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  1. 2561
    “…Meiotic crossovers (COs) generate genetic diversity and are critical for the correct completion of meiosis in most species. …”
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    AAA-ATPase FIDGETIN-LIKE 1 and Helicase FANCM Antagonize Meiotic Crossovers by Distinct Mechanisms
  2. 2562
    “…Based on in silico analysis, luciferase reporter gene assays and gel shift assays were performed using COS-7, HepG2, C2C12, and 3T3-L1 cells. Deletion mapping of the 5´ flanking region (-1324 to +33) of ADRB2 revealed the region between -307 and -269 to be the minimal promoter, including regulatory elements essential for the basal transcriptional activity in all four tested cell types. …”
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    Identification and Functional Characterization of Cis-Regulatory Elements Controlling Expression of the Porcine ADRB2 Gene
  3. 2563
    por Baldwin, Graham S., Sims, Ioulia
    Publicado 2015
    “…Binding of gastrin(17), gastrin(17)SO(4) and gastrin(17)PO(4) to the human CCK1 and CCK2 receptors was assessed by competition with [(125)I]-Bolton and Hunter-labelled cholecystokinin(8) in transiently transfected COS cells. Tyrosine sulphation or phosphorylation increased the affinity of gastrin(17) for the first ferric ion bound from 267 to 83 pM and 14 pM, respectively, but had no effect on the stoichiometry of ferric ion binding. …”
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    Tyrosine modification increases the affinity of gastrin for ferric ions
  4. 2564
    “…Two inbred lines, Cream of Saskatchewan (COS) and LSW-177 had been re-sequenced and analyzed by Perl self-compiled script for CAPS marker development. 88.7% and 78.5% of the assembled sequences of the two parental materials could map to the reference watermelon genome, respectively. …”
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    Development of cleaved amplified polymorphic sequence markers and a CAPS-based genetic linkage map in watermelon (Citrullus lanatus [Thunb.] Matsum. and Nakai) constructed using whole-genome re-sequencing data
  5. 2565
    “…Co-expression of a single guide RNA plasmid, a FokI-dCas9-zsGreen1 plasmid, and the presence of a single-stranded oligodeoxynucleotide in PAH_c.1222C>T COS-7 cells – an in vitro model for PKU – corrected the PAH variant and restored PAH activity. …”
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    CRISPR RNA-guided FokI nucleases repair a PAH variant in a phenylketonuria model
  6. 2566
    “…Finally, we provide evidence that Cos2 is also sumoylated, which counteracts its inhibitory role on Smo accumulation in the wing. …”
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    SUMO regulates the activity of Smoothened and Costal-2 in Drosophila Hedgehog signaling
  7. 2567
    “…Three cos-type virulent Streptococcus thermophilus phages were isolated from failed mozzarella production in Uruguay. …”
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    Phage-host interactions in Streptococcus thermophilus: Genome analysis of phages isolated in Uruguay and ectopic spacer acquisition in CRISPR array
  8. 2568
    “…Then, the interaction between overexpressed MAGE-G1 and FSCN1 or VIME was validated by GST-pull down assay in bacteria and by co-immunoprecipitation assay in COS7 cells. Endogenous co-immunoprecipitation assay further confirmed that MAGE-G1 interacted with FSCN1 or VIME in P19 cells after a 6-day retinoic acid-induced neuronal differentiation. …”
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    Identification of Novel MAGE-G1-Interacting Partners in Retinoic Acid-Induced P19 Neuronal Differentiation Using SILAC-Based Proteomics
  9. 2569
    “…The pathways conserved across lines and at all three time points postinfection included iCOS-iCOSL signaling in T helper cells, NF-κB signaling, the role of nuclear factor of activated T cells in the regulation of the immune response, calcium-induced T lymphocyte apoptosis, phospholipase C signaling, and CD28 signaling in T helper cells. …”
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    Novel Mechanisms Revealed in the Trachea Transcriptome of Resistant and Susceptible Chicken Lines following Infection with Newcastle Disease Virus
  10. 2570
    “…Enzymatic removal of 5′-triphosphates allowed identifying those cosRNA that mark a transcription start site. We detected another class of sRNAs derived from low abundance transcripts, antisense to mRNAs. …”
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    Small RNA profiling in Chlamydomonas: insights into chloroplast RNA metabolism
  11. 2571
    “…Here we demonstrate that Cordon-Bleu (Cobl)–like, an uncharacterized protein suggested to represent a very distantly related, evolutionary ancestor of the actin nucleator Cobl, despite having only a single G-actin–binding Wiskott–Aldrich syndrome protein Homology 2 (WH2) domain, massively promoted the formation of F-actin–rich membrane ruffles of COS-7 cells and of dendritic branches of neurons. …”
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    Cobl-like promotes actin filament formation and dendritic branching using only a single WH2 domain
  12. 2572
    “…Different types of antenna with cos(n)-like radiation patterns as lens illuminators are analyzed on the vertical plane of the flat lenses to have a high efficiency over the considered operating band. …”
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    Towards Millimeter-wavelength: Transmission-Mode Fresnel-Zone Plate Lens Antennas using Plastic Material Porosity Control in Homogeneous Medium
  13. 2573
    “…METHOD: TBEV structural gene constructs of a Swedish Torö strain were cloned into plasmids driven by the promoters CAG and CMV and then transfected into various cell lines, including COS-1 and BHK-21. Time-course sampling of the cells, culture fluid, cell lysate supernatant, and pellet specimens were performed. …”
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    Investigating Tick-borne Flaviviral-like Particles as a Delivery System for Gene Therapy
  14. 2574
    “…These derivatised films supported activation of DDR2 expressed in either COS-7 or HEK293 cells, reflected by phosphorylation of tyrosine 740, and VWF-mediated platelet deposition from flowing blood was restored. …”
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    Coupling of a specific photoreactive triple-helical peptide to crosslinked collagen films restores binding and activation of DDR2 and VWF
  15. 2575
    “…To assess the transfection efficiency mediated by EPAE and EPAE-FA polymers, we performed in vitro transfection activity assays using FR-negative (COS-7) and FR-positive (HeLa) cells. The EPAE-FA12k/DNA and EPAE-FA14k/DNA complexes were able to transfect HeLa cell in vitro with higher transfection efficiency than PEI25k/DNA at the similar weight ratio. …”
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    Synthesis and Characterization of Cationic Glycidyl-Based Poly(aminoester)-Folic Acid Targeting Conjugates and Study on Gene Delivery
  16. 2576
    “…All extracts were also tested for their cytotoxicity in COS7 cells and none of the most active extracts was cytotoxic at the concentrations which inhibit AChE. …”
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    Extracts from Traditional Chinese Medicinal Plants Inhibit Acetylcholinesterase, a Known Alzheimer’s Disease Target
  17. 2577
    “…Methods: A prospective matched cohort survey study using the questionnaire ‘Consequences of Screening for Breast Cancer’ (COS-BC), which was translated from Danish to Norwegian. …”
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    Psychosocial consequences among women with false-positive results after mammography screening in Norway
  18. 2578
    “…Co-expression of Gas5 with either MR or GR in COS-7 cells confirmed previous findings showing that it decreases receptor-mediated transactivation. …”
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    SAT-007 The Long Non-coding RNA Gas5 Selectively Regulates Corticosteroid Receptor Activity
  19. 2579
    “…One of these four measures is the phase shift ϕ in a sinusoid of the form x(t) = A(cos(ωt + ϕ), where t is time. The other measures arise by creating a replica of the periodic process x(t) called the Hilbert transform x̃(t), which is 90 degrees out of phase with the original process x(t). …”
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    What is Phase in Cellular Clocks?
  20. 2580
    “…The recombinant plasmids were transfected into COS-7 cells to observe the co-localization by confocal laser scanning microscopy. …”
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    Identification of whirlin domains interacting with espin: A study of the mechanism of Usher syndrome type II
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