 (VPS35) is a major component of the retromer complex system, an ubiquitous multiprotein assembly responsible for sorting and trafficking protein cargos out of the endosomes. …”
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    A pharmacological chaperone improves memory by reducing Aβ and tau neuropathology in a mouse model with plaques and tangles
  8. 3548
    “…The brain is possibly the most complex system known to mankind, and its complexity has been called upon to explain the emergence of consciousness. …”
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    Consciousness & Brain Functional Complexity in Propofol Anaesthesia
  9. 3549
    “…In the corresponding theoretical model, we treated the proteins as limited-valence (patchy) particles and identified a wetting transition for this complex system. This wetting is driven by a bulk instability introduced by metastable LLPS exposed to an ion-activated attractive substrate.…”
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    Enhanced protein adsorption upon bulk phase separation
  10. 3550
    “…Globally, the variations found in the serum metabolome of COVID-19 patients may reflect a more complex systemic perturbation induced by SARS-CoV-2, possibly affecting carbon and nitrogen liver metabolism.…”
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    The Serum Metabolome of Moderate and Severe COVID-19 Patients Reflects Possible Liver Alterations Involving Carbon and Nitrogen Metabolism
  11. 3551
    “…We show that concepts and methods of complex system thinking now enable to fruitfully monitor and analyse the multiple interactions between symptoms in such in networks, offering new routes for prognosis and treatment. …”
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    Why illness is more important than disease in old age
  12. 3552
    “…These previously unknown findings indicate that the Terra Australis Orogen was not just a simple accretionary style orogen but rather a complex system with multiple tectonic styles operating in tandem including collisional tectonics.…”
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    Metamorphic diamond from the northeastern margin of Gondwana: Paradigm shifting implications for one of Earth’s largest orogens
  13. 3553
    “…Dynamic causal modelling is a form of complex system modelling, which uses ‘real world’ timeseries to estimate the parameters of an underlying state space model using variational Bayesian procedures. …”
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    Dynamic causal modelling of COVID-19 and its mitigations
  14. 3554
    “…Finally, we show that interactome hijacking by the viral PBM of human papillomavirus E6 oncoprotein substantially impacts the host cell proteome beyond immediate E6 binders, illustrating the complex system-wide relationship between interactome and function.…”
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    Quantitative fragmentomics allow affinity mapping of interactomes
  15. 3555
    “…SUMMARY: Embedding person-centred obesity care across the globe will require a complex system approach to provide a framework for healthcare system redesign, advances in people-driven discovery and advocacy for policy change. …”
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    Can We Deliver Person-Centred Obesity Care Across the Globe?
  16. 3556
    “…Up to now, there is no forthcoming method to extract any proteins from a complex system, and the field of protein purification still faces significant opportunities and challenges. …”
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    (1)Progress, applications, challenges and prospects of protein purification technology
  17. 3557
    por Sottocornola, Simone
    Publicado 2020
    “…Particular focus is given to the peculiar requirements that a complex system as FTK pose to the development of the online software infrastructure. …”
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    An Hardware based Tracker for the ATLAS Experiment: Commissioning and Trigger studies
  18. 3558
    “…We show that adapted RETFound consistently outperforms several comparison models in the diagnosis and prognosis of sight-threatening eye diseases, as well as incident prediction of complex systemic disorders such as heart failure and myocardial infarction with fewer labelled data. …”
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    A foundation model for generalizable disease detection from retinal images
  19. 3559
    “…Petri net (PN) is a mathematical and graphic tool used to simulate and study complex system processes. This article utilizes PN to study the relationship between norepinephrine and dopamine in depression. …”
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    Modeling and analyzing the action process of monoamine hormones in depression: a Petri nets-based intelligent approach
  20. 3560
    “…Despite the clear benefits of implementing circular economy principles, we identify many functional barriers impeding the structural reorganisation needed for such complex system change, and propose enablers to transform the forestry value-chain into an effective societal change system and lead to coherent action.…”
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    Circular wood use can accelerate global decarbonisation but requires cross-sectoral coordination
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