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3601“…The lung tumor microenvironment is a more complex system that further enhances the immunosuppressive features in the lungs. …”
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3602“…In many high complexity systems (cells, organisms, institutions, societies, economies, etc.), it is unclear which components should be regulated to affect overall performance. …”
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3603Publicado 1984“…We conclude that Na+ flux and its effect on intracellular K and pH has a major role in the complex system that regulates proliferation.…”
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3604por Milstone, J. H.“…Thus, the quantity of thrombokinase obtainable is compatible with a physiologic role. In the more complex system used for routine assay, thrombokinase can be supplied by crude plasma at a dilution of 1/500. …”
Publicado 1959
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3605“…We use mutual information that is widely used in communication and complex system analysis to measure gene-environment interactions. …”
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3606“…Cellular life is a highly redundant complex system; yet, the evolutionary maintenance of the redundancy remains unexplained. …”
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3607“…Their mutant phenotypes and distinct species-specific characteristics expose a surprisingly complex system of joint molecule processing. In an attempt to reconcile the biochemical and genetic data, we propose that nicked junctions constitute important in vivo recombination intermediates whose processing determines the efficiency and outcome (crossover/non-crossover) of homologous recombination.…”
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3608por Lee, Kyu-Min, Yang, Jae-Suk, Kim, Gunn, Lee, Jaesung, Goh, Kwang-Il, Kim, In-mook“…The global economic system is a highly complex system and can best be viewed in terms of a network of interacting macroeconomic agents. …”
Publicado 2011
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3609“…A basic-helix-loop-helix-zipper (bHLHZ) domain mediates the competitive protein dimerization and DNA binding among Max and Mlx network members to form a complex system of cell regulation. To understand the importance of these network interactions, we identified the bHLHZ domain of Max and Mlx network proteins across the animal kingdom and carried out several multivariate statistical analyses. …”
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3610“…First we show that scientific collaboration network is a complex system which evolves intensively at the local level – fewer than 20% of scientific collaborations last more than one year. …”
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3611“…Vitamin D system is a complex pathway that includes precursors, active metabolites, enzymes, and receptors. This complex system actives several molecular pathways and mediates a multitude of functions. …”
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3612“…Honey bee societies (Apis mellifera), the ectoparasitic mite Varroa destructor, and honey bee viruses that are vectored by the mite, form a complex system of host–parasite interactions. Coevolution by natural selection in this system has been hindered for European honey bee hosts since apicultural practices remove the mite and consequently the selective pressures required for such a process. …”
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3613por Parra-Guillen, Zinnia Patricia, Fioravanti, Jessica, Medina-Echeverz, Jose, Gomar, Celia, Ardaiz, Nuria, Troconiz, Iñaki F., Berraondo, Pedro“…Therefore, the modelling approach provided a global comprehension of a complex system and allowed us to compare the in vivo behaviour of both compounds and to identify critical aspects that might be important to understand the system better and suggests a need for new model-based experiments.…”
Publicado 2012
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3614“…However, there exists no algorithm-independent metric to characterize hierarchical modularity in a complex system. The main results of the paper are a set of methods to address this problem. …”
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3615“…The Earth, with its core-driven magnetic field, convective mantle, mobile lid tectonics, oceans of liquid water, dynamic climate and abundant life is arguably the most complex system in the known universe. This system has exhibited stability in the sense of, bar a number of notable exceptions, surface temperature remaining within the bounds required for liquid water and so a significant biosphere. …”
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3616“…Ameloblastomas are common, have an aggressive behavior and recurrent course, and are rarely metastatic, while AOTs are hamartomatous benign lesions derived from the complex system of the dental lamina or its remnants. With advances in the elucidation of molecular signaling mechanisms in cells, the cytodifferentiation of epithelial tumor cells in ameloblastomas and AOTs can be identified using different biomarkers. …”
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3617por Hruz, Tomas, Wyss, Markus, Lucas, Christoph, Laule, Oliver, von Rohr, Peter, Zimmermann, Philip, Bleuler, Stefan“…Visualization of large complex networks has become an indispensable part of systems biology, where organisms need to be considered as one complex system. The visualization of the corresponding network is challenging due to the size and density of edges. …”
Publicado 2013
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3618“…This is difficult, because whole-community data are limited and typically comprise only a snapshot of a community instead of a time series of dynamics, and mathematical models of complex system dynamics have a large number of unmeasured parameters and therefore have been only tenuously related to real systems. …”
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3619“…Neuromuscular control is critical in coordinating this complex system for dynamic stabilization. Comprehensive assessment and training require a multifaceted approach to address core muscle strength, endurance, and recruitment requirements for functional demands associated with daily activities, exercise, and sport.…”
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3620por Mistretta, Francesco, Buffi, Nicolò Maria, Lughezzani, Giovanni, Lista, Giuliana, Larcher, Alessandro, Fossati, Nicola, Abrate, Alberto, Dell'Oglio, Paolo, Montorsi, Francesco, Guazzoni, Giorgio, Lazzeri, Massimo“…Urothelium, in addition to its primary function of barrier, is now understood to act as a complex system of cell communication that exhibits specialized sensory properties in the regulation of physiological or pathological stimuli. …”
Publicado 2014
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