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3301“…HOW TO CITE THIS ARTICLE: Barboza CL, Valete COS, da Silva ARA. Bundle Adherence of Intravenous Antibiotic Fluid Resuscitation and Vasopressor in Children with Severe Sepsis or Septic Shock. …”
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3302por Morín, Matias, Borreguero, Lucía, Booth, Kevin T, Lachgar, María, Huygen, Patrick, Villamar, Manuela, Mayo, Fernando, Barrio, Luis Carlos, Santos Serrão de Castro, Luciana, Morales, Carmelo, del Castillo, Ignacio, Arellano, Beatriz, Tellería, Dolores, Smith, Richard J. H., Azaiez, Hela, Moreno Pelayo, M. A.“…Transient expression of the c-myc-tagged EYA4 mutants in mammalian COS7 cells revealed absence of expression of the p.S534* mutant, consistent with a model of haploinsufficiency reported for all previously described EYA4 truncating mutations. …”
Publicado 2020
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3303por Kavarthapu, Raghuveer, Anbazhagan, Rajakumar, Sharma, Ashish K., Shiloach, Joseph, Dufau, Maria L.“…This mutation upon expression in COS-1 cells revealed absence of the 61 kDa phosphorylated GRTH in cytoplasm and the presence of the 56 kDa non-phosphorylated GRTH in the nucleus. …”
Publicado 2020
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3304por Wang, Ting, Du, Huihui, Ma, Jingsong, Shen, Lu, Wei, Muyun, Zhao, Xianglong, Chen, Luan, Li, Mo, Li, Guorong, Xing, Qinghe, He, Lin, Qin, Shengying“…METHODS: To investigate whether genetic variants identified in the CYP2E1 coding region affect enzyme function, the enzymes of four single nucleotide polymorphism (SNP) variants in the coding region (novel c.1009C>T, causing p.Arg337X, where X represents the translational stop codon; c.227G>A, causing p.Arg76His; c.517G>A, yielding p.Gly173Ser; and c.1263C>T, presenting the highest allele frequency), two novel alleles (c.[227G>A;1263C>T] and c.[517G>A;1263C>T]), and the wild-type CYP2E1 were heterologously expressed in COS-7 cells and functionally characterized in terms of expression level and chlorzoxazone 6-hydroxylation activity. …”
Publicado 2020
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3305por Song, Wei, Wang, Hao, Lu, Minmin, Ni, Xinxin, Bahri, Nacef, Zhu, Shuihao, Chen, Limin, Wu, Yuehong, Qiu, Jieqiong, Fletcher, Jonathan A., Ou, Wen-Bin“…Likewise, induced AXL inhibited expression of wild type p53 in COS-7 cells and 293T cells. Immunofluorescence staining showed nuclear colocalization of AXL and p53; however, association of AXL and p53 was not demonstrated in immunoprecipitation complexes. …”
Publicado 2020
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3306por Vyas, Nikunj M, Hou, Cindy, Levin, Todd P, Fussa, Mark, DeRose, Joseph, Condoluci, Mark, Williams, James, Ghayad, Zeina, Barnish, Michael, Ali, Shereef N, Kerr, Kathryn H, Scheiblein, Scott W, Fryckberg, Anthony J, Chauhan, Gauri“…No differences were observed in early vs late TCZ therapy on inpatient mortality, but there was a trend toward lower mortality with early TCZ. COS Review of Tocilizumab Patients [Image: see text] CONCLUSION: TCZ is an effective treatment option in patients with SARS-CoV-2 patients at risk of CRS. …”
Publicado 2020
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3307“…Transactivation assays, using COS7 cell line transfected with tilapia SST-Rs together with the reporter plasmid CRE-luc, demonstrated an effect through the cAMP/PKA pathway. …”
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3308por Salama, Sameh, Sharaf, Marwa, Salem, Sondos M., Rasheed, Mazen Abdel, Salama, Ehab, Elnahas, Tamer, Lotfy, Rehab“…Several biomarkers of the ovarian reserve, including follicle stimulating hormone (FSH), anti Müllerian hormone (AMH), have been proposed as possible predictors for the response to controlled ovarian stimulation (COS). Although there are assumptions indicating that the relationship between age and ovarian reserve is highly variable and the potential different validity of ovarian reserve markers in women in different age groups remains to be demonstrated. …”
Publicado 2021
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3309por Liu, Wei, Han, Ying, Xin, Xin, Chen, Liqing, Liu, Yanhong, Liu, Chao, Zhang, Xintong, Jin, Mingji, Jin, Jingzhe, Gao, Zhonggao, Huang, Wei“…The GCA-NPs thus prepared showed prolonged intestinal retention time and good GIT stability due to the presence of chitosan oligosaccharide (COS) and enhanced active transportation via intestinal apical sodium-dependent bile acid transporter (ASBT) due to the presence of GCA. …”
Publicado 2022
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3310“…METHODS: We engineered nonsteroidogenic monkey kidney COS1 cells to express CYP11A1 upon doxycycline induction and examined the mitochondrial structure of these cells. …”
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3311“…BACKGROUND: There is a lack of information on changes in hospital admission rates for childhood-onset schizophrenia (COS), or on patient characteristics, to inform clinical research and health service provision. …”
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3312por Sun, Longjie, Lv, Zheng, Chen, Xuexue, Wang, Chaofan, Lv, Pengbo, Yan, Lu, Tian, Shuang, Xie, Xiaomei, Yao, Xiaohong, Liu, Jingjing, Wang, Zhao, Luo, Haoshu, Cui, Sheng, Liu, Jiali“…Immunofluorescence analyses suggest that failed synapsis and an inability to undergo recombination result in fewer homologous DNA crossovers (COs) in the Srsf1 cKO mouse ovaries. Moreover, SRSF1 directly binds and regulates the expression of the POI-related genes Six6os1 and Msh5 via AS to implement the meiotic prophase I program. …”
Publicado 2023
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3313por Abdallah, J., Abreu, P., Adam, W., Adzic, P., Albrecht, T., Alemany-Fernandez, R., Allmendinger, T., Allport, P.P., Amaldi, U., Amapane, N., Amato, S., Anashkin, E., Andreazza, A., Andringa, S., Anjos, N., Antilogus, P., Apel, W-D., Arnoud, Y., Ask, S., Asman, B., Augustin, J.E., Augustinus, A., Baillon, P., Ballestrero, A., Bambade, P., Barbier, R., Bardin, D., Barker, G.J., Baroncelli, A., Battaglia, M., Baubillier, M., Becks, K-H., Begalli, M., Behrmann, A., Ben-Haim, E., Benekos, N., Benvenuti, A., Berat, C., Berggren, M., Bertrand, D., Besancon, M., Besson, N., Bloch, D., Blom, M., Bluj, M., Bonesini, M., Boonekamp, M., Booth, P.S.L., Borisov, G., Botner, O., Bouquet, B., Bowcock, T.J.V., Boyko, I., Bracko, M., Brenner, R., Brodet, E., Bruckman, P., Brunet, J.M., Buschbeck, B., Buschmann, P., Calvi, M., Camporesi, T., Canale, V., Carena, F., Castro, N., Cavallo, F., Chapkin, M., Charpentier, Ph., Checchia, P., Chierici, R., Chliapnikov, P., Chudoba, J., Chung, S.U., Cieslik, K., Collins, P., Contri, R., Cosme, G., Cossutti, F., Costa, M.J., Crennell, D., Cuevas, J., D'Hondt, J., da Silva, T., Da Silva, W., Della Ricca, G., De Angelis, A., De Boer, W., De Clercq, C., De Lotto, B., De Maria, N., De Min, A., de Paula, L., Di Ciaccio, L., Di Simone, A., Doroba, K., Drees, J., Eigen, G., Ekelof, T., Ellert, M., Elsing, M., Espirito Santo, M.C., Fanourakis, G., Fassouliotis, D., Feindt, M., Fernandez, J., Ferrer, A., Ferro, F., Flagmeyer, U., Foeth, H., Fokitis, E., Fulda-Quenzer, F., Fuster, J., Gandelman, M., Garcia, C., Gavillet, Ph., Gazis, E., Gokieli, R., Golob, B., Gomez-Ceballos, G., Goncalves, P., Graziani, E., Grosdidier, G., Grzelak, K., Guy, J., Haag, C., Hallgren, A., Hamacher, K., Hamilton, K., Haug, S., Hauler, F., Hedberg, V., Hennecke, M., Hoffman, J., Holmgren, S-O., Holt, P.J., Houlden, M.A., Jackson, J.N., Jarlskog, G., Jarry, P., Jeans, D., Johansson, E.K., Jonsson, P., Joram, C., Jungermann, L., Kapusta, F., Katsanevas, S., Katsoufis, E., Kernel, G., Kersevan, B.P., Kerzel, U., King, B.T., Kjaer, N.J., Kluit, P., Kokkinias, P., Kourkoumelis, C., Kouznetsov, O., Krumstein, Z., Kucharczyk, M., Lamsa, J., Leder, G., Ledroit, F., Leinonen, L., Leitner, R., Lemonne, J., Lepeltier, V., Lesiak, T., Liebig, W., Liko, D., Lipniacka, A., Lopes, J.H., Lopez, J.M., Loukas, D., Lutz, P., Lyons, L., MacNaughton, J., Malek, A., Maltezos, S., Mandl, F., Marco, J., Marco, R., Marechal, B., Margoni, M., Marin, J-C., Mariotti, C., Markou, A., Martinez-Rivero, C., Masik, J., Mastroyiannopoulos, N., Matorras, F., Matteuzzi, C., Mazzucato, F., Mazzucato, M., Mc Nulty, R., Meroni, C., Migliore, E., Mitaroff, W., Mjoernmark, U., Moa, T., Moch, M., Monig, Klaus, Monge, R., Montenegro, J., Moraes, D., Moreno, S., Morettini, P., Mueller, U., Muenich, K., Mulders, M., Mundim, L., Murray, W., Muryn, B., Myatt, G., Myklebust, T., Nassiakou, M., Navarria, F., Nawrocki, K., Nemecek, S., Nicolaidou, R., Nikolenko, M., Oblakowska-Mucha, A., Obraztsov, V., Olshevski, A., Onofre, A., Orava, R., Osterberg, K., Ouraou, A., Oyanguren, A., Paganoni, M., Paiano, S., Palacios, J.P., Palka, H., Papadopoulou, Th.D., Pape, L., Parkes, C., Parodi, F., Parzefall, U., Passeri, A., Passon, O., Peralta, L., Perepelitsa, V., Perrotta, A., Petrolini, A., Piedra, J., Pieri, L., Pierre, F., Pimenta, M., Piotto, E., Podobnik, T., Poireau, V., Pol, M.E., Polok, G., Pozdniakov, V., Pukhaeva, N., Pullia, A., Radojicic, D., Rebecchi, P., Rehn, J., Reid, D., Reinhardt, R., Renton, P., Richard, F., Ridky, J., Rivero, M., Rodriguez, D., Romero, A., Ronchese, P., Roudeau, P., Rovelli, T., Ruhlmann-Kleider, V., Ryabtchikov, D., Sadovsky, A., Salmi, L., Salt, J., Sander, C., Savoy-Navarro, A., Schwickerath, U., Sekulin, R., Siebel, M., Sisakian, A., Smadja, G., Smirnova, O., Sokolov, A., Sopczak, A., Sosnowski, R., Spassov, T., Stanitzki, M., Stocchi, A., Strauss, J., Stugu, B., Szczekowski, M., Szeptycka, M., Szumlak, T., Tabarelli, T., Tegenfeldt, F., Timmermans, J., Tkatchev, L., Tobin, M., Todorovova, S., Tome, B., Tonazzo, A., Tortosa, P., Travnicek, P., Treille, D., Tristram, G., Trochimczuk, M., Troncon, C., Turluer, M-L., Tyapkin, I.A., Tyapkin, P., Tzamarias, S., Uvarov, V., Valenti, G., Van Dam, P., Van Eldik, J., van Remortel, N., Van Vulpen, I., Vegni, G., Veloso, F., Venus, W., Verdier, P., Verzi, V., Vilanova, D., Vitale, L., Vrba, V., Wahlen, H., Washbrook, A.J., Weiser, C., Wicke, D., Wickens, J., Wilkinson, G., Winter, M., Witek, M., Yushchenko, O., Zalewska, A., Zalewski, P., Zavrtanik, D., Zhuravlov, V., Zimine, N.I., Zintchenko, A., Zupan, M.“…The two-particle joint polarisation probabilities, i.e. the spin density matrix elements rho_TT, rho_LT, rho_LL, are measured as functions of the W- production angle, theta_W-, at an average reaction energy of 198.2 GeV. Averaged over all cos(theta_W-), the following joint probabilities are obtained: rho_TT = (67 +/- 8)%, rho_LT = (30 +/- 8)%, rho_LL = (3 +/- 7)% . …”
Publicado 2009
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3314por Hu, Yuepeng, Zhang, Guofu, Yang, Qi, Pu, Na, Li, Kaiwei, Li, Baiqiang, Cooper, David N., Tong, Zhihui, Li, Weiqin, Chen, Jian-Min“…The functional consequences of the LPL missense variant of interest were characterized by in vitro expression in HEK-293T and COS-7 cells followed by Western blot and LPL activity assays. …”
Publicado 2023
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3315por Pearce, Gemma, Holliday, Nikki, Sandhu, Harbinder, Eftekhari, Helen, Bruce, Julie, Timms, Emma, Ablett, Laura, Kavi, Lesley, Simmonds, Jane, Evans, Rebecca, Magee, Paul, Powell, Richard, Keogh, Shane, McGregor, Gordon“…METHODS: The intervention and feasibility trial design were co-created as part of the PostUraL tachycardia Syndrome Exercise (PULSE) study. We used the ‘three co’s framework’ of co-define, co-design and co-refine. …”
Publicado 2023
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3316por Cardoso, João CR, de Vet, Edwin CJM, Louro, Bruno, Elgar, Greg, Clark, Melody S, Power, Deborah M“…Functional analysis of the paralogue sbPAC(1)s in Cos7 cells revealed that they are strongly stimulated in the presence of mammalian PACAP(27 )and PACAP(38 )and far less with VIP (Vasoactive Intestinal Peptide). …”
Publicado 2007
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3317por Vaughn, Samuel E., Foley, Corinne, Lu, Xiaoming, Patel, Zubin H., Zoller, Erin E., Magnusen, Albert F., Williams, Adrienne H., Ziegler, Julie T., Comeau, Mary E., Marion, Miranda C., Glenn, Stuart B., Adler, Adam, Shen, Nan, Nath, Swapan, Stevens, Anne M., Freedman, Barry I., Tsao, Betty P., Jacob, Chaim O., Kamen, Diane L., Brown, Elizabeth E., Gilkeson, Gary S., Alarcón, Graciela S., Reveille, John D., Anaya, Juan-Manuel, James, Judith A., Moser, Kathy L., Criswell, Lindsey A., Vilá, Luis M., Alarcón-Riquelme, Marta E., Petri, Michelle, Scofield, R. Hal, Kimberly, Robert P., Ramsey-Goldman, Rosalind, Binjoo, Young, Choi, Jeongim, Bae, Sang-Cheol, Boackle, Susan A., Vyse, Timothy J., Guthridge, Joel M., Namjou, Bahram, Gaffney, Patrick M., Langefeld, Carl D., Kaufman, Kenneth M., Kelly, Jennifer A., Harley, Isaac T. W., Harley, John B., Kottyan, Leah C.“…While PXK is involved in trafficking of epidermal growth factor Receptor (EGFR) in COS-7 cells, mechanisms linking PXK to lupus pathophysiology have remained undefined. …”
Publicado 2015
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3318por Huang, Yong, Ma, Shwu-Fan, Vij, Rekha, Oldham, Justin M., Herazo-Maya, Jose, Broderick, Steven M., Strek, Mary E., White, Steven R., Hogarth, D. Kyle, Sandbo, Nathan K., Lussier, Yves A., Gibson, Kevin F., Kaminski, Naftali, Garcia, Joe G. N., Noth, Imre“…Functional pathway analysis revealed that the canonical pathways enriched with the IPF prognostic predictor gene set were involved in T-cell biology, including iCOS, T-cell receptor, and CD28 signaling. CONCLUSIONS: Using supervised and unsupervised analyses, we identified a set of IPF prognostic predictor genes and derived a functional genomic model that predicted high and low-risk IPF patients with high accuracy. …”
Publicado 2015
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3319por Zhou, Li-Juan, Chen, Min, Puthiyakunnon, Santhosh, He, Cheng, Xia, Jing, He, Cynthia Y., Deng, Sheng-Qun, Peng, Hong-Juan“…It was further identified that TgROP18 interacted with P2X1, and overexpression of ROP18 in COS7 cells significantly inhibited cell apoptosis mediated by P2X1. …”
Publicado 2019
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3320por Pugliese, Michael, Tingley, Kylie, Chow, Andrea, Pallone, Nicole, Smith, Maureen, Rahman, Alvi, Chakraborty, Pranesh, Geraghty, Michael T., Irwin, Julie, Tessier, Laure, Nicholls, Stuart G., Offringa, Martin, Butcher, Nancy J., Iverson, Ryan, Clifford, Tammy J., Stockler, Sylvia, Hutton, Brian, Paik, Karen, Tao, Jessica, Skidmore, Becky, Coyle, Doug, Duddy, Kathleen, Dyack, Sarah, Greenberg, Cheryl R., Ghai, Shailly Jain, Karp, Natalya, Korngut, Lawrence, Kronick, Jonathan, MacKenzie, Alex, MacKenzie, Jennifer, Maranda, Bruno, Mitchell, John J., Potter, Murray, Prasad, Chitra, Schulze, Andreas, Sparkes, Rebecca, Taljaard, Monica, Trakadis, Yannis, Walia, Jagdeep, Potter, Beth K.“…Informed by an established framework and a previously published pediatric COS, outcomes were grouped into five, mutually-exclusive, a priori core areas: growth and development, life impact, pathophysiological manifestations, resource use, and death. …”
Publicado 2020
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