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  1. 2141
    “…We initially found that Giardia challenge induced up-regulation of IL-1β, IL-6, TNF-α, prostaglandin (PG) E2, and COX-2 in macrophages, and pretreatment of the cells with COX-2 inhibitor NS398 reduced expressions of those pro-inflammatory factors. …”
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    COX-2 is required to mediate crosstalk of ROS-dependent activation of MAPK/NF-κB signaling with pro-inflammatory response and defense-related NO enhancement during challenge of macrophage-like cell line with Giardia duodenalis
  2. 2142
    por Byham, William C.
    Publicado 1995
    Libro
    Zapp! : la energía inspiradora y vigorizante que aumentará el éxito /
  3. 2143
    Libro
    Miguel Covarrubias caricatures
  4. 2144
    “…HOCbl/NOS/(•)NO regulation is reciprocally associated with lower 4 h expression of TNF-α, IL-1β, COX-2, and lower circulating TNF-α, but not IL-6. …”
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    Biphasic Modulation of NOS Expression, Protein and Nitrite Products by Hydroxocobalamin Underlies Its Protective Effect in Endotoxemic Shock: Downstream Regulation of COX-2, IL-1β, TNF-α, IL-6, and HMGB1 Expression
  5. 2145
    “…BACKGROUND: Arachidonic acid (AA) metabolic enzymes including cyclooxygenase-2 (COX-2), microsomal prostaglandin E synthase-1 (mPGES-1) and cytochrome P450 (CYP) 4A11 play important roles in glioma angiogenesis. …”
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    Inhibition of COX-2, mPGES-1 and CYP4A by isoliquiritigenin blocks the angiogenic Akt signaling in glioma through ceRNA effect of miR-194-5p and lncRNA NEAT1
  6. 2146
    “…Down‐regulation of miR‐34a‐5p inhibited the expression of interleukin‐1β (IL‐1β)/cyclooxygenase 2 (COX2)/prostaglandin E2 (PGE2), decreased IL‐1β, PGE2 and CGRP release, and up‐regulated the expression of silencing information regulator 1 (SIRT1) in trigeminal ganglion, whereas overexpression of miR‐34a‐5p enhanced the expression of IL‐1β/COX2/PGE2, increased the release of IL‐1β, PGE2 and CGRP, and decreased the expression of SIRT1 in trigeminal ganglion. …”
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    miR‐34a‐5p up‐regulates the IL‐1β/COX2/PGE2 inflammation pathway and induces the release of CGRP via inhibition of SIRT1 in rat trigeminal ganglion neurons
  7. 2147
    “…Of these, let-7f-5p showed reproducibly lower level in the blood and lung of the BIPF model rat, and the expression levels of PI3K/AKT/COX2 signaling pathway genes (PIK3CA, PDK1, Akt1, IKBKA, NF-κB1 and COX2) were increased in the lung of BIPF model rats, suggesting that there is a potential correlation between BIPF and the PI3K/AKT/COX2 signaling pathway. …”
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    MicroRNA let-7f-5p regulates PI3K/AKT/COX2 signaling pathway in bacteria-induced pulmonary fibrosis via targeting of PIK3CA in forest musk deer
  8. 2148
    por Nichols, Rose Standish
    Publicado 1902
    Libro
    English pleasure gardens
  9. 2149
    por Cox, Brian, 1968-
    Publicado 2013
    Libro
    ¿Por qué E=mc2? : ¿y por qué debería importarnos?
  10. 2150
    Libro
    Youth, a narrative ; Heart of darkness ; The end of the tether /
  11. 2151
    “…SD also decreases protein levels of COX-2, and increases degradation of phospholipases PLA(2) and PLC(γ)1 and diminishes enzymatic activity of the Ca(2+)-dependent cPLA(2). …”
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    Sarcophine-Diol Inhibits Expression of COX-2, Inhibits Activity of cPLA(2), Enhances Degradation of PLA(2) and PLC(γ)1 and Inhibits Cell Membrane Permeability in Mouse Melanoma B(16)F(10) Cells
  12. 2152
    “…PURPOSE: Tumor necrosis factor-α (TNF-α) has been shown to exert as a pathogenic factor in cardiac fibrosis and heart failure which were associated with the up-regulation of cyclooxygenase (COX)-2/prostaglandin E(2) (PGE(2)) axis. However, whether TNF-α-induced COX-2/PGE(2) upregulation mediated through ROS-dependent cascade remains elusive in human cardiac fibroblasts (HCFs). …”
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    Upregulation of COX-2 and PGE(2) Induced by TNF-α Mediated Through TNFR1/MitoROS/PKCα/P38 MAPK, JNK1/2/FoxO1 Cascade in Human Cardiac Fibroblasts
  13. 2153
    por Cox, Brad J., 1944-
    Publicado 1993
    Libro
    Programación orientada a objetos : un enfoque evolutivo
  14. 2154
    “…RESULTS: Areca nut extract (ANE) stimulated PGE(2)/PGF(2α) production, and upregulated the expression of cyclooxygenase-2 (COX-2), cytochrome P450 1A1 (CYP1A1) and hemeoxygenase-1 (HO-1), but inhibited expression of keratin 5/14, cyclinB1 and cdc25C in GK cells. …”
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    Areca Nut Components Affect COX-2, Cyclin B1/cdc25C and Keratin Expression, PGE2 Production in Keratinocyte Is Related to Reactive Oxygen Species, CYP1A1, Src, EGFR and Ras Signaling
  15. 2155
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    DNA Binding Test, X-Ray Crystal Structure, Spectral Studies, TG-DTA, and Electrochemistry of [CoX(2)(dmdphphen)] (Dmdphphen Is 2,9-Dimethyl-4,7-diphenyl-1,10-phenanthroline, X = Cl, and NCS) Complexes
  16. 2156
    “…CONCLUSIONS: Silencing ACAT1 attenuates Aβ(25–35)-induced cytotoxicity and cell apoptosis in SH-SY5Y cells, which may due to the synergistic effect of ACAT1 and COX2 through PKC/ERK pathways.…”
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    Silencing the ACAT1 Gene in Human SH-SY5Y Neuroblastoma Cells Inhibits the Expression of Cyclo-Oxygenase 2 (COX2) and Reduces β-Amyloid-Induced Toxicity Due to Activation of Protein Kinase C (PKC) and ERK
  17. 2157
    por Lehninger, Albert L.
    Publicado 1993
    Libro
    Principios de bioquímica
  18. 2158
    por Cox, Mike, 1945-
    Publicado 2007
    Libro
    Metadatos descriptivos para televisión : una introducción de extremo a extremo /
  19. 2159
    por Goldratt, Eliyahu M., 1948-2011
    Publicado 2000
    Libro
    La meta : un proceso de mejora continua /
  20. 2160
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    Do COX-2 inhibitors provide additional pain relief and anti-inflammatory effects in patients with rheumatoid arthritis who are on biological disease-modifying anti-rheumatic drugs and/or corticosteroids? Post-hoc analyses from a randomized clinical trial with etoricoxib
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