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2741por Han, Sangbin, Lee, Jong Hwan, Kim, Gaabsoo, Ko, Justin Sangwook, Choi, Soo Joo, Kwon, Ji Hae, Heo, Burn Young, Gwak, Mi Sook“…METHODS: Nineteen recipients undergoing adult-to-adult living donor liver transplantation were enrolled in this prospective observational study. COs were recorded automatically by the two devices and compared simultaneously at 3-minute intervals. …”
Publicado 2015
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2742por Vuistiner, Philippe, Rousson, Valentin, Henry, Hugues, Lescuyer, Pierre, Boulat, Olivier, Gaspoz, Jean-Michel, Mooser, Vincent, Vollenweider, Peter, Waeber, Gerard, Cornuz, Jacques, Paccaud, Fred, Bochud, Murielle, Guessous, Idris“…The best model included gender, BMI, and sin-cos functions of measurement day. Sex- and BMI-specific 25(OH)D centile curves as a function of measurement date were generated. …”
Publicado 2015
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2743por Yokoi, Setsuri, Ishihara, Naoko, Miya, Fuyuki, Tsutsumi, Makiko, Yanagihara, Itaru, Fujita, Naoko, Yamamoto, Hiroyuki, Kato, Mitsuhiro, Okamoto, Nobuhiko, Tsunoda, Tatsuhiko, Yamasaki, Mami, Kanemura, Yonehiro, Kosaki, Kenjiro, Kojima, Seiji, Saitoh, Shinji, Kurahashi, Hiroki, Natsume, Jun“…To elucidate how the various TUBA1A mutations affect the severity of the phenotype, we examined the capacity of the mutant protein to incorporate into the endogenous microtubule network in transfected COS7 cells by measuring line density using line extraction in an immunofluorescence study. …”
Publicado 2015
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2744por Alshahrani, Saeed, Almutairi, Mohammed Mashari, Kursan, Shams, Dias-Junior, Eduardo, Almiahuob, Mohamed Mahmoud, Aguilar-Bryan, Lydia, Di Fulvio, Mauricio“…This has been confirmed by using chronic pharmacological down-regulation of NKCC1 with bumetanide in the mouse MIN6 β-cell line or permanent molecular silencing of NKCC1 in COS7 cells, which results in increased NKCC2 expression. …”
Publicado 2015
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2745“…Nevertheless, LPD is a very common condition that may occur during a series of clinical conditions, and during controlled ovarian stimulation (COS) and hyperstimulation (COH) programs. In many cases, the correct approach to treat LPD is the identification and correction of any underlying condition while, in case of no underlying dysfunction, the treatment becomes empiric. …”
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2746por Ochiishi, Tomoyo, Doi, Motomichi, Yamasaki, Kazuhiko, Hirose, Keiko, Kitamura, Akira, Urabe, Takao, Hattori, Nobutaka, Kinjo, Masataka, Ebihara, Tatsuhiko, Shimura, Hideki“…We found that Aβ-GFP fusion proteins induced cell death in COS7 cells. These results suggested that novel Aβ-GFP fusion proteins could be utilized for studying the physiological functions of Aβ oligomers in living cells and animals, and for drug screening by analyzing Aβ toxicity.…”
Publicado 2016
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2747por Hong, Ye, Sonneville, Remi, Agostinho, Ana, Meier, Bettina, Wang, Bin, Blow, J. Julian, Gartner, Anton“…Meiotic recombination is essential for the repair of programmed double strand breaks (DSBs) to generate crossovers (COs) during meiosis. The efficient processing of meiotic recombination intermediates not only needs various resolvases but also requires proper meiotic chromosome structure. …”
Publicado 2016
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2748“…Overexpression of the STAR p.N148K mutant in nonsteroidogenic COS-1 cells supplemented with an electron transport system showed activity similar to the background level, which was ∼10% of that observed with wild-type (WT) STAR. …”
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2749por Klaus, Miriam, Prokoph, Nina, Girbig, Mathias, Wang, Xuecong, Huang, Yong-Heng, Srivastava, Yogesh, Hou, Linlin, Narasimhan, Kamesh, Kolatkar, Prasanna R., Francois, Mathias, Jauch, Ralf“…This SOX decoy also interfered with the expression of a luciferase reporter under control of a SOX18-dependent VCAM1 promoter in COS7 cells. Collectively, we propose SOX decoys as potential strategy for inhibiting SOX18 activity to disrupt tumour-induced neo-lymphangiogenesis.…”
Publicado 2016
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2750“…The iutA gene expression in genetic cassette of pVax/iutA was evaluated in COS7 cell line by RT-PCR. Then, injected to mouse model, which divided to three groups: injected with pVax vector, PBS and pVax/iutA cassette respectively in two stages (d 1 and 14). …”
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2751por Harris, Elizabeth, Bladen, Catherine L., Mayhew, Anna, James, Meredith, Bettinson, Karen, Moore, Ursula, Smith, Fiona E., Rufibach, Laura, Cnaan, Avital, Bharucha-Goebel, Diana X., Blamire, Andrew M., Bravver, Elena, Carlier, Pierre G., Day, John W., Díaz-Manera, Jordi, Eagle, Michelle, Grieben, Ulrike, Harms, Matthew, Jones, Kristi J., Lochmüller, Hanns, Mendell, Jerry R., Mori-Yoshimura, Madoka, Paradas, Carmen, Pegoraro, Elena, Pestronk, Alan, Salort-Campana, Emmanuelle, Schreiber-Katz, Olivia, Semplicini, Claudio, Spuler, Simone, Stojkovic, Tanya, Straub, Volker, Takeda, Shin'ich, Rocha, Carolina Tesi, Walter, M.C., Bushby, Kate“…METHODS: The Clinical Outcome Study for dysferlinopathy (COS) is an international multicenter study of this disease, evaluating patients with genetically confirmed dysferlinopathy over 3 years. …”
Publicado 2016
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2752Quantitative and combinatory determination of in situ phosphorylation of tau and its FTDP-17 mutantspor Kimura, Taeko, Hosokawa, Tomohisa, Taoka, Masato, Tsutsumi, Koji, Ando, Kanae, Ishiguro, Koichi, Hosokawa, Masato, Hasegawa, Masato, Hisanaga, Shin-ichi“…Tau exhibited ~12 phosphorylation isotypes in COS-7 cells with different combinations of phosphorylation at Thr181, Ser202, Thr231, Ser235 and Ser404. …”
Publicado 2016
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2753por Louw-du Toit, Renate, Perkins, Meghan S., Snoep, Jacky L., Storbeck, Karl-Heinz, Africander, Donita“…Subsequent assays performed in COS-1 cells expressing human 3βHSD2, suggest that these progestins modulate the biosynthesis of steroid hormones by inhibiting the activity of 3βHSD2. …”
Publicado 2016
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2754por Kadri, Naveen Kumar, Harland, Chad, Faux, Pierre, Cambisano, Nadine, Karim, Latifa, Coppieters, Wouter, Fritz, Sébastien, Mullaart, Erik, Baurain, Denis, Boichard, Didier, Spelman, Richard, Charlier, Carole, Georges, Michel, Druet, Tom“…We identify 2,395,177 crossover (CO) events in 94,516 male gametes, and 579,996 CO events in 25,332 female gametes. The average number of COs was found to be larger in males (23.3) than in females (21.4). …”
Publicado 2016
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2755por Gashi, Zafer, Elezaj, Shkelzen, Zeqiraj, Afrim, Grabanica, Driton, Shabani, Isak, Gruda, Bujar, Gashi, Fitore“…CONCLUSIONS: FSH receptor polymorphism is associated with different ovarian response to controlled ovarian stimulation (COS), but is not an important factor in increasing the degree of pregnancy. …”
Publicado 2016
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2756“…Efficient recombination was observed in all cell types tested (a T-cell line, NIH3T3, Cos7, murine ES cells, and primary splenocytes), and did not require localization of the enzyme to the nucleus. …”
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2757“…WGS, de novo assembly, and annotation of the genome revealed a chromosome of 1,718,974 bp and a mega-plasmid (pCOS502) of 125,964 bp. GC content of the genome was 31.2% with 1931 coding sequences and 53 non-coding RNAs. …”
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2758por Ghezzi, Chiara, Calmettes, Guillaume, Morand, Pauline, Ribalet, Bernard, John, Scott“…Activity was assessed in parallel using a FRET glucose sensor. In COS cells and HEK cells, SGLT1 was distributed between the plasma membrane and intracellular compartments, but there was little expression in CHO cells. …”
Publicado 2017
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2759“…Co-expression of both PARN and PLD2 mimicked this pattern in non-cancerous cells (COS-7 fibroblasts) but, surprisingly, not in breast cancer MCF-7 cells, where PARN switches from inhibition to activation of PLD2 gene and protein expression. …”
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2760por Sanders, Matthew A., Zhang, Huamei, Mladenovic, Ljiljana, Tseng, Yan Yuan, Granneman, James G.“…Two highly conserved ABHD5 amino acids (R299 and G328) enabled ABHD4 (ABHD4 N303R/S332G) to activate ATGL in Cos7 cells, brown adipocytes, and artificial lipid droplets. …”
Publicado 2017
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