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  1. 4281
    “…Endometriosis (EM) is one of the vanquished wonted causes of chronic pelvic sting in women and is closely associated with infertility. The long-term, complex, systemic, and post-treatment recurrence of EM wreaks havoc on women’s quality of life. …”
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    Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis
  2. 4282
    “…We presented an operational rationale grounded on complex system thinking to quantify structural and functional landscape transformations along three stages representative of post-war metropolitan development in Rome, Italy (urbanisation with population/settlement densification, 1949–1974; suburbanisation with medium-density settlement expansion, 1974–1999; counter-urbanisation with settlement sprawl, 1999–2016). …”
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    Investigating metropolitan change through mathematical morphology and a dynamic factor analysis of structural and functional land-use indicators
  3. 4283
    “…We identified the following barriers for effective use of PSLS: inadequate organisational support with shortage of resources, lack of training, weak safety culture, lack of accountability, defective policies, blame and a punitive environment, complex system, lack of experience and lack of feedback. …”
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    Barriers and facilitators to improving patient safety learning systems: a systematic review of qualitative studies and meta-synthesis
  4. 4284
    “…The genetic diversity of H9N2 viruses was greater at the retail LPMs, where a complex system of two-way transmission between different poultry species had formed. …”
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    Mixed selling of different poultry species facilitates emergence of public-health-threating avian influenza viruses
  5. 4285
    “…The basal ganglia is part of a complex system of neuronal circuits that play a key role in the integration and execution of motor, cognitive and emotional function in the human brain. …”
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    In vivo Exploration of the Connectivity between the Subthalamic Nucleus and the Globus Pallidus in the Human Brain Using Multi-Fiber Tractography
  6. 4286
    “…Insights into the mechanism of action of natural products and their derivatives will enhance our understanding of this complex system and will improve our ability to rationally design novel inhibitors. …”
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    Natural Product Inhibitors of Ubiquitin Conjugation and Deconjugation
  7. 4287
    “…CONCLUSION: Identifying the nature and extent of youth MHA issues, service needs, and family preferences can inform the development of services that address families’ needs and lend vital support for accessing services within a complex system.…”
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    The needs and service preferences of caregivers of youth with mental health and/or addictions concerns
  8. 4288
    “…CONCLUSIONS: Metformin generates complex systemic and local immune effects which vary as a function of treatment duration. …”
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    Metformin generates profound alterations in systemic and tumor immunity with associated antitumor effects
  9. 4289
    “…Methods on modelling the human brain as a Complex System have increased remarkably in the literature as researchers seek to understand the underlying foundations behind cognition, behaviour, and perception. …”
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    Spatiotemporal dynamics in spiking recurrent neural networks using modified-full-FORCE on EEG signals
  10. 4290
    “…The Sustainable Development Goals (SDGs) present a complex system of 17 goals and 169 individual targets whose interactions can be described in terms of co-benefits and trade-offs between policy actions. …”
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    System-level consequences of synergies and trade-offs between SDGs: quantitative analysis of interlinkage networks at country level
  11. 4291
    “…BACKGROUND: Implementing competency-based medical education (CBME) in post-graduate medical education (PGME) is a complex process that requires multiple systemic changes in a complex system that is simultaneously engaged in multiple initiatives. …”
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    Rivalries for attention: insights from a realist evaluation of a postgraduate competency-based medical education implementation in Canada
  12. 4292
    “…Dietary surveys are conducted to examine the population’s dietary patterns that require a complex system of databases, and rules for constructing the data matrix (precision, coding, deriving new variables, e.g., body mass index from individual’s height and weight, classes, e.g., age-class, socio-economic status, physical activity, etc.). …”
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    Dietary assessment training: The Italian IV SCAI study on 10–74 year-old individuals’ food consumption
  13. 4293
    “…Type 2 diabetes is a complex, systemic disease affected by both genetic and environmental factors. …”
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    Novel diabetes gene discovery through comprehensive characterization and integrative analysis of longitudinal gene expression changes
  14. 4294
    “…Especially the NR3C1 transcript seemed to be a key element in this complex system. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00406-022-01420-w.…”
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    The interplay between genetic variation and gene expression of the glucocorticoid receptor gene NR3C1 and blood cortisol levels on verbal memory and hippocampal volumes
  15. 4295
    “…Most of the respondents (89.5%) knew that the most likely diagnosis for a child with red eyes and a discharge is viral conjunctivitis and that pain, blurred vision, and a clouded cornea, are symptoms indicative of a more complex systemic problem. In contrast, 78.3% of the pediatricians claimed that the treatment of choice for viral conjunctivitis is a conservative treatment that includes eye flushing and strict hygiene. …”
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    Pediatricians’ knowledge, attitude and practice on treating children with red eye disease
  16. 4296
    por Mirra, Marco
    Publicado 2017
    “…Backgrounds, which are up to 10^10 times higher than the signal, will be suppressed by an accurate measurement of the momentum of the K+ (with a silicon beam tracker named GigaTracker) and the π+ (with a straw tracker) and by a complex system of particle identification and veto detectors. …”
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    CHANTI: a fast and efficient charged particle veto detector for the NA62 experiment at cern
  17. 4297
    “…The existing and complex system, attributed to WHO, was developed more than three decades ago and did not consider more than 30 years of research into these disorders in addition to technical advances in imaging and endocrinology. …”
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    The FIGO ovulatory disorders classification system
  18. 4298
    “…The quality control of mitochondria involves a complex system of pathways, including mitophagy, mitochondrial biogenesis, fusion/fission dynamics, and regulation of gene expression. …”
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    Mitochondrial quality control in lung diseases: current research and future directions
  19. 4299
    “…Objectives were to (a) build shared understanding of the complex system influencing the public health impact of the Connswater Community Greenway, and (b) identify and explore priorities, opportunities, and actions to improve future impacts. …”
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    5 year public health impacts of an urban greenway, Belfast, Northern Ireland: Causal Loop Diagram
  20. 4300
    “…It allows to study specific patterns and the structure of complex system in order to better understand how the elements of the system interact with each-other. …”
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    Item-specific patterns of the Skindex-17 in individuals with different levels of Hidradenitis Suppurativa severity: a network analysis study
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