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  1. 2041
    por Vandivier, Steve
    Publicado 2002
    Libro
    Manual de Oracle9i application server portal /
  2. 2042
    Publicado 2005
    Libro
    Ingredientes /
  3. 2043
    por Goldratt, Eliyahu M., 1948-2011
    Publicado 2007
    Libro
    La meta : un proceso de mejora continua
  4. 2044
    Libro
    A singular marriage : a labour love story in letters and diaries
  5. 2045
    por Lehninger, Albert L.
    Publicado 1993
    Libro
    Principles of biochemistry : with an extended discussion of oxygen-binding proteins
  6. 2046
    por Goldratt, Eliyahu M., 1948-2011
    Publicado 2014
    Libro
    La meta : un proceso de mejora continua /
  7. 2047
    por Cox, Brian, 1968-
    Publicado 2015
    Libro
    El universo cuántico : y por qué todo lo que puede suceder, sucede /
  8. 2048
    “…EPA increased cyclooxygenase-2 (COX-2) expression and protein kinase A (PKA) activity at the differentiation stage, which could explain the inhibitory actions of EPA. …”
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    Eicosapentaenoic Acid Induces the Inhibition of Adipogenesis by Reducing the Effect of PPARγ Activator and Mediating PKA Activation and Increased COX-2 Expression in 3T3-L1 Cells at the Differentiation Stage
  9. 2049
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    Correction: Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKβ/NF-κB signaling pathway in lung cancer cells
  10. 2050
    “…These same plasma samples also inhibited both COX-1 and COX-2 enzyme activity ex vivo but the effect was more pronounced on the enzyme activity of COX-2 enzyme. …”
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    Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE(2 )production in human chondrocytes in vitro
  11. 2051
    “…To evaluate their involvement in the regulation of mPGES-1 and COX-2 expression, we used specific inhibitors as well as phosphorylation analysis. …”
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    Signal pathways JNK and NF-κB, identified by global gene expression profiling, are involved in regulation of TNFα-induced mPGES-1 and COX-2 expression in gingival fibroblasts
  12. 2052
    “…BBR also suppressed the nuclear translocation of p50/p65 NF-κB proteins and their binding to COX-2 promoter, causing inhibition of COX-2. BBR also downregulated HIF-1α and VEGF expression and inhibited Akt and ERK phosphorylation. …”
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    Berberine Targets AP-2/hTERT, NF-κB/COX-2, HIF-1α/VEGF and Cytochrome-c/Caspase Signaling to Suppress Human Cancer Cell Growth
  13. 2053
    “…Additionally the expression of COX-2 mRNA and COX-2–derived PGE(2) were down-regulated by 83b1 in a dose-dependent manner in ESCC cell lines. …”
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    Anti-cancer Effects of a Novel Quinoline Derivative 83b1 on Human Esophageal Squamous Cell Carcinoma through Down-Regulation of COX-2 mRNA and PGE(2)
  14. 2054
    “…The severity of OSAHS was positively correlated with COX-2 levels.…”
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    Liver X Receptor Gene Expression is Enhanced in Children with Obstructive Sleep Apnea-Hyperpnoea Syndrome and Cyclooxygenase-2 (COX-2) is Correlated with Severity of Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS)
  15. 2055
    “…Significant suppressions in the expression level of important members of the iNOS-mediated COX-2 induction pathway and the phosphorylation of mitogen-activated protein kinase members were detected. …”
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    Butanol extracts of Asparagus cochinchinensis fermented with Weissella cibaria inhibit iNOS-mediated COX-2 induction pathway and inflammatory cytokines in LPS-stimulated RAW264.7 macrophage cells
  16. 2056
    “…IHC assay, ELISA, RT-PCR assay, and Western blot assay were used to test relevant cytokines of Cox-2/PGE2-PI3K/AKT/GSK3β/β-catenin pathway. The results showed that CWP can suppress relevant cytokines of Cox-2/PGE2-PI3K/AKT/GSK3β/β-catenin pathway. …”
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    Compound Wumei Powder Inhibits the Invasion and Metastasis of Gastric Cancer via Cox-2/PGE2-PI3K/AKT/GSK3β/β-Catenin Signaling Pathway
  17. 2057
    “…BACKGROUND: Cyclooxygenase-2 (COX-2), the inducible COX form, is a bi-functional membrane-bound enzyme that typically metabolizes arachidonic acid (downstream ω-6 fatty acid) to form 2-series of prostaglandins known to be involved in cancer development. …”
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    Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-γ-linolenic acid peroxidation dependent mechanism
  18. 2058
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    Epoxymicheliolide, a novelguaiane-type sesquiterpene lactone, inhibits NF-κB/COX-2 signaling pathways by targeting leucine 281 and leucine 25 in IKKβ in renal cell carcinoma
  19. 2059
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    Corrigendum to “Naturally occurring sesquiterpene lactones and their semi-synthetic derivatives modulate PGE2 levels by decreasing COX2 activity and expression” [Heliyon 5 (3) (March 2019) e01366]
  20. 2060
    “…Early-stage and whole-stage intervention groups effectively attenuated expression levels of NFκB and COX2 proteins compared with the simple exposed group (all P<0.05). …”
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    Dietary natural astaxanthin at an early stage inhibits N-nitrosomethylbenzylamine–induced esophageal cancer oxidative stress and inflammation via downregulation of NFκB and COX2 in F344 rats
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