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  1. 1301
    “…During meiotic prophase I, double-strand breaks (DSBs) initiate homologous recombination leading to non-crossovers (NCOs) and crossovers (COs). In mouse, 10% of DSBs are designated to become COs, primarily through a pathway dependent on the MLH1-MLH3 heterodimer (MutLγ). …”
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    A mutation in the endonuclease domain of mouse MLH3 reveals novel roles for MutLγ during crossover formation in meiotic prophase I
  2. 1302
    “…It was interesting when the COs increased from 0.3 to 0.5; the cardiac volumes increased while the EF decreased. …”
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    The correlation between myocardial perfusion scintigraphy and three-dimensional echocardiography in ejection fraction and cardiac volumes for determination of the nearest filtering parameters
  3. 1303
    “…BACKGROUND: Development of a core outcome set (COS) for clinical trials for COVID-19 is urgent because of the pandemic wreaking havoc worldwide and the heterogeneity of outcomes in clinical trials. …”
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    Core Outcome Set for Clinical Trials of COVID-19 Based on Traditional Chinese and Western Medicine
  4. 1304
    por Lee, Alice, Davies, Anna, Young, Amber E
    Publicado 2020
    “…OBJECTIVES: A core outcome set (COS) describes a minimum set of outcomes to be reported by all clinical trials of one healthcare condition. …”
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    Systematic review of international Delphi surveys for core outcome set development: representation of international patients
  5. 1305
    “…A solution for this lack of uniformity in reporting of outcomes is the development of a Core Outcome Set (COS) for FI. This paper describes the protocol for the development of a European COS for FI. …”
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    The development of a faecal incontinence core outcome set: an international Delphi study protocol
  6. 1306
    “…Taken together, the CVSMCs and COs exhibited similar molecular changes in the ECM. …”
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    Analysis of crucial genes, pathways and construction of the molecular regulatory networks in vascular smooth muscle cell calcification
  7. 1307
    “…RESULTS: Among 986 ART cycles, COS was given for 9.9±1.8 days (First-day r-hFSH dose of 220.7±68.9 IU; mean total dose of 2184.3±837.5 IU). …”
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    Clinical Efficacy of Follitropin Alfa in GnRH-Antagonist Protocols: A Prospective Observational Phase IV Study on the Use of Biosimilar Follitropin Alfa r-hFSH in Assisted Reproductive Technology in a Routine Care Setting
  8. 1308
    “…This proposed COS in TD will improve the value of data, facilitate high-quality evidence synthesis and evidence-based decision-making. …”
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    Study protocol to develop a core outcome set for thyroid dysfunction to bridge the unmet needs of patient-centred care
  9. 1309
    “…OBJECTIVES: This audit assesses communication between community optometrists (COs) and hospital eye service (HES) in Scotland and England. …”
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    Referrals from community optometrists to the hospital eye service in Scotland and England
  10. 1310
    “…INTRODUCTION: Knowledge about the factors that contribute to the correctional officer’s (CO) mental health and well-being, or best practices for improving the mental health and well-being of COs, have been hampered by the dearth of rigorous longitudinal studies. …”
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    CCWORK protocol: a longitudinal study of Canadian Correctional Workers’ Well-being, Organizations, Roles and Knowledge
  11. 1311
    “…After that, the diameters of EBs and COs were measured regularly under a reverted microscope. …”
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    Resveratrol’s neural protective effects for the injured embryoid body and cerebral organoid
  12. 1312
    “…This paper presents the protocol for the development of a core outcome set (COS) for school-based intervention studies aimed at childhood overweight prevention. …”
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    Development of a core outcome set for school-based intervention studies on preventing childhood overweight and obesity: study protocol
  13. 1313
    “…In order to generate host:tumor organoids, we co-cultured RFP-labeled U87MG cells with fully formed COs. Compound 1 and MON reduced U87MG tumor size in the COs after four days of treatment and induced a significant reduction of PARP expression. …”
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    Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
  14. 1314
    “…OBJECTIVES: To develop a core outcome set (COS) for physical activity interventions in primary schools. …”
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    Developing a core outcome set for physical activity interventions in primary schools: a modified-Delphi study
  15. 1315
    “…CONCLUSIONS: FSH/LH ratios are useful predictors of poor ovarian response or reproductive potential throughout the entire COS with the GnRH antagonist protocol. Our findings also provide insights into the potential for LH supplementation and regimen adjustment during COS to achieve improved outcomes.…”
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    The serum follicle stimulating hormone-to-luteinizing hormone ratios can predict assisted reproductive technology outcomes in women undergoing gonadotropin releasing hormone antagonist protocol
  16. 1316
    “…Consensus on appropriate outcome measures has not been reached, and given the clinical and research interest, a core outcome set (COS) would be beneficial. OBJECTIVES: To collate outcomes currently reported across the cranioplasty literature which will subsequently be used in developing a cranioplasty COS. …”
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    Towards a core outcome set for cranioplasty following traumatic brain injury and stroke 'A systematic review of reported outcomes'
  17. 1317
    “…Our findings provide novel insights into the protective role of COS against acute kidney injury.…”
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    Chitosan oligosaccharide attenuates acute kidney injury and renal interstitial fibrosis induced by ischemia-reperfusion
  18. 1318
    “…In addition, CRPV E6 and E7 oncogenes were transiently expressed in COS-7 cells. Efficiency and safety of LPPs were evaluated in both VX2 cells and the COS-7 cell line. …”
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    RNAi-Mediated Knockdown of Cottontail Rabbit Papillomavirus Oncogenes Using Low-Toxicity Lipopolyplexes as a Paradigm to Treat Papillomavirus-Associated Cancers
  19. 1319
    Publicado 1989
    “…To analyze whether this selective degradation was because of different intrinsic susceptibility of the individual chains to degradation or to the formation of resistant oligomers, TCR chains were expressed alone or in combinations in COS-1 fibroblasts. These studies showed that (a) individual TCR chains were degraded at different rates when expressed alone in COS-1 cells, and (b) sensitive chains could be stabilized by coexpression with a resistant chain. …”
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    Pre-Golgi degradation of newly synthesized T-cell antigen receptor chains: intrinsic sensitivity and the role of subunit assembly
  20. 1320
    Publicado 1993
    “…Taken together, these results define the unique COOH-terminal cytoplasmic sequences of the GLUT1 and GLUT4 glucose transporters as important determinants of cellular localization in COS-7 and CHO cells.…”
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    Exofacial epitope-tagged glucose transporter chimeras reveal COOH- terminal sequences governing cellular localization
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