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2161por Verrall, Geoffrey Mark“…Analyzing commonly available and inexpensive immunomodulatory and anti-inflammatory medications to assess their possible effectiveness in improving the host response to COVID-19, this paper recommends the following: (1) optimize current health—cease (reduce) smoking, ensure adequate hypertension and diabetes control, continue exercising; (2) start on an HMG CoA reductase inhibitor “statin” for its immunomodulatory and anti-inflammatory properties, which may reduce the mortality associated with ARDS; and (3) consider using Diclofenac (or other COX-2 inhibition medications) for its anti-inflammatory and virus toxicity properties. …”
Publicado 2020
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2162“…Besides, TNM stage, operation history, sIL-2R, and CA724 were considered as 4 highly correlated predictors for modeling based on LASSO-Cox regression. Additionally, we respectively used training dataset and validation dataset for establishment including internal validation and external validation, and the prediction performance of model was measured by concordance index (C-index), integrated discrimination improvement, and net reclassification indices (NRI). …”
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2166“…Elevated levels of cyclooxygenase-2 (COX-2) and prostaglandin E(2) (PGE(2)) are indicators of a poor prognosis in breast cancer. …”
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2167por Lee, Hyun Ah, Koh, Eun Kyoung, Sung, Ji Eun, Kim, Ji Eun, Song, Sung Hwa, Kim, Dong Seob, Son, Hong Joo, Lee, Chung Yeoul, Lee, Hee Seob, Bae, Chang Joon, Hwang, Dae Youn“…Taken together, these results suggest that EaEAC suppresses inflammatory responses through inhibition of NO production, COX-2 expression and ROS production, as well as differential regulation of inflammatory cytokines and cell cycle in RAW264.7 cells. …”
Publicado 2017
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2168“…Next-generation sequencing (NGS) identified three baseline ALK fusions: COX7A2L–ALK (C[intragenic]:A20), LINC01210–ALK (L[intergenic]:A20) and ATP13A4–ALK (A9:A19). …”
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2171“…In contrast COX-2, CYR61, and HB-EGF transcription were regulated in a calcium-dependent, COX-2 independent, manner. …”
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2179por Lin, Yan-Jyun, Yang, Chien-Chung, Lee, I-Ta, Wu, Wen-Bin, Lin, Chih-Chung, Hsiao, Li-Der, Yang, Chuen-Mao“…The detailed mechanisms underlying SiNP-induced COX-2 expression and PGE(2) synthesis remain unknown. …”
Publicado 2023
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