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Mostrando 341 - 360 Resultados de 1,534 Para Buscar '"Control Data"', tiempo de consulta: 2.44s Limitar resultados
  1. 341
    “…In terms of scope, KELVIN supports two-point (trait-marker or marker-marker) and multipoint linkage analysis, based on either sex-averaged or sex-specific genetic maps, with an option to allow for imprinting; trait-marker linkage disequilibrium (LD), or association analysis, in case-control data, trio data, and/or multiplex family data, with options for joint linkage and trait-marker LD or conditional LD given linkage; dichotomous trait, quantitative trait and quantitative trait threshold models; and certain types of gene-gene interactions and covariate effects. …”
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    KELVIN: A Software Package for Rigorous Measurement of Statistical Evidence in Human Genetics
  2. 342
    por Cheng, KF, Lee, JY
    Publicado 2012
    “…CONCLUSION: Our results show that the bias cannot be ignored even the case and control data were matched in ethnicity. A real example is given to illustrate application of the conservative p-value. …”
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    Assessing the joint effect of population stratification and sample selection in studies of gene-gene (environment) interactions
  3. 343
    “…We conduct a genome-wide association study of Genetic Analysis Workshop 17 case-control data produced by the next-generation sequencing technique and propose that collapsing rare variants within each genetic region through a supervised dimension reduction algorithm leads to several macrovariants constructed for rare variants within each genetic region. …”
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    Genome-wide case-control study in GAW17 using coalesced rare variants
  4. 344
    “…BPA effect on the activity of antioxidant genes was confirmed by real time PCR in which the expression levels of these genes in liver tissue were significantly decrease compared to control. Data from this study demonstrate that BPA generate ROS and reduce the antioxidant gene expression that causes hepatotoxicity.…”
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    Bisphenol A Induces Hepatotoxicity through Oxidative Stress in Rat Model
  5. 345
    “…We found little evidence for individual or systematic inflated association findings resulting from using public controls, demonstrating the utility of using public control data in large-scale genetic association studies of common variants. …”
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    Genome-Wide Association Scan for Variants Associated with Early-Onset Prostate Cancer
  6. 346
    “…Treatments, including coenzyme Q, have had some success on autism control. DATA SOURCES: Correlation of porin redox activity and expression of autism is based on extensive literature, especially studies of antibodies, identification of cytosolic nicotinamide adenine dinucleotide reduced (NADH) dehydrogenase activity in the VDAC, and evidence for extreme sensitivity of the dehydrogenase to a mercurial. …”
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    Plasma membrane coenzyme Q: evidence for a role in autism
  7. 347
    “…In addition to the XML format, we also provide tools for the calculation of a wide range of quality metrics as well as a database format and interconversion tools, so that existing LIMS systems can easily add relational storage of the quality control data to their existing schema. We here describe the qcML specification, along with possible use cases and an illustrative example of the subsequent analysis possibilities. …”
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    qcML: An Exchange Format for Quality Control Metrics from Mass Spectrometry Experiments
  8. 348
    “…Following this assumption, we investigate the type I error and the power of two proposed collapsing methods (combined multivariate and collapsing method and the functional principal component analysis [FPCA]-based statistic) using the case-control data provided for the Genetic Analysis Workshop 18 with knowledge of the true model. …”
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    A comparison of two collapsing methods in different approaches
  9. 349
    por Turkmen, Asuman S, Lin, Shili
    Publicado 2014
    “…The simulated data is used to investigate whether there is an advantage to using family data compared to case-control data. The results indicate that population-based methods suffer from power loss, especially when the sample size is small. …”
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    Identifying rare variant associations in population-based and family-based designs
  10. 350
    “…We propose new approaches to quality control, data normalisation and batch correction through control-probe adjustment and establish a null hypothesis for EWAS using permutation testing. …”
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    A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies
  11. 351
    “…The PlasmoGEM web interface allows users to search a database of finished knock-out and gene tagging vectors, view details of their designs, download vector sequence in different formats and view available quality control data as well as suggested genotyping strategies. …”
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    PlasmoGEM, a database supporting a community resource for large-scale experimental genetics in malaria parasites
  12. 352
    “…We analyzed data for 24 INPH patients who were presented with typical clinical symptoms (gait disturbance, dementia, and/ or urinary incontinence) and Evans index > 0.3, and compared these with the control data from 21 elderly persons (≥ 60 years). DTI brain images were obtained with a 3T scanner. …”
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    White Matter Characteristics of Idiopathic Normal Pressure Hydrocephalus: A Diffusion Tensor Tract-Based Spatial Statistic Study
  13. 353
    “…The results were compared to control data obtained in our previous study. We found that spinalization affected the distribution of F- and E-neurons across the spinal grey matter, caused a significant decrease in their activity, as well as disturbances in processing of posture-related sensory inputs. …”
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    Effects of acute spinalization on neurons of postural networks
  14. 354
    “…The results suggest that the clustering approach could improve the power of nonparametric tests and that the clustering sum test has the potential to serve as a practical tool when dealing with rare variants with unbalanced case-control data in genome-wide case-control studies.…”
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    A clustering approach to identify rare variants associated with hypertension
  15. 355
    por Luo, Yueqiu, Liu, Siyu, Yao, Ke
    Publicado 2017
    “…Using two different RNA libraries, we sequenced the complete transcriptome of HLE cells treated with miR-184, m-miR-184, and a negative control. Data were integrated in an effort to identify any novel gene affected by m-miR-184. …”
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    Transcriptome-wide Investigation of mRNA/circRNA in miR-184 and Its r.57c > u Mutant Type Treatment of Human Lens Epithelial Cells
  16. 356
    “…A systematic approach for epigenome data and multiple types of transcriptome data is needed to control data quality and to perform cell-to-cell heterogeneity analysis on these ultra-high-dimensional transcriptome and epigenome datasets. …”
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    Dr.seq2: A quality control and analysis pipeline for parallel single cell transcriptome and epigenome data
  17. 357
    “…In this review, we present a practical guide to help researchers design their first scRNA-seq studies, including introductory information on experimental hardware, protocol choice, quality control, data analysis and biological interpretation.…”
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    A practical guide to single-cell RNA-sequencing for biomedical research and clinical applications
  18. 358
    por Yang, Qian, Pan, Jay
    Publicado 2017
    “…METHODS: This paper analyzes the relationship between hospital competition and the probability of medical disputes occurrence according to the theory of social control. Data from all hospitals in the Sichuan province of China from 2011 to 2014 were included in the study. …”
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    Control under times of uncertainty: the relationship between hospital competition and physician-patient disputes
  19. 359
    “…Women enrolled in community cultural centers (n=314) were randomly divided into two educational groups: role playing (intervention) and lecture (control). Data were collected using a structured questionnaire before and after intervention. …”
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    Role Playing for Improving Women’s Knowledge of Breast Cancer Screening and Performance of Breast Self-Examination
  20. 360
    “…We show that the best performing published algorithms either find large numbers of fusions in negative control data or suffer from low sensitivity detecting known driving fusions in gold standard settings, such as EWSR1-FLI1. …”
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    Statistical algorithms improve accuracy of gene fusion detection
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