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  1. 2361
    “…Based on cytological analysis of meiotic DNA double-strand breaks (DSB) and crossovers (COs), we show that Dsbc1 influences DSB and CO, not only at Psmb9, but in several other regions of Chr 17. …”
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    Genome-Wide Control of the Distribution of Meiotic Recombination
  2. 2362
    “…In addition to this specific expression patterns, we found that Lrmp/Jaw1 is associated with type III IP(3) receptor (IP(3)R3) via its coiled-coil domain in the COS7 heterologous expression system. These results raise the possibility that Lrmp/Jaw1 interacts with IP(3)R3 in taste cells and suggest an important role for Lrmp/Jaw1 in the IP(3)-Ca(2+) signal cascade in sweet, bitter, and umami taste signal transduction.…”
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    Lrmp/Jaw1 is Expressed in Sweet, Bitter, and Umami Receptor–Expressing Cells
  3. 2363
    “…AATYK1A bound to the p35 activation subunit of Cdk5 in cultured cells and in mouse brains and colocalized with p35 on endosomes in COS-7 cells. AATYK1A was phosphorylated at Ser34 by Cdk5/p35 in vitro, in cultured neurons and in mouse brain. …”
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    Phosphorylation of AATYK1 by Cdk5 Suppresses Its Tyrosine Phosphorylation
  4. 2364
    por Chafe, Shawn C., Mangroo, Dev
    Publicado 2010
    “…Like exportin-t, overexpression of Scyl1 restored export of a nuclear export-defective serine amber suppressor tRNA mutant in COS-7 cells. Scyl1 binds tRNA saturably, and associates with the nuclear pore complex by interacting, in part, with Nup98. …”
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    Scyl1 Facilitates Nuclear tRNA Export in Mammalian Cells by Acting at the Nuclear Pore Complex
  5. 2365
    “…However, in P. sinensis embryos, the gene hepatocyte growth factor (HGF), encoding a regulatory factor for delamination of the dermomyotomal VLL, was uniquely expressed in sclerotome and the lateral body wall at the interlimb level. Implantation of COS-7 cells expressing a HGF antagonist into the turtle embryo inhibited CR formation. …”
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    Hepatocyte growth factor is crucial for development of the carapace in turtles
  6. 2366
    “…This was challenged with experiments on transfected PC1 in COS1 cells, a non-endocrine cell line2. To address this issue, we undertook to analyze its extraction properties  in vitro and its immunocytochemical localization  in situ in AtT20 cells, an endocrine cell line that expresses PC1. …”
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    Exploring the membrane topology of prohormone convertase 1 in AtT20 Cells: in situ analysis by immunofluorescence microscopy
  7. 2367
    “…We first expressed tagged protamine 1-myc and protamine 2-V5 in HeLa and COS-1 cells and showed by both confocal microscopy and immunoblotting analyses that protamines were produced in vitro and colocalized correctly to the nucleus. …”
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    The nuclear form of glutathione peroxidase 4 colocalizes and directly interacts with protamines in the nuclear matrix during mouse sperm chromatin assembly
  8. 2368
    “…We investigated Ca(2+) signaling, an early event in EGF responses, in response to picomolar doses in COS-7 cells where the monomer/dimer equilibrium is unaltered by the synthesis of exogenous EGFR. …”
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    Physiological Epidermal Growth Factor Concentrations Activate High Affinity Receptors to Elicit Calcium Oscillations
  9. 2369
    “…RESULTS: We have tested the affinity of 121 miRNAs processed from this locus for DLK1 by co-transfecting COS1 cells with a vector expressing the full-length ovine DLK1 with corresponding mimic miRNAs. …”
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    Experimental evaluation does not reveal a direct effect of microRNA from the callipyge locus on DLK1 expression
  10. 2370
    “…Co-precipitation experiments demonstrated that human MORN4 binds to human myosin IIIA (MYO3A). In COS7 cells, MORN4 and MYO3A, but not MORN4 and MYO3B, co-localize to actin rich filopodia extensions. …”
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    Invertebrate and Vertebrate Class III Myosins Interact with MORN Repeat-Containing Adaptor Proteins
  11. 2371
    “…Atomic force micrographs show an increase in surface roughness from 0.5 to 4.3 nm for the pristine sample and the sample irradiated at 60° incidence angle due to cos(−1)(θ) dependence on sputtering yield. With increase in angle of incidence, there is transition observed from nanodots to aligned nanodots perpendicular to the direction of the beam. …”
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    Investigations of ripple pattern formation on Germanium surfaces using 100-keV Ar(+) ions
  12. 2372
    “…The ability of acrolein-modified HDL (acro-HDL) to serve as an acceptor of free cholesterol (FC) from COS-7 cells transiently expressing SR-BI was significantly decreased. …”
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    Acrolein Impairs the Cholesterol Transport Functions of High Density Lipoproteins
  13. 2373
    “…Here we present the CRISPR/Cas9 target online predictor (CCTop, http://crispr.cos.uni-heidelberg.de) to overcome limitations of already available tools. …”
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    CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool
  14. 2374
    “…With Floquet theorem and numerical analysis we reveal that from the resonant driving frequency for coherent Rabi oscillation one can directly map out the FJR cos(πΦ/Φ(0)) as a signature of MBSs, with Φ the magnetic flux through SQUID and Φ(0) = hc/2e the flux quantum. …”
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    Viewing Majorana Bound States by Rabi Oscillations
  15. 2375
    “…The Medaka Expression Pattern Database (MEPD; http://mepd.cos.uni-heidelberg.de/) is designed as a repository of medaka expression data for the scientific community. …”
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    MEPD: medaka expression pattern database, genes and more
  16. 2376
    “…Here we found that FC101 induced cell death in COS7 and HEK293 cells in part by activating JNK pathway. …”
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    Fusarochromanone-induced reactive oxygen species results in activation of JNK cascade and cell death by inhibiting protein phosphatases 2A and 5
  17. 2377
    “…Here we discover that microtubule-associated lipid droplets (LDs) in COS1 cells respond to an optical trap with a remarkable enhancement in sustained force production. …”
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    Load-induced enhancement of Dynein force production by LIS1–NudE in vivo and in vitro
  18. 2378
    por Wang, Liang, Cooper, Jonathan A.
    Publicado 2017
    “…The high spatiotemporal resolution of the opto-Dab1 probe also allows us to control membrane protrusion, retraction and ruffling by local illumination in both COS7 cells and in primary neurons. This shows that Dab1 activation is sufficient to orient cell movement in the absence of other signals. …”
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    Optogenetic control of the Dab1 signaling pathway
  19. 2379
    “…Evidence for a function of ODCrp was found in ODC assays on lysates from transfected Cos-7 cells where ODCrp repressed the activity of endogenous ODC while Cys(363)Ala mutated ODCrp increased the enzymatic activity of endogenous ODC.…”
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    Characterization of an androgen-responsive, ornithine decarboxylase-related protein in mouse kidney
  20. 2380
    “…We found that new spacers are acquired immediately following infection preferentially from the cos site, the viral free DNA end that is first injected into the cell. …”
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    CRISPR-Cas systems exploit viral DNA injection to establish and maintain adaptive immunity
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