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2021“…PURPOSE: The purpose of this study was to determine the impact of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), statin, and cyclooxygenase 2 (COX-2) inhibitor on the development of kidney, prostate, and urothelial cancers by analyzing the Korean National Health Insurance Service–National Sample Cohort (NHIS-NSC) database. …”
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2022por Liu, Pan, Li, Huixiang, Luan, Ruiling, Huang, Guiyan, Liu, Yanan, Wang, Mengdi, Chao, Qiuli, Wang, Liying, Li, Danna, Fan, Huaying, Chen, Daquan, Li, Linyu, Matsuzaki, Keiichi, Li, Wei, Koike, Kazuo, Zhao, FengEnlace del recurso
Publicado 2019
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2023por Molino, Antonio, Terlizzi, Michela, Colarusso, Chiara, Rossi, Antonietta, Somma, Pasquale, Saglia, Alessandro, Pinto, Aldo, Sorrentino, RosalindaEnlace del recurso
Publicado 2019
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2024por Zhang, Sipei, Guo, Nan, Wan, Guoyun, Zhang, Tao, Li, Chunyu, Wang, Yongfei, Wang, Yinsong, Liu, Yuanyuan“…Celecoxib (CXB), a selective COX-2 inhibitor, can dramatically enhance the cytotoxicity of doxorubicin (DOX) in breast cancer cells overexpressing P-gp. …”
Publicado 2019
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2025
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2026por Zhu, Texuan, Chen, Jingfei, Zhao, Yanhua, Zhang, Jiejie, Peng, Qiaozhen, Huang, Jingrui, Luo, Jiefeng, Zhang, Weishe“…In addition, a significant positive correlation was observed between the amount of phosphorylated p65 and the levels of COX-2 and IL-6, and between the amount of phosphorylated c-Jun and COX-2 and IL-6 levels. …”
Publicado 2019
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2027por Hwang, Jiyoung, Kim, Donghwa, Park, Jae Sung, Park, Hyen Joo, Shin, Jongheon, Lee, Sang Kook“…Therefore, the inhibition of COX-2 is an important approach to maintain skin health and prevent skin inflammation and carcinogenesis. …”
Publicado 2020
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2028por Miuma, Satoshi, Miyamoto, Junya, Taura, Naota, Fukushima, Masanori, Sasaki, Ryu, Haraguchi, Masafumi, Shibata, Hidetaka, Sato, Shuntaro, Miyaaki, Hisamitsu, Nakao, Kazuhiko“…No significant difference was seen between the IFN-free DAA (-) and IFN-free DAA (+) groups in the landmark time and time-dependent Cox proportional hazards model analyses. However, IFN-free DAA therapy tended to decrease the HCC recurrence rate after curative treatment for primary HCC in patients with chronic hepatitis. …”
Publicado 2020
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2029por Rahman, Md Ridwanur, Faiz, Mohammad Abul, Nu, Ma Yin, Hassan, Md Rafiqul, Chakrabarty, Ashish Kumar, Kabir, Iqbal, Islam, Khaleda, Jafarullah, Abul Kashem Mohammad, Alakabawy, Mariam, Khatami, Ameneh, Rashid, Harunor“…Methods: A questionnaire was developed to conduct face to face interviews among Rohingya refugees in Cox’s Bazar, Bangladesh in November–December 2017. …”
Publicado 2020
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2030por Qiu, Xianxin, Gao, Jing, Yang, Jing, Hu, Jiyi, Hu, Weixu, Kong, Lin, Lu, Jiade J.“…However, it is controversial which method between RSF and traditional cornerstone method Cox proportional hazards (CPH) is better fitted. …”
Publicado 2020
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2031por Zhao, Minghui, Wang, Yiwei, Zhao, Yucui, He, Sijia, Zhao, Ruyi, Song, Yanwei, Cheng, Jin, Gong, Yanping, Xie, Jianzhu, Wang, Yulan, Hu, Binjie, Tian, Ling, Huang, Qian“…Our findings reveal that caspase-3 promotes tumor repopulation in NSCLC cells by activating DDR and the downstream Cox-2/PGE(2) axis. Thus, caspase-3-induced ATM/p53/Cox-2/PGE(2) signaling pathway could provide potential therapeutic targets to reduce NSCLC recurrence after radiotherapy.…”
Publicado 2020
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2032por Lee, Soon-Young, Kim, Min-Hee, Kim, Seung-Hyun, Ahn, Taeho, Kim, Sung-Won, Kwak, Yi-Seong, Cho, Ik-Hyun, Nah, Seung-Yeol, Cho, Seung-Sik, Park, Kyung Mok, Park, Dae-Hun, Bae, Chun-Sik“…RESULTS: KRGWE affected ovalbumin-induced changes, such as increased white blood cell counts, increased IgE levels, and morphological changes (mucous hypersecretion, epithelial cell hyperplasia, inflammatory cell infiltration) by downregulating cytokines such as IL-12, IL-4, and IL-6 via GATA-3 inactivation and suppression of inflammation via NF-κB/COX-2 and PGE(2) pathways. CONCLUSION: KRGWE is a promising drug for asthma treatment.…”
Publicado 2021
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2033por Liu, Xingyu, Su, Jie, Wang, Geng, Zheng, Lihua, Wang, Guannan, Sun, Ying, Bao, Yongli, Wang, Shuyue, Huang, Yanxin“…Meanwhile, the overexpression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) diminished significantly with the presence of HY in response to LPS stimulation. …”
Publicado 2021
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2034por Lin, Yen-Ju, Flaczyk, Adam, Wolfheimer, Sonja, Goretzki, Alexandra, Jamin, Annette, Wangorsch, Andrea, Vieths, Stefan, Scheurer, Stephan, Schülke, Stefan“…In co-cultures of LA-4 cells with mDCs, rFlaA:Betv1-stimulated LA-4 cells p38-MAPK- and COX2-dependently secreted PGE(2), which modulated DC responses by suppressing pro-inflammatory IL-12 and TNF-α secretion. …”
Publicado 2021
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2035
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2036Publicado 2022“…Western blot assay was used to detect the expression of COX6B1 in each group of A549 cells. Double luciferase assay was used to verify the targeted binding relationship between miR-30b-3p and COX6B1. …”
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2037por Ragab, Amany E., Al-Madboly, Lamiaa A., Al-Ashmawy, Ghada M., Saber-Ayad, Maha, Abo-Saif, Mariam A.“…In vivo investigation included evaluation of the rat gastric mucosa for malondialdehyde (MDA), catalase activity, COX2, TNF-α, and key autophagy gene expression. …”
Publicado 2022
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2038por Garrido‐Cano, Iris, Adam‐Artigues, Anna, Lameirinhas, Ana, Blandez, Juan F., Candela‐Noguera, Vicente, Rojo, Federico, Zazo, Sandra, Madoz‐Gúrpide, Juan, Lluch, Ana, Bermejo, Begoña, Sancenón, Felix, Cejalvo, Juan Miguel, Martínez‐Máñez, Ramón, Eroles, PilarEnlace del recurso
Publicado 2022
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2039por Akhter, Shanila, Irfan, Hafiz Muhammad, Alamgeer, Ullah, Aman, Jahan, Shah, Roman, Muhammad, Latif, Muhammad Bilal, Mustafa, Zaid, Almutairi, Farooq M., Althobaiti, Yusuf S.“…These findings demonstrated that all doses of noscapine hydrochloride (10, 20 and 40 mg/kg) studied in this study, significantly (p < 0.001) decreased the protein denaturation by preventing the increase in levels of interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), nuclear factor-kB (NF-kB), cyclooxygenase-2 (COX-2) and prostaglandin E2. Noscapine hydrochloride significantly reduced the paw volume (p < 0.001), arthritic scoring and reversed the body mass as compared to arthritic control diseased rats.…”
Publicado 2022
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2040“…The AUC were 0.795 for RSF and 0.715 for Cox in the training set while the AUC were 0.765 for RSF and 0.705 for Cox in the validation set. …”
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