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  1. 4881
    “…BACKGROUND: With the recent occurrence of locally transmitted Aedes-borne viruses in the continental United States and Europe, and a lack of effective vaccines, new approaches to control Aedes aegypti and Aedes albopictus are needed. …”
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    Experimental evaluation of a metofluthrin passive emanator against Aedes albopictus
  2. 4882
    “…Our study presents continental-scale conservation priorities for freshwater ecosystems in ecologically meaningful planning units and will thus be important in freshwater biodiversity conservation policy and practice, and water management in Europe.…”
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    Spatial priorities for freshwater biodiversity conservation in light of catchment protection and connectivity in Europe
  3. 4883
    “…We provide a brief historical perspective on the development of Connectom gradient technology and the efforts that led to the installation of three other Connectom 3T MRI scanners worldwide – one in the United Kingdom in Cardiff, Wales, another in continental Europe in Leipzig, Germany, and the latest in Asia in Shanghai, China. …”
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    Mapping the human connectome using diffusion MRI at 300 mT/m gradient strength: Methodological advances and scientific impact
  4. 4884
    “…In Brazil, epidemiological studies are outdated and restricted to specific regions, mostly due to the continental size of country. OBJECTIVE: We aimed to present the first evidence-based study on the epidemiological aspects of individuals with epilepsy, mapping the characteristics of this disease in a referral center in a region of Southeast Brazil. …”
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    Epidemiologic Profile of Patients With Epilepsy in a Region of Southeast Brazil: Data From a Referral Center
  5. 4885
    “…Currently available genetic tools effectively distinguish between different continental origins. However, North Eurasia, which constitutes one-third of the world’s largest continent, remains severely underrepresented. …”
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    Determining the Area of Ancestral Origin for Individuals From North Eurasia Based on 5,229 SNP Markers
  6. 4886
    “…Governments and stakeholders across continental Africa should therefore prioritize the allocation of available resources to institute educational programs and other intervention strategies for preventing and ameliorating universal distress and promoting psychological wellbeing. …”
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    Prevalence of Anxiety and Depression Among the General Population in Africa During the COVID-19 Pandemic: A Systematic Review and Meta-Analysis
  7. 4887
    “…Notably, island populations have lower population sizes than continental groups and most hunter-gatherer, nomadic and indigenous groups have evidence of recent founder events. …”
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    Reconstructing the history of founder events using genome-wide patterns of allele sharing across individuals
  8. 4888
    “…To demonstrate FISH-TAMB’s ability to label intracellular mRNA targets, differentiate transcriptional states, detect active and rare taxa, and keep cell viability, labeling experiments were performed that targeted the messenger RNA (mRNA) of methyl-coenzyme M reductase A (mcrA) expressed in (1) Escherichia coli containing a plasmid with a partial mcrA gene of the methanogen Methanosarcina barkeri (E. coli mcrA(+)); (2) M. barkeri; and (3) an anaerobic methanotrophic (ANME) enrichment from a deep continental borehole. Although FISH-TAMB was initially envisioned for mRNA of any functional gene of interest without a requirement of prior knowledge of 16S ribosomal RNA (rRNA)-based taxonomy, FISH-TAMB has the potential for multiplexing and going beyond mRNA and thus is a versatile addition to the molecular ecologist’s toolkit, with potentially widespread application in the field of environmental microbiology. …”
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    FISH-TAMB, a Fixation-Free mRNA Fluorescent Labeling Technique to Target Transcriptionally Active Members in Microbial Communities
  9. 4889
    “…For this purpose, we characterized the fungal communities of Pinus pinaster trees infected and non-infected with PWN in three collection sites in Continental Portugal with different PWD temporal incidences. …”
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    Fungal Communities of the Pine Wilt Disease Complex: Studying the Interaction of Ophiostomatales With Bursaphelenchus xylophilus
  10. 4890
    “…When combined, our results suggest areas in the PPR that currently support the highest densities of intact wetland basins, and thus support the largest numbers of breeding‐duck pairs, will likely also be the places most critical to maintaining continental waterfowl populations in an uncertain future.…”
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    Limited shifts in the distribution of migratory bird breeding habitat density in response to future changes in climate
  11. 4891
    “…Sampling was at up to 50 m depth and covered approximately 10,000 km of the continental shelf of Australia. Seascape relief, water depth, and human gravity (i.e., a proxy of human impacts) were the strongest predictors of the probability of occurrence of large fishes and the abundance of fishes above the minimum legal size of capture. …”
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    Effects of human footprint and biophysical factors on the body‐size structure of fished marine species
  12. 4892
    “…Standpoints established through this study will enrich basic datasets for further studies at the continental level. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12665-022-10481-y.…”
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    Validating local drivers influencing land use cover change in Southwestern Ghana: a mixed-method approach
  13. 4893
    “…Gradual niche differentiation from the coldest and most continental populations of H. iberica to the warm and stable coastal population sister to H. maderensis parallels the geographical pattern observed in the phylogeny. …”
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    Climatic niche pre-adaptation facilitated island colonization followed by budding speciation in the Madeiran ivy (Hedera maderensis, Araliaceae)
  14. 4894
    “…Seed mass from sites with low precipitation was smaller than that from sites with higher precipitation and was better explained by rainfall continentality than by aridity in summer. Within-population variability in seed germination accounted for 5 to 54%, while for seed mass it was lower than 40%. …”
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    Within-species variation of seed traits of dune engineering species across a European climatic gradient
  15. 4895
    por Kim, Michelle S., Naidoo, Daphne, Hazra, Ujani, Quiver, Melanie H., Chen, Wenlong C., Simonti, Corinne N., Kachambwa, Paidamoyo, Harlemon, Maxine, Agalliu, Ilir, Baichoo, Shakuntala, Fernandez, Pedro, Hsing, Ann W., Jalloh, Mohamed, Gueye, Serigne M., Niang, Lamine, Diop, Halimatou, Ndoye, Medina, Snyper, Nana Yaa, Adusei, Ben, Mensah, James E., Abrahams, Afua O. D., Biritwum, Richard, Adjei, Andrew A., Adebiyi, Akindele O., Shittu, Olayiwola, Ogunbiyi, Olufemi, Adebayo, Sikiru, Aisuodionoe-Shadrach, Oseremen I., Nwegbu, Maxwell M., Ajibola, Hafees O., Oluwole, Olabode P., Jamda, Mustapha A., Singh, Elvira, Pentz, Audrey, Joffe, Maureen, Darst, Burcu F., Conti, David V., Haiman, Christopher A., Spies, Petrus V., van der Merwe, André, Rohan, Thomas E., Jacobson, Judith, Neugut, Alfred I., McBride, Jo, Andrews, Caroline, Petersen, Lindsay N., Rebbeck, Timothy R., Lachance, Joseph
    Publicado 2022
    “…However, natural selection is not the primary driver of these differences. Comparing continental datasets, we find that polygenic predictions of case vs. control status are more effective for European individuals (AUC 0.608–0.707, OR 2.37–5.71) than for African individuals (AUC 0.502–0.585, OR 0.95–2.01). …”
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    Testing the generalizability of ancestry-specific polygenic risk scores to predict prostate cancer in sub-Saharan Africa
  16. 4896
    “…METHODS: This was a multicenter cross-sectional study involving 468 healthy volunteers (age range: 18-79 years) recruited from the general community in six research laboratories across different regions of Brazil, which is a country with continental dimensions. The 6MST was performed twice (30-min interval), and clinical, demographic, and functional variables were evaluated. …”
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    Normative values and reference equation for the six-minute step test to evaluate functional exercise capacity: a multicenter study
  17. 4897
    “…Swallowtail butterflies are among the most studied insects, and they are a model group for evolutionary biology and ecology studies. Continental macroecological rules are normally tested using vertebrates, this means that there are fewer examples exploring terrestrial invertebrate patterns at global scale. …”
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    A phylogenetic study to assess the link between biome specialization and diversification in swallowtail butterflies
  18. 4898
    “…Here we studied temporal variability in cryptobenthic coral reef communities across the continental shelf in the central Red Sea spanning 6 years (three sampling periods: 2013–2019) and including the 2015 mass bleaching event. …”
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    Inter-annual variability patterns of reef cryptobiota in the central Red Sea across a shelf gradient
  19. 4899
    “…The continental subsurface harbors microbial populations highly enriched in uncultured taxa. …”
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    The first cultivated representatives of the actinobacterial lineage OPB41 isolated from subsurface environments constitute a novel order Anaerosomatales
  20. 4900
    “…Research effort was significantly biased towards lion (Panthera leo) and against striped hyaena (Hyaena hyaena), despite the latter being the species with the widest continental range. African wild dog (Lycaon pictus) also exhibited a negative bias in research attention, although this was partly explained by its relatively restricted distribution. …”
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    Trends and biases in African large carnivore population assessments: identifying priorities and opportunities from a systematic review of two decades of research
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