“…Systems Thinking (ST) can be defined as a mental construct that recognises patterns and connections in a particular complex system to make the “best decision” possible. In the field of sustainable agriculture and climate change, higher degrees of ST are assumed to be associated with more successful adaptation strategies under changing conditions, and “better” environmental decision making in a number of environmental and cultural settings. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We discuss our results in light of probabilistic information processing and complex system properties, and suggest that a general description of brain activity must account for variability in modulation directions at both the group and individual levels.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The intricate complex system of the differentiation 47 (CD47) and the signal-regulatory protein alpha (SIRPα) cluster is a crucial target for cancer immunotherapy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…KEY MESSAGES: • The SARI surveillance system is a resource intensive, complex system that is an important component of national surveillance in Ireland and reports high-quality and timely surveillance data. • The priorities for expansion are process automation where possible and ensuring adequate resources, specifically skilled staff. …”
Enlace del recurso
Enlace del recurso

“…To understand this complex system, we performed comparative transcriptomic analysis with various rhizotoxic ions, followed by bioinformatics analysis, in the model plant Arabidopsis thaliana. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, both organisms have characteristics indicative of a complex system in calcium regulation. This study investigated PTH family evolution in vertebrates with special emphasis on Xenopus and chicken. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…When we talk about drug addiction, we are really dealing with an extremely complex system in which there still remain many unknowns and where many empty spaces or missing links are still present. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The modeling process enhanced understanding by a range of stakeholders of cycling as a complex system. Participatory SDM can be a helpful method for integrating health and environmental outcomes in transport and urban planning. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Overall, our results emphasize that mandible shape and integration evolved as parts of a complex system including mechanical loading food resource utilization and possibly foraging behaviour.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…According to the results of our study, FPase is a major component of cellulose hydrolytic enzyme complex system and the reducing sugar rate-limiting enzyme. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Localized expression domains during gastrulation and larval development evidence early regionalization of the mesoderm and provide a basis for hypotheses regarding the molecular regulation underlying the complex system of musculature observed in the larva. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13227-015-0004-8) contains supplementary material, which is available to authorized users.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, the currently used approaches to identify miRNAs in this polyploid complex system focus on conserved and highly expressed miRNAs avoiding regularly those that are often lineage-specific, condition-specific, or appeared recently in evolution. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Modeling of the immune system – a highly non-linear and complex system – requires practical and efficient data analytic approaches. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: We found that ART program sustainability was embedded in a complex system involving dynamic interactions between internal (program champion, staffing strength, M &E systems, goal clarity) and external drivers (donors, ARVs supply chain, patient demand). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…It is well known that the brain is best modeled as a complex system. Therefore a measure of complexity using rs-BOLD signal FD could provide an additional method to grade and monitor mTBI. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: We identified four themes around opioid use: (1) attitudes toward use of opioids to manage chronic pain; (2) the limited alternative options for chronic pain management; (3) the potential of A/C care as a tool to help manage pain; and (4) the complex system around chronic pain management. Despite widespread dissatisfaction with opioid medications for pain management, many practical barriers challenged access to other options. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Future safety improvement interventions should focus on how to maximise practice-level knowledge and understanding of the range of context-specific approaches available and the safeties and risks inherent in each within the context of wider complex system conditions and interactions. This in turn has the potential to inform new kinds of proactive, contextually appropriate approaches to intervention development and implementation focusing on the enhanced deliberation of the safety of existing high-volume routines.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Language has also been conceived and studied as a complex system. However, most proposals do not analyze language according to linguistic theory, but use instead computational systems that should save time at the price of leaving aside many crucial aspects for linguistic theory. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In Germany, about 68,000 patients die annually because of septic diseases, characterized by a complex systemic inflammatory response. Causal treatment of the underlying infection is essential for successful management of sepsis, but the course can be positively influenced by supportive and adjuvant measures. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: We provide a worked example of methods for the development of future complex interventions in primary care, where multiple factors act on multiple actors within a complex system. Our synthesis provided intervention guidance, recommendations for practice, and highlighted evidence gaps, but questions remain about how best to implement these recommendations. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso