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3741Application of Soluplus to Improve the Flowability and Dissolution of Baicalein Phospholipid Complex“…In this study, a novel ternary complex system (TCS) composed of baicalein, phospholipids, and Soluplus was prepared to improve the flowability and dissolution for baicalein phospholipid complex (BPC). …”
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3742por Wierzbicka, Aneta, Pedersen, Eja, Persson, Roger, Nordquist, Birgitta, Stålne, Kristian, Gao, Chuansi, Harderup, Lars-Erik, Borell, Jonas, Caltenco, Héctor, Ness, Barry, Stroh, Emilie, Li, Yujing, Dahlblom, Mats, Lundgren-Kownacki, Karin, Isaxon, Christina, Gudmundsson, Anders, Wargocki, Pawel“…To advance the relevant research, the indoor environment must be considered a dynamic and complex system with multiple interactions. This calls for a transdisciplinary and holistic approach and effective collaboration with various stakeholders.…”
Publicado 2018
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3743por Chiappelli, Francesco“…Patient-centered translational health care in the current climate crisis depends upon defining and characterizing the allostasiome as a complex systemic process intertwined with TER. Bioinformation is timely and critical to climate crisis research in general and to TER specifically, because it informs and disseminates the best available evidence for each subject's allostasiome. …”
Publicado 2018
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3744“…A possible method for efficiently sampling the conformational space of such a complex system is metadynamics (MetaD) with path collective variables (CVs). …”
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3745“…The secretory machinery, directing the nascent polypeptide to its final destination, constitutes a highly complex system located across the eukaryotic cell. Numerous molecular identities of diverse structure and function not only build the advanced network assisting folding, maturation and secretion of polypeptides but also serve as sensors and effectors of quality control points. …”
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3746por Hauck, K., Morton, A., Chalkidou, K., Chi, Y-Ling, Culyer, A., Levin, C., Meacock, R., Over, M., Thomas, R., Vassall, A., Verguet, S., Smith, P.C.“…Health interventions often depend on a complex system of human and capital infrastructure that is shared with other interventions, in the form of service delivery platforms, such as healthcare facilities, hospitals, or community services. …”
Publicado 2019
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3747“…Thus, the fingerprint coupled with network pharmacology analysis could contribute to simplifying the complex system and providing directions for further research of QRLDD.…”
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3748“…The human body is a complex system driven by hundreds of muscles, and its control mechanisms are not sufficiently understood. …”
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3749por Vasilakis, Nikolaos, Papadimitriou, Konstantinos I., Morgan, Hywel, Prodromakis, Themistoklis“…Over the last two decades, a multitude of microfluidic devices has been proposed, each one demonstrating either a different type of dilution technique or complex system architecture based on various flow source and valving combinations. …”
Publicado 2019
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3750“…The findings are applicable to other distributed complex system simulations in which communication is modeled as a graph network.…”
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3751“…The results show that the method can screen compounds with specific activity from a complex system of medicinal plants, which is very important for the screening of new active ingredients, confirmation of new medicinal ingredients, and the in-depth development of animal and plant medicines.…”
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3752por Wiciński, Michał, Malinowski, Bartosz, Puk, Oskar, Górski, Karol, Adamkiewicz, Dawid, Chojnacki, Grzegorz, Walczak, Maciej, Wódkiewicz, Eryk, Szambelan, Monika, Adamska, Paulina, Skibińska, Kamila, Socha, Maciej, Słupski, Maciej, Pawlak-Osińska, Katarzyna“…However, despite this side effect being localized, its mechanisms are complex, systemic and involve changes in whole body. This paper summarizes how through, inter alia, alterations in the circulatory system, respiratory system, central nervous system and metabolism PPI can cause hearing impairment, which can occur in every age group and is connected with long-term use of this group of drugs. …”
Publicado 2019
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3753por Jin, Yulong, Chen, Liang, Guo, Xing, Xu, Linfeng, Zhu, Zhihua, Liu, Zhen, Cheng, Ruihua, Liu, Boping“…It was found AlCl(3)·phenetole/TiCl(4)·H(2)O exhibited activities 1.2–3 times higher than those of AlCl(3)/phenetole, and more than an order of magnitude higher than those of TiCl(4)/H(2)O, which indicated a notable synergistic effect produced in the complexed system. In addition, due to the higher activity of AlCl(3)·phenetole/TiCl(4)·H(2)O, lower coinitiator concentration and polymerization temperature, as well as higher monomer concentration were more favored for this complexed initiating system to produce polyisobutylene (PIB) with reasonable molecular weight (M(w)) and molecular weight distribution (MWD). …”
Publicado 2019
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3754por Singh, Nidhi, Kumar, Neeraj, Rathee, Garima, Sood, Damini, Singh, Aarushi, Tomar, Vartika, Dass, Sujata K., Chandra, Ramesh“…Moreover, molecular docking studies confirm the moderate binding of chalcone with BSA and the molecular dynamics simulation analysis shows the stability of the BSA–drug complex system with minimal deformability fluctuations and potential interaction by the covariance matrix. …”
Publicado 2020
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3755por Enache, Iuliana Maria, Vasile, Aida Mihaela, Enachi, Elena, Barbu, Vasilica, Stănciuc, Nicoleta, Vizireanu, Camelia“…Confocal laser microscopy displayed a complex system, with several large formations and smaller aggregates inside, consisting of biologically active compounds, lactic acid bacteria cells, and biopolymers. …”
Publicado 2020
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3756“…Significance: The human brain is a highly complex system with nonlinear, dynamic behavior. A majority of brain imaging studies employing functional near-infrared spectroscopy (fNIRS), however, have considered only the spatial domain and have ignored the temporal properties of fNIRS recordings. …”
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3757por Joanito, Ignasius, Yan, Ching-Cher Sanders, Chu, Jhih-Wei, Wu, Shu-Hsing, Hsu, Chao-Ping“…The circadian clock is a complex system that plays many important roles in most organisms. …”
Publicado 2020
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3758“…ROLE1 has paramount importance in casualty reductions, representing a complex system in current operations. This study deals with an experiment on the optimization of ROLE1 according to the key parameters of the numbers of physicians, the number of ambulances and the distance between ROLE1 and the current battlefield. …”
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3759“…The decomposition based EMO developed for MaOPs has been proved to be effective, and BBO/Complex (the biogeography based optimization for complex system, BBO/Complex) algorithm is a low complexity algorithm. …”
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3760por Mahmoodi, Seyed Abbas, Mirzaie, Kamal, Mahmoodi, Maryam Sadat, Mahmoudi, Seyed Mostafa“…FCMs are considered as one of the strongest artificial intelligence techniques for complex system modeling. In this system, an FCM based on Nonlinear Hebbian Learning (NHL) algorithm is used. …”
Publicado 2020
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