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  1. 4121
    por Le, Minh Khoi, Nguyen, Thanh Hieu
    Publicado 2022
    “…It has been documented that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) directly invades the cardiomyocytes and most commonly damages this vital organ via complex systemic devastating mechanisms. Case presentation. …”
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    Peripartum Cardiomyopathy-Induced Cardiogenic Shock Causing Hypoxic-Ischemic Encephalopathy in a COVID-19 Patient
  2. 4122
    “…OBJECTIVE: DNA damage response (DDR) is a complex system that maintains genetic integrity and the stable replication and transmission of genetic material. m6A modifies DDR-related gene expression and affects the balance of DNA damage response in tumor cells. …”
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    Models for Predicting Response to Immunotherapy and Prognosis in Patients with Gastric Cancer: DNA Damage Response Genes
  3. 4123
    “…Being aware of the complex interaction between these factors is essential to identify players at higher risk of injury, develop adequate prevention strategies, and from a scientific point of view move from a reductionist to a complex system approach.…”
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    Injury incidence and risk factors in youth soccer players: a systematic literature review. Part II: Intrinsic and extrinsic risk factors
  4. 4124
    “…The pathogenesis of SFP includes a complex system of interactions between the body and chemical triggers such as exogenous histamine, other biogenic amines, cis-urocanic acid, salicylates, and other histamine liberators. …”
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    Molecular Mechanisms of Scombroid Food Poisoning
  5. 4125
    por He, Alex Jingwei
    Publicado 2022
    “…The phased implementation creates a ‘slower is faster’ effect, helping reduce long-term negative consequences arising from improperly managed scaling-up in a complex system. Error detection and correction and recalibration of new policy tools can support national-level policy refinement in a more robust and dynamic fashion. …”
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    Scaling-up through piloting: dual-track provider payment reforms in China’s health system
  6. 4126
    “…Emergency capability assessment is a complex system with multiple factors, variables and levels. …”
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    Study on the emergency capacity of coal mine enterprises in Longdong Area based on D-FAHP method
  7. 4127
    por Zachar, Martin, Furch, Jan
    Publicado 2023
    “…Engine oil forms a complex system with a number of features. These features consist of hydrocarbons, various natural, or synthetic polymers. …”
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    Experimental testing of irradiated engine oil using an e-beam
  8. 4128
    por Oh, Byung-Chul
    Publicado 2023
    “…Cells maintain precise intracellular Ca(2+) and PIP levels via the actions of a complex system of Ca(2+) channels, transporters, Ca(2+) ATPases, and signaling effectors, including specific lipid kinases, phosphatases, and phospholipases. …”
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    Phosphoinositides and intracellular calcium signaling: novel insights into phosphoinositides and calcium coupling as negative regulators of cellular signaling
  9. 4129
    “…In this study, we report efficient encapsulation of a complex system, consisting of isoniazid-hydrazone-phthalocyanine conjugate (Pc-INH) in gamma-cyclodextrin (γ-CD), in liposomes using crude soybean lecithin by means of a simple organic solvent-free method, heating method (HM). …”
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    Encapsulation of Isoniazid-conjugated Phthalocyanine-In-Cyclodextrin-In-Liposomes Using Heating Method
  10. 4130
    “…Since cancer is a complex systemic disease, the need for new therapeutic modalities that can target or block several steps of cancer cell characteristics, modulate or repolarize immune cells, and are less toxic to healthy tissues is essential. …”
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    Pleiotropic Anticancer Properties of Scorpion Venom Peptides: Rhopalurus princeps Venom as an Anticancer Agent
  11. 4131
    “…We hypothesize that factors related to ethnicity, environment, behaviors, associated illness, and medications involving this complex system are probably responsible for situations regarded as anomalous from both an epidemiological and a clinical point of view, but, taken together, such factors may explain most of the aspects of current outbreak. …”
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    Renin-angiotensin system at the heart of COVID-19 pandemic
  12. 4132
    por Nicoletti, Marcello
    Publicado 2020
    “…The network is in continuous change due to internal and external pressures, causing a dynamic complex system. Inside the network we can focus on determinant parts of the system, wherein the rules are the same, but the number of involved subjects can be restricted. …”
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    Bionetworks, system biology, and superorganisms
  13. 4133
    “…Our study provides a comprehensive empirical analysis on the impact of the COVID-19 pandemic on aviation from a complex system perspective using network science tools.…”
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    How did COVID-19 impact air transportation? A first peek through the lens of complex networks
  14. 4134
    “…To investigate the underlying biological mechanisms involved in such complex system, there is need of predicting biological response by integrated Monte Carlo (MC) simulations across physics, chemistry and biology. …”
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    Fully integrated Monte Carlo simulation for evaluating radiation induced DNA damage and subsequent repair using Geant4-DNA
  15. 4135
    por Alexandre, Frederic
    Publicado 2021
    “…The brain is a complex system, due to the heterogeneity of its structure, the diversity of the functions in which it participates and to its reciprocal relationships with the body and the environment. …”
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    A global framework for a systemic view of brain modeling
  16. 4136
    “…These results highlight the importance of an integrated, systems-level approach to understanding host-microbe interactions, with an appreciation for important variables, such as reproductive hormones, in the complex system of the FGT mucosa.…”
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    Antigen Presenting Cells Link the Female Genital Tract Microbiome to Mucosal Inflammation, With Hormonal Contraception as an Additional Modulator of Inflammatory Signatures
  17. 4137
    “…The interaction between residential preferences and dwellings is a complex system whose function thus far remains insufficiently explored. …”
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    Tenants’ residential mobility in Switzerland: the role of housing functions
  18. 4138
    “…Acute ischemic stroke triggers complex systemic pathological responses for which the exploration of drug resources remains a challenge. …”
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    Vespakinin-M, a natural peptide from Vespa magnifica, promotes functional recovery in stroke mice
  19. 4139
    “…The human body is a complex system maintained in homeostasis thanks to the interactions between multiple physiological regulation systems. …”
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    Physiological Network Is Disrupted in Severe COVID-19
  20. 4140
    “…The tumor microenvironment (TME) represents a complex system whose function is not yet well defined and where microvesicles, such as exosomes, play a key role in intercellular communication. …”
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    Growth Inhibition of Retinoblastoma Cell Line by Exosome-Mediated Transfer of miR-142-3p
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