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4181por Kien, Christina, Nußbaumer, Barbara, Thaler, Kylie J, Griebler, Ursula, Van Noord, Megan G, Wagner, Petra, Gartlehner, Gerald“…CONCLUSIONS: Publication bias is a complex problem that reflects the complex system in which it occurs. The cooperation amongst stakeholders to increase public awareness of the problem, better tailoring of incentives to publish, and ultimately legislative regulations have the greatest potential for reducing publication bias. …”
Publicado 2014
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4182por Ramos, María-Paz, Wijetunga, Neil Ari, McLellan, Andrew S, Suzuki, Masako, Greally, John M“…CONCLUSIONS: Our results do not support the hypothesis of DNA methylation having a predominant role to regulate transcriptional noise in the genome and indicate that DNA methylation acts only as part of a larger complex system of transcriptional regulation. The targeting of 5-aza-CdR effects with its clastogenic consequences to euchromatin raises concerns that the use of 5-aza-CdR has innate tumorigenic consequences, requiring its cautious use in diseases involving epigenetic dysregulation. …”
Publicado 2015
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4183por Khalaf, Kinda, Jelinek, Herbert F., Robinson, Caroline, Cornforth, David J., Tarvainen, Mika P., Al-Aubaidy, Hayder“…The cardiovascular system may be viewed as a complex system comprising a number of interacting subsystems. …”
Publicado 2015
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4184por Cohen, Alan A., Li, Qing, Milot, Emmanuel, Leroux, Maxime, Faucher, Samuel, Morissette-Thomas, Vincent, Legault, Véronique, Fried, Linda P., Ferrucci, Luigi“…Biologically, the lack of sensitivity to marker choice and better performance of younger, healthier RPs confirm an interpretation of D(M) physiological dysregulation and as an emergent property of a complex system.…”
Publicado 2015
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4185por Liu, Yuan, Ye, Josephine, Shin Ogawa, Luisa, Inoue, Takayo, Huang, Qin, Chu, John, Bates, Richard C., Ying, Weiwen, Sonderfan, Andrew J., Rao, Patricia E., Zhou, Dan“…Systemic lupus erythematosus (SLE) is a complex, systemic autoimmune disease with a diverse range of immunological and clinical manifestations. …”
Publicado 2015
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4186“…Our results expand the molecular mechanisms of stress coping from one focused on the neurotransmitter systems to a more complex system that involves an organism’s capability to handle neurometabolic loads and allows for comparisons with other animal taxa to uncover potential conserved mechanisms. …”
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4187por Hermand, Eric, Lhuissier, François J, Larribaut, Julie, Pichon, Aurélien, Richalet, Jean-Paul“…An intrinsic oscillator might modulate ventilation through a complex system where peripheral chemoreflex would play a key role.…”
Publicado 2015
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4188por Aziz, Fatma A. A., Suzuki, Kenshi, Ohtaki, Akihiro, Sagegami, Keita, Hirai, Hidetaka, Seno, Jun, Mizuno, Naoko, Inuzuka, Yuma, Saito, Yasuhisa, Tashiro, Yosuke, Hiraishi, Akira, Futamata, Hiroyuki“…This study investigated the factors that determine the dynamics of bacterial communities in a complex system using multidisciplinary methods. Since natural and engineered microbial ecosystems are too complex to study, six types of synthetic microbial ecosystems (SMEs) were constructed under chemostat conditions with phenol as the sole carbon and energy source. …”
Publicado 2015
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4189por Okada, Taketo, Afendi, Farit Mochamad, Yamazaki, Mami, Chida, Kaori Nakahashi, Suzuki, Makoto, Kawai, Rika, Kim, Miyuki, Namiki, Takao, Kanaya, Shigehiko, Saito, Kazuki“…Our results show that factor analysis of Kampo concepts and of the metabolomes of Kampo medicines enables interpretation of the complex system of Kampo. This study will theoretically form the basis for establishing traditionally and empirically based medications worldwide, leading to systematically personalized medicine. …”
Publicado 2015
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4190“…A complex system of multiple signaling molecules often produce differential gene expression patterns in animal embryos. …”
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4191por Carey, Gemma, Malbon, Eleanor, Carey, Nicole, Joyce, Andrew, Crammond, Brad, Carey, Alan“…RESULTS: 4 categories of research were identified from the review, ranging from editorial and commentary pieces to complex system dynamic modelling. Our analysis of each of these categories of research highlighted areas of potential for systems science to strengthen public health efforts, while also revealing a number of limitations in the dynamic systems modelling being carried out in public health. …”
Publicado 2015
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4192“…CONCLUSION: Indoctrination of newly abducted children into the LRA occurs via a complex system of control. This study provides one of the first detailed explorations of social and psychological mechanisms through which this is achieved, and focuses particularly on the gendered differences in the indoctrination process. …”
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4193“…In particular, the results showed how their engagement in health promotion is framed in a complex system of psychological meanings, which may sustain or hinder their ability to adopt healthy behaviours. …”
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4194por Geng, Haifeng, Tran-Gyamfi, Mary B., Lane, Todd W., Sale, Kenneth L., Yu, Eizadora T.“…Open microalgae cultures host a myriad of bacteria, creating a complex system of interacting species that influence algal growth and health. …”
Publicado 2016
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4195“…Additionally, we measure free acetate in tissues and bio-fluids and show that there are considerable differences in acetate concentrations between organs in vivo, providing insights into its complex systemic metabolism and availability for various types of tumors. …”
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4196por Rovida, Elisabetta, Marzi, Ilaria, Cipolleschi, Maria Grazia, Dello Sbarba, Persio“…This is a review (by no means comprehensive) of how the stem cell niche evolved from an abstract concept to a complex system, implemented with a number of experimental data at the cellular and molecular levels, including metabolic cues, on which we focused in particular. …”
Publicado 2014
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4197“…Our results provided new facts and insights into this unique community of mesocarnivores of southwest China, and will facilitate future studies on the mechanism determining coexistence of animal species within complex system.…”
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4198por De Castro, Olga, Di Maio, Antonietta, Di Febbraro, Mirko, Imparato, Gennaro, Innangi, Michele, Véla, Errol, Menale, Bruno“…The Mediterranean coastline is a dynamic and complex system which owes its complexity to its past and present vicissitudes, e.g. complex tectonic history, climatic fluctuations, and prolonged coexistence with human activities. …”
Publicado 2016
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4199por Gérikas Ribeiro, Catherine, Lopes dos Santos, Adriana, Marie, Dominique, Helena Pellizari, Vivian, Pereira Brandini, Frederico, Vaulot, Daniel“…The hydrography in this region is dominated by a complex system of layered water masses, which includes the warm and oligotrophic Tropical Water (TW), the cold and nutrient rich South Atlantic Central Water (SACW) and the Coastal Water (CW), which have highly variable properties. …”
Publicado 2016
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4200por Affifi, Ramsey“…Far from merely a disturbance brought about in a senseless albeit complex system, a biosemiotic view would take “side effects” as at least sometimes the organism’s active re-organization in order to accommodate or make use of novelty. …”
Publicado 2016
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