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  1. 3901
    “…SETTING: A 67-year-old male of Persian descent had a complex systemic and ocular history prior to a right penetrating keratoplasty (PK) reported here. …”
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    Trans-stromal epithelial cyst after multiple lamellar keratoplasties - Case report and review of literature
  2. 3902
    “…Group‐level obesity can be seen as an emergent property of a complex system, consisting of feedback loops between individual body weight perception, individual weight‐related behaviour and group‐level social norms (a product of group‐level ‘normal' body mass index (BMI) and sociocultural ‘ideal' BMI). …”
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    Social norms and obesity prevalence: From cohort to system dynamics models
  3. 3903
    “…Osteoporosis (OP) is a complex systemic disease characterized by a loss of bone density, leading to bone fragility and an increase risk of fractures of the hip, spine and wrist. …”
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    An emerging potential therapeutic target for osteoporosis: LncRNA H19/miR-29a-3p axis
  4. 3904
    por Wang, Pei
    Publicado 2021
    “…The identification of important nodes in a complex system can be seen as a mapping from the system to the ranking score vector of nodes, such mapping is not necessarily with explicit form. …”
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    Statistical Identification of Important Nodes in Biological Systems
  5. 3905
    “…In summary, our findings implicate a novel role for tRFs in planarian regeneration, highlighting their importance in regulating complex systemic processes. Our study adds to the catalog of posttranscriptional regulatory systems in planaria, providing valuable insights on the biogenesis and the function of tRFs in neoblasts and planarian regeneration.…”
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    Comprehensive annotation and characterization of planarian tRNA and tRNA-derived fragments (tRFs)
  6. 3906
    por Jiménez-Balado, Joan, Eich, Teal S.
    Publicado 2021
    “…In combination, these findings suggest that GABA may be the linchpin in a complex system of factors that eventually leads to the principal clinical hallmark of AD: episodic memory loss. …”
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    GABAergic dysfunction, neural network hyperactivity and memory impairments in human aging and Alzheimer’s disease
  7. 3907
    por Wang, Pei
    Publicado 2021
    “…The identification of important nodes in a complex system can be seen as a mapping from the system to the ranking score vector of nodes, such mapping is not necessarily with explicit form. …”
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    Online Artículo Texto
    Statistical Identification of Important Nodes in Biological Systems
  8. 3908
    “…The plasma membrane is a complex system involved in major biological processes, including establishing and maintaining transmembrane gradients, controlling uptake and secretion, intercellular and intracellular communication, cell to cell recognition and cell’s physical protection. …”
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    The Plasma Membrane at the Cornerstone Between Flexibility and Adaptability: Implications for Saccharomyces cerevisiae as a Cell Factory
  9. 3909
    “…The concept of the brain has shifted to a complex system where different subnetworks support the human cognitive functions. …”
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    A Structural Connectivity Disruption One Decade before the Typical Age for Dementia: A Study in Healthy Subjects with Family History of Alzheimer’s Disease
  10. 3910
    “…In the secondary, neuroprotective phase, complex systemic inflammatory cascades, direct cellular toxicity, and blood-brain barrier disruption can result in worsening perihematomal edema that can adversely affect functional outcome. …”
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    Secondary mechanisms of injury and viable pathophysiological targets in intracerebral hemorrhage
  11. 3911
    “…It is well reported that severe cases of COVID-19 frequently need critical care in the ICU to manage respiratory complications, often requiring orotracheal intubation (OTI). Due to complex systemic conditions, the patient may remain intubated for a long period of time and be placed in prone position. …”
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    Oral care and photobiomodulation protocol for the prevention of traumatic injuries and lip necrosis in critically ill patients with COVID-19: an observational study
  12. 3912
    “…According to the WHO, in a complex system, “there are so many interacting parts that it is difficult (…), to predict the behavior of the system based on knowledge of its component parts. …”
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    The Role of General Practice in Complex Health Care Systems
  13. 3913
    “…Vertebrate immunity is a complex system consisting of a mix of constitutive and inducible defences. …”
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    Between‐population differences in constitutive and infection‐induced gene expression in threespine stickleback
  14. 3914
    “…Our multi-modal approach reveals complex systemic changes after RYGB surgery and points towards potential therapeutic targets in the gut-brain system to mimic the surgery mode of action.…”
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    Roux-En-Y Gastric Bypass (RYGB) Surgery during High Liquid Sucrose Diet Leads to Gut Microbiota-Related Systematic Alterations
  15. 3915
    por Kitchener, Peter D., Hales, Colin G.
    Publicado 2022
    “…Behind the voltages and currents electrophysiologists measure is a staggeringly complex system of electromagnetic fields – these are the fundamental physics of neurons and glia in the brain. …”
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    What Neuroscientists Think, and Don’t Think, About Consciousness
  16. 3916
    “…In recent years, the renin–angiotensin system (RAS) has been proposed as a target pathway for therapeutic interventions after brain injury. The RAS is a complex system of biochemical reactions critical for several systemic functions, namely, inflammation, vascular tone, endothelial activation, water balance, fibrosis, and apoptosis. …”
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    Angiotensin-(1–7) as a Potential Therapeutic Strategy for Delayed Cerebral Ischemia in Subarachnoid Hemorrhage
  17. 3917
    “…Over the past two decades, it has come to be understood as a complex systemic disorder involving gene-environmental interactions. …”
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    DNA methylation and noncoding RNA in OA: Recent findings and methodological advances
  18. 3918
    Publicado 2020
    “…Goal: The thermoregulation mechanism is a complex system that executes vital processes in the human body. …”
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    A Structured Cleaving Mesh for Bioheat Transfer Application
  19. 3919
    “…CONCLUSION: MCM services designed to accelerate coordination and linkage or re-linkage to primary care and PN services to help navigate the complex system of HIV offered in the present study are particularly effective for minority women who lack health insurance, have low CD4 counts, and are unemployed.…”
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    Factors predicting 12-month retention in care for minority women living with HIV
  20. 3920
    “…In skin cancer care, greater interdisciplinary cooperation is required for prevention, early detection, and new complex systemic therapies. However, the implementation of innovative medical care is a major challenge, especially for rural regions with an older than average, multimorbid population, with limited mobility, that are long distances from medical facilities. …”
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    A Qualitative Needs Analysis of Skin Cancer Care from the Perspectives of Patients, Physicians, and Health Insurance Representatives—A Case Study from Eastern Saxony, Germany
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