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301por Zhao, Wan, Huang, Ling, Li, Yang, Zhang, Qiumei, Chen, Xiongying, Fu, Wenjin, Du, Boqi, Deng, Xiaoxiang, Ji, Feng, Xiang, Yu‐Tao, Wang, Chuanyue, Li, Xiaohong, Dong, Qi, Chen, Chuansheng, Jaeggi, Susanne M., Li, Jun“…CONCLUSIONS: This study provided evidence for the neural effect of a visual–spatial span training and suggested that genetic factors such as the COMT Val158/108Met polymorphism may have to be considered in future studies of such training.…”
Publicado 2020
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302por Tsai, Meng-Che, Jhang, Kai-Jyun, Lee, Chih-Ting, Lin, Yu-Fang, Strong, Carol, Lin, Yi-Ching, Hsieh, Yi-Ping, Lin, Chung-Ying“…Salivary genomic DNA was used to test polymorphisms in MAOA, BDNF, and COMT genes. A gene score (GS) was created based on the number of risk allele in the studied genes. …”
Publicado 2020
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303“…However, the subgroup with COMT val/val (low dopamine) were less accurate on 2-back lure trials than those with COMT met/met (high dopamine). …”
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304por Khasin, Maya, Bernhardson, Lois F., O’Neill, Patrick M., Palmer, Nathan A., Scully, Erin D., Sattler, Scott E., Funnell-Harris, Deanna L.“…Two null alleles in monolignol biosynthesis of sorghum (brown midrib 6-ref, bmr6-ref; cinnamyl alcohol dehydrogenase, CAD; and bmr12-ref; caffeic acid O-methyltransferase, COMT) were used to investigate the interaction of water limitation with F. thapsinum or M. phaseolina infection. …”
Publicado 2021
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305por Wiegand, Ariane, Blickle, Arne, Brückmann, Christof, Weller, Simone, Nieratschker, Vanessa, Plewnia, Christian“…We observed a continuous increase in COMT promotor DNA methylation which correlated with higher saliva cortisol levels and was still detectable one week later. …”
Publicado 2021
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306por Kant, Tuana, Koyama, Emiko, Zai, Clement C., Beitchman, Joseph H., Kennedy, James L.“…The literature shows inconsistent findings, making the interpretation of COMT’s role difficult. The aims of this article are (i) to conduct a systematic review to analyze the effects of COMT Val158Met on psychopathic traits in children and adolescents, and (ii) to present new evidence on the developmental trajectory of the association of Val158Met and youth psychopathic traits. …”
Publicado 2022
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307“…CONCLUSION: The MB-COMT promotor, DRD2, and NR3C1 gene methylation status may be associated with the SCZ in the Turkish population.…”
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310“…METHODS AND RESULTS: SCZ-associated genes (HTR2A, COMT, and PRODH) were subjected to pan-cancer analysis. …”
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311por Mobascher, Arian, Brinkmeyer, Juergen, Thiele, Holger, Toliat, Mohammad R, Steffens, Michael, Warbrick, Tracy, Musso, Francesco, Wittsack, Hans-Joerg, Saleh, Andreas, Schnitzler, Alfons, Winterer, Georg“…In the present fMRI study we therefore sought to investigate the impact of the COMT val(158)met polymorphism on the blood oxygen level-dependent (BOLD) response to painful laser stimulation. …”
Publicado 2010
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312“…The sources of these stable individual differences in delay discounting (DD) are largely unknown. One candidate is the COMT Val158Met polymorphism, known to modulate prefrontal dopamine levels and affect DD. …”
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313“…The common catechol-O-methyltransferase (COMT) val158met polymorphism is known to influence COMT activity and therefore the degradation of DA. …”
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314por El‐Hage, Wissam, Cléry, Helen, Andersson, Frederic, Filipiak, Isabelle, Thiebaut de Schotten, Michel, Gohier, Benedicte, Surguladze, Simon“…The main objective of this study was to examine the effect of Val158Met (rs4680) polymorphism of Catechol‐O‐Methyltransferase (COMT) gene on white matter connectivity in healthy adults. …”
Publicado 2017
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315por Xu, Jiayue, Boström, Adrian E., Saeed, Mohamed, Dubey, Raghvendra K., Waeber, Gérard, Vollenweider, Peter, Marques-Vidal, Pedro, Mwinyi, Jessica, Schiöth, Helgi B.“…Participants were genotyped for the catechol-O-methyltransferase gene (COMT) variants rs4680, rs737865, and rs165599; the uridine-diphospho-glucuronosyltransferase 1A gene family (UGT1A) variants rs2070959 and rs887829; and the aromatase gene (CYP19A1) variant rs10046. …”
Publicado 2017
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316“…After one session of tDCS, significant group differences in WM performance were predicted by COMT val(158)met status. One month after training, there was a significant interaction of tDCS intensity, COMT genotype, and WM task. …”
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317por Zhang, Kunlin, Wang, Li, Cao, Chengqi, Li, Gen, Fang, Ruojiao, Liu, Ping, Luo, Shu, Zhang, Xiangyang, Liberzon, Israel“…Results: Statistical genetics analysis identified a DRD2/ANNK1–COMT interaction (rs1800497 × rs6269), which is associated with PTSD diagnosis (P(interaction) = 0.0008055 and P(corrected) = 0.0169155). …”
Publicado 2018
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318por Porter, Tenielle, Burnham, Samantha C., Milicic, Lidija, Savage, Greg, Maruff, Paul, Sohrabi, Hamid R., Peretti, Madeline, Lim, Yen Ying, Weinborn, Michael, Ames, David, Masters, Colin L., Martins, Ralph N., Rainey-Smith, Stephanie, Rowe, Christopher C., Salvado, Olivier, Groth, David, Verdile, Giuseppe, Villemagne, Victor L., Laws, Simon M.“…The non-synonymous single nucleotide polymorphism (SNP), Val158Met within the Catechol-O-methyltransferase (COMT) gene has been associated with altered levels of cognition and memory performance in cognitively normal adults. …”
Publicado 2019
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319por Qi, Rongfeng, Luo, Yifeng, Zhang, Li, Weng, Yifei, Surento, Wesley, Li, Lingjiang, Cao, Zhihong, Lu, Guang Ming“…Participants were divided into subgroups according to their COMT rs4680 and BDNF rs6265 genotypes. Degree Centrality (DC)—a resting-state fMRI index reflecting the brain network communication—was compared with a three-way (PTSD diagnosis, COMT, and BDNF polymorphisms) analysis of covariance. …”
Publicado 2020
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320“…Moreover, the catechol-O-methyltransferase (COMT) Val158Met polymorphism related to depressive symptoms may also exert a moderating effect on NSSI; thus, the interaction between harsh parenting and COMT was also considered in our study. …”
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